10596 results for 'rang after'

Immunology · Complement SystemThe Alternative Complement PathwayThe alternative pathway is one of three routes that activate complement — an antibody-independent, always-on surveillance system d

Introduction to CD73 and Tumor Immunosuppression CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of various cells, including tumor cells and immune cells. It p

The inflammasome is one of the few innate pathways that destroys the cell it activates. A macrophage that assembles NLRP3 has committed to a decision it cannot reverse: a priming signal through TLR4

By Sophie Arthur How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what I

PD-1 & PD-L1 interaction between T-cells and tumour cells. What are PD-1 and PD-L1? PD-1, also known as programmed cell death 1, is a receptor expressed on t

I'll start this post off with a story. When I was half way through my PhD and I had found my passion for science communication, I approached my supervisor for the first time to ask “Can I ha

Techniques · Molecular CloningGuide to Bacterial Transformation: The Science of Genetic ManipulationBacterial transformation is the process by which bacteria take up foreign DNA — usually a plasmid —

The Double-Edged Sword: How Neutrophil Traps Can Both Help and Hinder Cancer's Spread In the intricate battlefield of the human body, the immune system’s foot soldiers, neutrophils, have long been re

Cell Signalling · MetabolismInsulin Signalling & Receptor Tyrosine KinasesInsulin controls metabolism and growth through the insulin receptor — a receptor tyrosine kinase that branches into the

Cell Signalling · Receptor BiologyGPCRs (G Protein-Coupled Receptors): A Complete GuideG protein-coupled receptors are the largest family of cell-surface receptors in the human genome and the ta

By Charlotte O'Donnell PhD Similar to IL-33, IL-36R ligands are involved in maintaining intestinal homeostasis. Analogous to IL-33, d is locali

During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not what y

CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune

Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating

What is a vaccine? A vaccine is a pharmacological product that gives the recieving patient's immune system a chance to learn how to fight infection with decreased risk of illness. Vacci

Lymphocyte Activation Gene-3 (LAG-3) is an immune checkpoint receptor that plays a critical role in regulating T cell function. In recent years, LAG-3 has emerged as a potential target fo

Introduction to BTLA in Immune Regulation B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that plays a critical role in regulating immune responses by suppressing T

Introduction to CD80 and Its Role in Immune Activation CD80 is a critical immune checkpoint molecule that plays an essential role in T cell activation through co-stimulatory pathways. Exp

Delving into the intricate world of Mitotic Catastrophe, this blog unveils its critical role in cell division and cancer therapy, offering insights into its mechanisms and potential treatments.