HBP1 Transcription Factor Activity Assay



ELISA Kit Technical Manual

HBP1 Transcription Factor activity assay

Product Description:The Assay Genie HBP1 transcription factor activity assay allows for the detection and qualitative analysis of endogenous levels of activated transcription factors in a variety of nuclear and cell lysates Assay Genie ELISA kits are designed to significantly reduce experiment Time: and ensure sensitivity and flexibility for high-throughput screening.
Target Synonyms:
Detection Target:Phospho-IRAK1(Thr209)
Reactivity:Human, Mouse, Rat
Pack Size:12 x 8-Well Microstrips
Detection Method:Colorimetric 450 nm
Format:transcription factor activity assay
Storage and Stability Guarantee:4 °C/6 Months
Sample Type:Nuclear or cell lysates
Range:See Technical Manual
Time:4.5 hours

HBP1 Transcription Factor activity assay Protein Information

UniProt Protein Function:HBP1: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: 7q22.3

Cellular Component: nucleoplasm

Molecular Function:protein binding; DNA binding; RNA binding

Biological Process: Wnt receptor signaling pathway; regulation of transcription, DNA-dependent; transcription, DNA-dependent; positive regulation of potassium ion transport; cell cycle arrest

UniProt Code:O60381
NCBI GenInfo Identifier:346716352
NCBI Gene ID:26959
NCBI Accession:NP_001231191.1
UniProt Secondary Accession:O60381,Q8TBM1, Q8TE93, Q96AJ2, B3KVB7,
UniProt Related Accession:O60381
Molecular Weight:57,645 Da
NCBI Full Name:HMG box-containing protein 1 isoform 1
NCBI Synonym Full Names:HMG-box transcription factor 1
NCBI Official Symbol:HBP1
NCBI Protein Information:HMG box-containing protein 1; HMG box transcription factor 1; high mobility group box transcription factor 1
UniProt Protein Name:HMG box-containing protein 1
UniProt Synonym Protein Names:HMG box transcription factor 1; High mobility group box transcription factor 1
Protein Family:HMG box-containing protein
UniProt Gene Name:HBP1
UniProt Entry Name:HBP1_HUMAN
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Additional Information

Product Type:
Transcription Factor Assay
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