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Co-Inhibitory Checkpoints Beyond PD-1: CTLA-4, LAG-3 and TIM-3

PD-1 gets the attention, but it is one brake among many — and the others do not work the same way. The co-inhibitory receptors are routinely drawn as interchangeable stop signs on a T cell. They are

Co-Inhibitory Checkpoints & T-Cell Exhaustion

Wnt Signalling Pathway in Immunity

What is Wnt Signalling? The Wnt signalling pathway is an evolutionarily conserved pathway that plays critical roles in the regulation of determining cell fate, polari

Metabolic Exhaustion: How Mitochondrial Dysfunction Sabotages CAR-T Cell Therapy in Solid Tumors

Imagine engineering a patient's own immune cells into precision-guided missiles against cancer—cells that can seek out and destroy tumors with remarkable specificity. This is the promise of CAR-T cell

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TCF1/TCF7 Monoclonal Antibody (CAB20835)

MSRP:

Now: $173 - $603

Was:

Product Code:

CAB20835

Antibody Type:

Monoclonal Antibody

MSRP:

Now: $173 - $603

Was:

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TCF7 Rabbit Polyclonal Antibody (CAB3091)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB3091

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TCF7 Transcription Factor Activity Assay (TFAB00132)

MSRP:

$1,360

Was:

Product Code:

TFAB00132

ELISA Type:

Transcription Factor Assay

MSRP:

$1,360

Was:

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HNF1A Rabbit Polyclonal Antibody (CAB3092)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB3092

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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Human TCF7L2/TCF4 ELISA Kit (HUFI01972)

MSRP:

$857

Was:

Product Code:

HUFI01972

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

46.875 pg/mL

Range:

78.125-5000 pg/mL

MSRP:

$857

Was:

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Human Transcription factor 7-like 2 (TCF7L2) ELISA Kit (HUEB2467)

MSRP:

$923

Was:

Product Code:

HUEB2467

Range:

78-5000 pg/mL

ELISA Type:

Sandwich

MSRP:

$923

Was:

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Mouse Transcription factor 7-like 2 (Tcf7l2) ELISA Kit (MOEB2212)

MSRP:

$923

Was:

Product Code:

MOEB2212

Range:

62.5-4000 pg/mL

ELISA Type:

Sandwich

MSRP:

$923

Was:

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LEF1 Rabbit Polyclonal Antibody (CAB0909)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB0909

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TCF12 Rabbit Polyclonal Antibody (CAB4146)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB4146

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TCF15 Antibody (PACO54114)

MSRP:

$384

Was:

Product Code:

PACO54114

Isotype:

IgG

MSRP:

$384

Was:

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Rat Hepatocyte nuclear factor 1-alpha (Hnf1a) ELISA Kit (RTEB1048)

MSRP:

$923

Was:

Product Code:

RTEB1048

Range:

0.156-10 ng/mL

ELISA Type:

Sandwich

MSRP:

$923

Was:

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T-Cell Exhaustion & Checkpoints Antibody Sampler Pack

MSRP:

$1,059

Was:

Product Code:

ABSP024

MSRP:

$1,059

Was:

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TCF4/TCF7L2 Polyclonal Antibody (CAB20770)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB20770

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TCF7L1 Polyclonal Antibody (CAB9006)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB9006

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TCF4/TCF7L2 Rabbit Monoclonal Antibody (CAB19548)

MSRP:

Now: $173 - $603

Was:

Product Code:

CAB19548

Antibody Type:

Monoclonal Antibody

MSRP:

Now: $173 - $603

Was:

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Human TCF7L2 (Transcription Factor 7 Like Protein 2) ELISA Kit (AEKE10676)

MSRP:

$857

Was:

Product Code:

AEKE10676

Detection Method:

Sandwich

Sensitivity:

0.052 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$857

Was:

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TEAD1 Rabbit Polyclonal Antibody (CAB6768)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB6768

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TEAD1 Rabbit Polyclonal Antibody (CAB13366)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB13366

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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TEAD4 Rabbit Polyclonal Antibody (CAB4151)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB4151

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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IKKalpha Rabbit Polyclonal Antibody (CAB2062)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB2062

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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HNF4A Rabbit Polyclonal Antibody (CAB2085)

MSRP:

Now: $127 - $488

Was:

Product Code:

CAB2085

Antibody Type:

Polyclonal Antibody

MSRP:

Now: $127 - $488

Was:

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Mouse HNF4a/Hepatocyte Nuclear Factor 4 Alpha ELISA Kit (MOFI00897)

MSRP:

$857

Was:

Product Code:

MOFI00897

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

23.438 pg/mL

Range:

39.063-2500 pg/mL

MSRP:

$857

Was:

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Human NFE2L1/Nuclear factor erythroid 2-related factor 1 ELISA Kit (HUFI01429)

MSRP:

$857

Was:

Product Code:

HUFI01429

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

46.875 pg/mL

Range:

78.125-5000 pg/mL

MSRP:

$857

Was:

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Anti-LEF1 [R01-9T-1] Monoclonal Antibody (AGMB06461)

MSRP:

$792

Was:

Product Code:

AGMB06461

Antibody Type:

Monoclonal Antibody

MSRP:

$792

Was:

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Anti-LEF1 [R02-3A4] Monoclonal Antibody (AGMB00118)

MSRP:

Now: $165 - $634

Was:

Product Code:

AGMB00118

Antibody Type:

Monoclonal Antibody

MSRP:

Now: $165 - $634

Was:

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Rat RuvB-like 1 (Ruvbl1) ELISA Kit (RTEB1517)

MSRP:

$923

Was:

Product Code:

RTEB1517

ELISA Type:

Sandwich

MSRP:

$923

Was:

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Human RuvB-like 1 (RUVBL1) ELISA Kit (HUEB2405)

MSRP:

$923

Was:

Product Code:

HUEB2405

Range:

0.312-20 ng/mL

ELISA Type:

Sandwich

MSRP:

$923

Was:

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Human HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA Kit (AEKE08908)

MSRP:

$857

Was:

Product Code:

AEKE08908

Detection Method:

Sandwich

Sensitivity:

0.064 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$857

Was:

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Human HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA (Small Sample Volume) (AEKE08909)

MSRP:

$857

Was:

Product Code:

AEKE08909

Detection Method:

Sandwich

Sensitivity:

0.066 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$857

Was:

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Rat HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA (Small Sample Volume) (AEKE03887)

MSRP:

$857

Was:

Product Code:

AEKE03887

Detection Method:

Sandwich

Sensitivity:

0.052 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$857

Was:

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Mouse HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA (Small Sample Volume) (AEKE10415)

MSRP:

$857

Was:

Product Code:

AEKE10415

Detection Method:

Sandwich

Sensitivity:

0.057 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$857

Was:

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TLE4 Colorimetric Cell-Based ELISA (CBCAB01064)

MSRP:

$1,267

Was:

Product Code:

CBCAB01064

ELISA Type:

Cell Based

Detection Method:

Colorimetric

MSRP:

$1,267

Was:

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Rat HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA Kit (AEKE03886)

MSRP:

$989

Was:

Product Code:

AEKE03886

Detection Method:

Sandwich

Sensitivity:

0.053 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$989

Was:

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Mouse HNF1a (Hepatocyte Nuclear Factor 1 Alpha) ELISA Kit (AEKE10414)

MSRP:

$989

Was:

Product Code:

AEKE10414

Detection Method:

Sandwich

Sensitivity:

0.056 ng/mL

Range:

0.16-10 ng/mL

MSRP:

$989

Was:

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Mouse RuvB-like 1 (Ruvbl1) ELISA Kit (MOEB2155)

MSRP:

$923

Was:

Product Code:

MOEB2155

ELISA Type:

Sandwich

MSRP:

$923

Was:

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Human Immunology ELISA Kits 24 Catalase ELISA Kit — Add to Cart

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Human CAT (Catalase) ELISA Kit (HUFI07676) — Add to Cart

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Human CAT (Catalase) ELISA Kit (HUFI07676)

$857

Product Code:

HUFI07676

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

9.375 pg/mL

Range:

15.625-1000 pg/mL

Human IL-6 ELISA Kit (HUFI00180) — Add to Cart

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Human IL-6 ELISA Kit (HUFI00180)

$791

Product Code:

HUFI00180

Sensitivity:

2.813pg/ml

Range:

4.688-300pg/ml

ELISA Type:

Sandwich

Human CRP ELISA Kit (HUFI00088) — Add to Cart

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Human CRP ELISA Kit (HUFI00088)

$857

Product Code:

HUFI00088

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

18.75 pg/mL

Range:

31.25-2000 pg/mL

Hormone and Small Molecule ELISA Kits Serotonin ELISA Kit — Add to Cart

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Serotonin ELISA Kit (UNFI0018)

$857

Product Code:

UNFI0018

Detection Method:

Competitive ELISA, Coated with Antigen

Sensitivity:

0.938 ng/mL

Range:

1.563-100 ng/mL

Human MICA ELISA Kit (HUFI00015) — Add to Cart

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Human MICA ELISA Kit (HUFI00015) — Add to Cart

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Human MICA ELISA Kit (HUFI00015)

$857

Product Code:

HUFI00015

Detection Method:

Sandwich ELISA, Double Antibody

Sensitivity:

46.875 pg/mL

Range:

78.125-5000 pg/mL

Fatty Acid Oxidation (FAO) Assay Kit (BR00001) — Choose Options

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Fatty Acid Oxidation (FAO) Assay Kit (BR00001)

$1,253

Product Code:

BR00001

Instrument:

Microplate Reader

Anti-Mouse IFNAR-1 In Vivo Antibody - Low Endotoxin — Choose Options

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Anti-Mouse IFNAR-1 In Vivo Antibody - Low Endotoxin (IVMB0202)

$210 - $5,001

Product Code:

IVMB0202

Antibody Type:

Functional-Grade In Vivo Antibody

Clone:

MAR1-5A3

Protein:

IFNAR1

Isotype:

Mouse IgG1

Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin — Choose Options

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Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin (IVMB0148)

$210 - $5,001

Product Code:

IVMB0148

Antibody Type:

Functional-Grade In Vivo Antibody

Clone:

PC61

Protein:

CD25

Isotype:

Rat IgG1 lambda

Anti-Mouse NK1.1 In Vivo Antibody - Low Endotoxin — Choose Options

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Anti-Mouse NK1.1 In Vivo Antibody - Low Endotoxin (IVMB0100)

$210 - $5,001

Product Code:

IVMB0100

Antibody Type:

Functional-Grade In Vivo Antibody

Clone:

PK136

Protein:

NK1.1

Isotype:

Mouse IgG2a kappa

Anti-Mouse PD-1 (CD279) [RMP1-14] In Vivo Antibody - Low Endotoxin — Choose Options

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Anti-Mouse PD-1 Antibody [RMP1-14] In Vivo-Low Endotoxin (IVMB0037)

$210 - $5,001

Product Code:

IVMB0037

Antibody Type:

Functional-Grade In Vivo Antibody

Clone:

RMP1-14

Protein:

PD-1

Isotype:

Rat IgG2a kappa

Human GABA Recombinant Protein (RPES4487) — Choose Options

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Human GABA Recombinant Protein (RPES4487)

$139 - $305

Product Code:

RPES4487

Human PSMA Recombinant Protein (RPES2491) — Choose Options

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Human PSMA Recombinant Protein (RPES2491)

$376 - $851

Product Code:

RPES2491

Human CXCL10 Recombinant Protein (RPES1256) — Choose Options

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Human CXCL10 Recombinant Protein (RPES1256)

$210 - $471

Product Code:

RPES1256

Human HBEGF Recombinant Protein (RPES0548) — Choose Options

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Human HBEGF Recombinant Protein (RPES0548)

$139 - $305

Product Code:

RPES0548

Cell Biology Antibodies 4 Anti-LSAMP Antibody CAB14248 — Choose Options

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LSAMP Rabbit Polyclonal Antibody (CAB14248)

$127 - $488

Product Code:

CAB14248

Antibody Type:

Polyclonal Antibody

Cell Cycle Antibodies 1 Anti-MCM4 Antibody CAB13513 — Choose Options

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MCM4 Rabbit Polyclonal Antibody (CAB13513)

$127 - $488

Product Code:

CAB13513

Antibody Type:

Polyclonal Antibody

Cardiovascular Antibodies Anti-VEGF Antibody CAB12303 — Choose Options

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Cardiovascular Antibodies Anti-VEGF Antibody CAB12303 — Choose Options

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VEGF Rabbit Polyclonal Antibody (CAB12303)

$127 - $488

Product Code:

CAB12303

Antibody Type:

Polyclonal Antibody

Hormone and Small Molecule ELISA Kits MDA ELISA Kit — Add to Cart

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MDA ELISA Kit (UNFI0048)

$857

Product Code:

UNFI0048

Detection Method:

Competitive ELISA, Coated with Antigen

Sensitivity:

4.688 ng/mL

Range:

7.813-500 ng/mL

Hormone and Small Molecule ELISA Kits PGE2 ELISA Kit — Add to Cart

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PGE2 ELISA Kit (UNFI0032)

$857

Product Code:

UNFI0032

Detection Method:

Competitive ELISA, Coated with Antigen

Sensitivity:

18.75 pg/mL

Range:

31.25-2000 pg/mL

Hormone and Small Molecule ELISA Kits Dopamine ELISA Kit — Add to Cart

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Dopamine ELISA Kit (UNFI0013) — Add to Cart

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Dopamine ELISA Kit (UNFI0013)

$857

Product Code:

UNFI0013

Detection Method:

Competitive ELISA, Coated with Antigen

Sensitivity:

0.938 ng/mL

Range:

1.563-100 ng/mL