2873 results for 'IFN-β'

Immune Regulation in COVID-19: Immunomodulatory Mechanisms against SARS-CoV-2 Infection What is COVID-19?

Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hema

Ubiquitin is a small, highly conserved protein found in eukaryotic cells that plays a crucial role in regulating various cellular processes. The process of ubiquitination involves the covalent att

SARS-CoV-2 Background COVID-19 is characterised by a series of biological markers. In some instances, these biomarkers can be used as potenti

Blocking TNF cures rheumatoid arthritis in some patients and triggers demyelination in others. That is not a dosing problem, and it is not a patient-selection problem. It is the direct consequence of

Immunology Guide MHC Class I vs Class II: Key Differences & Functions [Guide] Major Histocompatibility Complex molecules present antigens to T

A T-cell engager does not give the T cell an instruction. It gives it an address. A bispecific antibody with one arm on CD3 and the other on a tumour antigen forces two membranes into contact and let

What are Stem Cells? Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organisms

Inflammasomes are complex intracellular structures that play a pivotal role in the immune response by detecting pathogenic microorganisms and sterile stressors. Their activation is a critical step

An antibody–drug conjugate is not a targeted drug. It is a delivery problem with an antibody bolted to the front of it. Binding is the easy part, and it is almost never the part that fails. What deci

The 2025 Nobel Prize in Physiology or Medicine has been awarded to a trio of scientists for their groundbreaking work on peripheral immune tolerance, a mechanism that prevents our immune system from a

A chemokine gradient does not move a leukocyte anywhere. It only tells one that has already stopped which way to go. That sentence is the whole map. Trafficking is a four-step cascade and the steps a

Innate Lymphoid Cells (ILCs) represent a fascinating component of the immune system, playing a crucial role in maintaining tissue homeostasis and mounting rapid responses against pathogens. The

Understanding the differentiation pathways of neural stem cells (NSCs) and the identification of lineage-specific markers is a cornerstone in the field of neurobiology and regenerative medicine. T

By Charlotte O’Donnell PhD Inflammation and Cancer The link between inflammation and cancer is well established, with infl

By Charlotte O'Donnell PhD A role for IL-33 in Barrier Function and Epithelial Wound Healing

A chimeric antigen receptor is a synthetic protein wired into a real signalling pathway. The extracellular half is an antibody fragment; everything below the membrane is borrowed from the T-cell rece