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    The Strategic Role of Secondary Antibody Incubation Times in Immunodetection Techniques(Post)

    Secondary antibodies are pivotal in the detection of target antigens in various immunodetection assays such as Western blotting, ELISA (Enzyme-Linked Immunosorbent Assay), and immunohistochemistr ...

    COVID-19 (SARS-CoV-2) Assay Tests(Post)

    Rapid Antibody & Antigen tests available from Assay Genie ...

    A Guide To Tau Proteins & Tauopathies(Post)

    Neuroscience · BiomarkersA Guide to Tau Proteins & TauopathiesTau keeps the neuronal cytoskeleton standing up. When its phosphorylation goes wrong, the same protein becomes the aggregate that def ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    Pyroptosis: A Promising Target for Immunotherapy(Post)

    Pyroptosis is an immunogenic form of cell death, meaning that it triggers an immune response. This makes pyroptosis a potentially promising target for immunotherapies that aim to bo ...

    The Role of Zonulin In Intestinal Permeability (Post)

    Gastroenterology · Barrier BiologyZonulin and Intestinal PermeabilityZonulin is the best-characterised endogenous regulator of intestinal tight junctions — the protein that opens the gut barrier on d ...

    The role of IL-18 in health and disease(Post)

    Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

    Mouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous Routes(Post)

    In Vivo Methods · ProtocolsMouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous RoutesRoute choice and injection technique determine how much of a dose actually reach ...

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    PhD Summit - Two Days of Inspiring Talks(Post)

    PhD Summit - A Virtual Conference ELISA Genie is proud to announce the launch of a groundbreaking virtual conference - PhD Sum ...

    Granulocytes Guide(Post)

    Explore the diverse roles and functionalities of granulocytes - neutrophils, eosinophils, basophils, and mast cells - as they form a critical line of defense in the immune system, res ...

    Innate Immunity: Components, Functions & First Line of Defence(Post)

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    CD25 Marker(Post)

    CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...

    What Causes Acute Pancreatitis?(Post)

    Acute pancreatitis (AP) is a condition in which activated enzymes and inflammatory mediators released from the pancreas cause damage to the pancreas and surrounding tissues. AP is fur ...

    Prostate Cancer Markers : What to Look for in Your Test Results(Post)

    In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

    COVID-19 Biomarkers(Post)

    SARS-CoV-2 Background COVID-19 is characterised by a series of biological markers. In some instances, these biomarkers can be used as potent ...

    ST2 and IL33(Post)

    ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromos ...

    Carbon Dioxide sensing in Immune Cells(Post)

    BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE Million years ago carbon dioxide (CO2) levels used to be consid ...

    Prevention and Risk Mitigation: Strategies to Reduce Hantavirus Exposure in a Changing World(Post)

    As hantavirus cases continue to rise globally, the question becomes not just how to detect infections, but how to prevent them in the first place. Recent epidemiological investigations across Califo ...

    Ovarian Cancer: Symptoms, Causes, Diagnosis and Treatment(Post)

    Ovarian cancer is the fourth most common cancer in women. Ovarian cancer is when the normal cells in the ovary change and grow to form a tumour. Because the ovaries are located deep ...

    Microglial Functions Explained: Immunity, Inflammation & Neurodegeneration(Post)

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    The Blood Brain Barrier: An Overview (Post)

    What is the blood-brain barrier? The Blood-brain barrier (BBB) is a system of vessels that acts as a structural and chemical barrier between the brain and the rest of the body's circul ...

    Understanding Radial Glial Cells: Insights into Neurodevelopmental Processes(Post)

    Radial glial cells are essential in shaping the nervous system, serving dual roles in neurogenesis and structural support during the brain's developmental stages. Key Takeaways: Rad ...

    Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic Pathways(Post)

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    Antibiotic Resistance: The Growing Threat to Human Health(Post)

    Antibiotic resistance is a growing problem in the world today. Antibiotics are becoming less and less effective as bacteria evolve to resist them. This poses a serious threat to hum ...

    Esophageal Cancer: Causes, Symptoms, Diagnosis, Treatment, and Prevention(Post)

    Esophageal cancer is a type of cancer that affects the esophagus, which is the tube that carries food and liquids from your mouth to your stomach. Esophageal cancer can cause many d ...

    AACR 2025 - Scientific Progamme, Venue and Exhibits(Post)

    AACR 2025: Meet Assay Genie at the American Association for Cancer Research Assay Genie is delighted to be attending and exhibiting at AACR 2025 in Chicago, Illinois from the 25-30 ...

    Immunophenotyping by Flow Cytometry and Cell Type Markers(Post)

    Immunophenotyping by Flow Cytometry Immunophenotyping is a technique used in the field of immunology and cell biology to identify and classify cells based on the specific proteins ...

    Hybridoma Technology: Revolutionizing Antibody Production(Post)

    Immunology · Antibody ProductionHybridoma Technology: How Monoclonal Antibodies Are MadeHybridoma technology, pioneered by Georges Köhler and César Milstein in 1975, is the method that made monoclona ...

    Biomarkers in sepsis: Their Role in Early Detection and Management (Post)

    Sepsis, a life-threatening condition, is characterized by a dysregulated immun ...

    Transduction vs Transfection: Understanding Gene Delivery Techniques(Post)

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    In Vitro vs In Vivo: Key Differences & When to Use Each(Post)

    In Vitro vs In Vivo: Complete Comparison + Selection Guide | Research MethodsDiscover the distinct roles of 'In Vivo' and 'In Vitro' in biological research, where one offers a natural co ...

    SfN Neuroscience 2024(Post)

    SfN 2024: Meet Assay Genie at the Society for NeuroscienceAssay Genie is delighted to be attending SfN 2024 in Chicago, Illinois on 5th to the 9th of October at the McCormick Convention ...

    Biofilms: The Bacteria Invaders You Can't Ignore(Post)

    If you've ever had a urinary tract infection, you know all about bacteria. These tiny organisms can invade your body and cause all sorts of problems. But what you may not know is th ...

    Comprehensive Guide to Mononuclear Cells(Post)

    Mononuclear cells, as the name suggests, refer to a group of white blood cells characterized by the presence of a single nucleus. Understanding the nature, function, and significanc ...

    COVID-19에서의 항체 반응: SARS-COV-2 진단 테스트에서의 혈청 전환 영향(Post)

    주요 포인트: COVID-19,SARS-COV-2에의한 유행성 코로나 바이러스 질환은 예비 데이터에 따르면, 전형적인 혈청 전환 및 면역 글로불린 클래스 (이소형) 전환 시간 과정을 따르는 것으로 나타났다. 증상 발병 2 주 후 임상 중증도와 ...

    SITC 2024 - Scientific Programme, Venue & Exhibition(Post)

    SITC 2024: Meet Assay Genie at the Society for Immunotherapy of Cancer Annual MeetingAssay Genie is delighted to be attending and exhibiting at SITC 2024 in Houston, Texas on Friday the ...

    Antibody Light Chains, Heavy Chains, Constant Regions & Tumour-Associated Antigens(Post)

    Immunology · Antibody BiologyAntibody Light Chains, Heavy Chains, Constant Regions & Tumour-Associated AntigensAn antibody’s specificity comes from its variable domains and its biological effect ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

    Tau proteins: An Overview (Post)

    The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative dise ...

    A mechanopharmacology approach to overcome chemoresistance in pancreatic cancer(Post)

    Mechanical forces are common in biological systems and dominate numerous perturbations that are relevant to human physiology and disease. Mechanobiology is a new field that evaluates the ef ...

    Platelets : The Unassuming Heroes of Blood Circulation(Post)

    Platelets, the tiny cellular fragments found in our blood, play a crucial role in maintaining our overall health and well-being. From their role in blood clotting to their involveme ...

    The Role of APOE in Neurodegenerative Diseases(Post)

    Understanding the Role of APOE in Neurodegenerative DiseasesRecent findings reveal that a specific gene variant, APOE, significantly increases the risk of Alzheimer's and Parkinson's diseases, highli ...

    Boiling Proteins for Western Blotting: Optimal Conditions and Best Practices(Post)

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    Lactobacilli - Structure, Metabolism, and Testing(Post)

    Delving into the world of Lactobacilli, this piece explores their structural intricacies, metabolic functions, and the pivotal role they play in human health. These bacteria, key components in ...

    Gut Fungi's Impact on Neurodegenerative Diseases(Post)

    Exploring the Role of Gut Fungi in Neurodegenerative Diseases Neurodegenerative diseases, including dementia, represent a significant challenge to global health. Recent research has begun to uncove ...

    Neurofilament Light chain (NEFL) as a biomarker for neuronal damage(Post)

    Delve into the pivotal role of Neurofilament Light chain (NEFL) in neuron structure and its emerging importance as a biomarker for various neurodegenerative diseases, offering insights into di ...

    The Ebola Virus: What You Need to Know(Post)

    The Ebola virus has been in the news a lot lately, but many people still don't know what it is or how it spreads. In this blog post, we will discuss the basics of the Ebola virus: w ...

    Cancer Research Club March 2020(Post)

    ELISA Genie is delighted to announce the date of our next Cancer Research Club which will be taking place on the 31st of March at TTMI, Trinity College Dublin. This event will foc ...

    Key Players in T Cell Regulation: Lag-3, Tim-3, and TIGIT(Post)

    Understanding Lag-3, Tim-3, and TIGIT: Key Players in T Cell RegulationThe immune system's ability to regulate T cell responses is crucial for maintaining homeostasis and combating diseases such as c ...

    COVID-19's Impact on Brain Aging and Cognitive Decline(Post)

    Impact of COVID-19 on Brain Aging and Cognitive DeclineThe COVID-19 pandemic has had profound effects on various aspects of human health, including mental health. A recent study involving nearly 1,00 ...

    Introducing BioSymposia: The Gathering Place for Science(Post)

    Announcement · Powered by Assay GenieIntroducing BioSymposia: The Gathering Place for ScienceWe’re excited to announce the launch of BioSymposia, our new sister platform and a free home for sc ...

    LAG-3: Key Regulator of T Cell Immunity(Post)

    Exploring LAG-3: A Key Regulator in T Cell ImmunityLAG-3 (Lymphocyte Activation Gene-3) is an inhibitory receptor that plays a crucial role in modulating T cell activation and effector functions. Thi ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    Understanding Zonulin and Its Role in Intestinal Health(Post)

    Understanding Zonulin: Key Regulator of Intestinal Barrier Function Zonulin is a crucial physiological modulator of intercellular tight junctions, playing a significant role in regulating intestina ...

    EGFR Pathway and YAP in Non-Small Cell Lung Cancer(Post)

    Understanding the EGFR Pathway and YAP in Non-Small Cell Lung CancerThe epidermal growth factor receptor (EGFR) pathway plays a pivotal role in the development and progression of non-small cell lung ...

    Immune-Checkpoint Inhibition in Cancer Prevention(Post)

    Harnessing Immune-Checkpoint Inhibition for Cancer Prevention Immune-checkpoint inhibition (ICI) has emerged as a pivotal strategy in cancer therapy, particularly in the context of t ...

    How to Choose a Secondary Antibody(Post)

    The selection of a secondary antibody is a critical step in the experimental design of various immunodetection methods, including Western Blot, ELISA, immunohistochemistry (IHC), and immunofluore ...

    Understanding the Bcl-2 Pathway in Cancer Therapy(Post)

    Understanding the Bcl-2 Pathway: Implications for Cancer Therapy The Bcl-2 family of proteins plays a pivotal role in regulating apoptosis, a crucial process for maintaining cellula ...

    PD-1 Blockade in B-Cell Lymphomas: A Comprehensive Overview(Post)

    Understanding PD-1 Blockade in B-Cell Lymphomas Understanding PD-1 Blockade in B-Cell Lymphomas Introduction The programmed cell death prot ...

    Understanding the mTOR Signaling Pathway: A Key Player in Cell Growth and Metabolism(Post)

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    Hemocytometer Cell Counting Procedure(Post)

    Understanding the Functionality of a Hemocytometer Hemocytometers have be ...

    Kit di Estrazione DNA RNA Virus (Post)

    Kit di Estrazione DNA/RNA Virus Il Kit di Estrazione dell'Acido Nucleico Virale II è stato progettato specificamente per la purificazione efficiente del DNA virale e dell'RNA vir ...

    Cytokine Storms: What happens when the immune system overreacts?(Post)

    Discover the critical role of cytokines as signaling molecules in immune responses, their functions, and the impact of their dysregulation, including cytokine storms. Key Takeaways: C ...

    CV writing tips for scientists(Post)

    Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

    Polyclonal Vs Monoclonal antibodies: Key features (Post)

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    Understanding PIIINP Levels in Canine Liver Fibrosis(Post)

    Understanding PIIINP Levels in Canine Liver FibrosisLiver fibrosis is a significant health concern in dogs, often leading to severe complications if not diagnosed and managed appropriately. This arti ...

    Passaging Hybridoma Cells: A Detailed Guide(Post)

    Hybridoma cells are essential tools for producing monoclonal antibodies and are derived by fusing B lymphocytes (antibody-producing cells) with myeloma cells (cancer cells) to achieve bo ...

    What I learnt from meeting 1000+ researchers(Post)

    Over the past few years I have traversed through academia in a few different guises, first as a PhD student for about 5 years, then onto the traditional route of a post-doc, followed by a sale ...

    Leukemia Inhibitory Factor: An Overview (Post)

    Leukemia Inhibitory Factor and JAK-STAT Signalling Pathway Leukemia inhibitory factor (LIF) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. Other members of ...

    PD-L1 in Cancer Immunotherapy: Key Insights(Post)

    PD-L1 in Cancer Immunotherapy: Insights from Recent ResearchRecent advancements in cancer immunotherapy have underscored the critical role of programmed death-ligand 1 (PD-L1) in mediating immune eva ...

    ILC2: The Immune Cell That Fights Allergies and Infections(Post)

    ILC2 - Function, Cytokines, and Role in Health and Disease A quick guide to IL2C ...

    SARS-CoV-2检测试剂盒──用于冠状病毒检测(2019-nCoV株) | Assay Genie(Post)

    SARS-CoV-2检测试剂盒──用于冠状病毒检测(2019-nCoV株)的一步式RT-qPCR试剂盒 用于可靠且可再生的一步式冠状病毒检测(2019-nCo ...

    The Notch Signalling Pathway: Its Steps and Impacts(Post)

    Notch signalling pathway review The Notch signalling pathway is a highly conserved intercellular signalling pathway that regulates various cellular processes. The Notch receptor is a t ...

    Stem Cells: What Are They and How They Can Help Treat Diseases(Post)

    Stem Cells: What are they and how they can help treat diseases Stem cells are a unique population of cells that possess the ability to self-renew and differentiate into specialized c ...

    Networking tips for scientists(Post)

    During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

    Narsoplimab: Targeting MASP-2 to Advance Therapies in Immune-Mediated Disorders(Post)

    Quick Facts About NarsoplimabWhat is Narsoplimab?Narsoplimab is a human monoclonal antibody that targets MASP-2, a key enzyme in the lectin pathway of the complement system.What is the ...

    Anti-Tag Antibodies(Page)

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    Arrays (Page)

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    Custom Antibody(Page)

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    Epigenetic Antibodies(Page)

    Epigenetic Antibodies | 81+ Histone Acetylation & Methylation Antibodies | Assay Genie .page-heading, .page-title, .breadcrumbs, .breadcrumb-list, nav.breadcrumbs { display: none !imp ...

    Antibodies(Page)

    Research Antibodies: Primary, Secondary & In Vivo | Assay Genie .page-content-body{border:none!important;} .page-heading, .page-title, .breadcrumbs, .breadcrumb-list, nav.breadcrumbs ...

    Interactive Pathway Diagrams(Page)

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    Proteins(Page)

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    GeniePlex Multiplex Immunoassay FAQ(Page)

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    Mycoplasma Troubleshooting Tips & FAQ(Page)

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    TCA Cycle Assays(Page)

    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

    Resources - Mandarin(Page)

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    Genieplex Multiplex Citations(Page)

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    Secondary Antibodies(Page)

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    Immunohistochemical Staining, Antibodies & Buffers(Page)

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    Custom Multiplex Assay(Page)

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    Custom In Vivo Antibodies(Page)

    Custom In Vivo Antibody Service | Assay Genie .page-content-body{border:none!important;} .page-heading, .page-title, .breadcrumbs, .breadcrumb-list, nav.breadcrumbs { display: none !impor ...

    GeniePlex Featured Publications(Page)

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    Custom Cell Lines(Page)

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    Custom Protein(Page)

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    Contact Us(Page)

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    Co-Immunoprecipitation (co-IP) Protocol(Page)

    Co-immunoprecipitation Protocol A detailed guide of how Co-IP works, a step by step Co-IP protocol and some hints & tips for your Co-IP workflow! Introductio ...

    Validated Multiplex Panels by Flow Cytometer(Page)

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    GeniePlex Validated Panels by Cytometer(Page)

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