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Tumor-Associated Macrophages: Double Agents in the Cancer Battlefield In the intricate theater of the human body, the immune system acts as a vigilant guardian, dispatching cellular soldiers to seek

Embryonic induced pluripotent stem cells (iPSCs) hold immense potential in the field of regenerative medicine due to their ability to differentiate into various cell types. Understanding the diffe

Impact of COVID-19 on Brain Aging and Cognitive DeclineThe COVID-19 pandemic has had profound effects on various aspects of human health, including mental health. A recent study involving nearly 1,000

COVID-19 Testing Results in 15 Minutes Accurate detection of IgM and IgG patient-generated antibodies with the rapid, point

Cell Signalling · Kinase CascadesMAPK Signaling: The Pathway of Mitogen StimulationThe mitogen-activated protein kinase (MAPK) pathway is one of the most important signalling cascades in biology, conv

Understanding the differentiation pathways of neural stem cells (NSCs) and the identification of lineage-specific markers is a cornerstone in the field of neurobiology and regenerative medicine. T

Enzyme-Linked Immunosorbent Assay (ELISA) is a powerful analytical biochemistry assay that utilizes antibodies and color change to identify a substance. It is widely used in the field of immunolog

Antibiotic resistance is a growing problem in the world today. Antibiotics are becoming less and less effective as bacteria evolve to resist them. This poses a serious threat to human healt

Cancer detection often relies on advanced imaging or invasive procedures, frequently catching the disease at later, more challenging stages. Imagine a future where a simple, non-invasive test could s

By Anusha Senevirante, Post-Doctoral researcher, Imperial College London With non-communicable diseases (or NCDs, which include heart disease, diabetes, ca

Immunology · Myeloid CellsGranulocytes: Neutrophils, Eosinophils and BasophilsGranulocytes are the leukocytes with cytoplasmic granules and lobed nuclei — neutrophils, eosinophils and basophils. They

A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many complex

Chemokines are small signaling proteins that play a crucial role in the immune system by directing the movement of cells, orchestrating immune responses, and maintaining tissue homeostasis. The

Imagine an elite squad of soldiers sent to neutralize a hidden fortress, only to find themselves wandering aimlessly in a thick, disorienting fog just outside the gates. This is the current reality f

The most abundant immunosuppressive molecule in a solid tumour is not a protein. It is adenosine — a metabolite, produced from ATP in two enzymatic steps, at concentrations orders of magnitude above

Nuclear Factor Erythroid 2–Related Factor 2 (NRF2) orchestrates a principal defense mechanism against oxidative stress and plays a pivotal role in inflammation and disease pathogenesis. This artic

The selection of a secondary antibody is a critical step in the experimental design of various immunodetection methods, including Western Blot, ELISA, immunohistochemistry (IHC), and immunofluores