|Product Name:||SOX12 Transcription Factor Activity Assay|
|Sample Types:||Nuclear or cell lysates|
The Assay Genie SOX12 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates
Assay Genie ELISA kits are designed to significantly reduce experiment time and ensure sensitivity and flexibility for high-throughput screening.
|Assay Time:||4.5 hours|
|Detection Method:||Colorimetric 450 nm|
|Size:||12 x 8-Well Microstrips|
|Storage:||4°C for 6 months|
|UniProt Protein Function:||Function: Binds to the sequence 5'-AACAAT-3'|
|UniProt Protein Details:|
Subcellular location: Nucleus Ref.1.
Tissue specificity: Expressed most abundantly in the CNS. Also expressed in fetal brain and kidney and adult heart, pancreas, testis and ovary. Other tissues were only weakly positive. Ref.1
Sequence similarities: Contains 1 HMG box DNA-binding domain.
Sequence caution: The sequence AAB69627.1 differs from that shown. Reason: Frameshift at positions 135 and 201.
|NCBI Summary:||Members of the SOX family of transcription factors are characterized by the presence of a DNA-binding high mobility group (HMG) domain, homologous to the HMG box of sex-determining region Y (SRY). Forming a subgroup of the HMG domain superfamily, SOX proteins have been implicated in cell fate decisions in a diverse range of developmental processes. SOX transcription factors have diverse tissue-specific expression patterns during early development and have been proposed to act as target-specific transcription factors and/or as chromatin structure regulatory elements. The protein encoded by this gene was identified as a SOX family member based on conserved domains, and its expression in various tissues suggests a role in both differentiation and maintenance of several cell types. [provided by RefSeq, Jan 2013]|
|NCBI GenInfo Identifier:||21264339|
|NCBI Gene ID:||6666|
|UniProt Related Accession:||O15370|
|NCBI Full Name:||transcription factor SOX-12|
|NCBI Synonym Full Names:||SRY-box 12|
|NCBI Official Symbol:||SOX12|
|NCBI Official Synonym Symbols:||SOX22|
|NCBI Protein Information:||transcription factor SOX-12|
|UniProt Protein Name:||Transcription factor SOX-12|
|UniProt Synonym Protein Names:||Protein SOX-22|
|Protein Family:||Transcription factor|
|UniProt Gene Name:||SOX12|
|UniProt Entry Name:||SOX12_HUMAN|
|SOX12 Antibody (PACO05107)|