9514 results for 'Lipase I'

What are MHC Class I molecules? The MHC class I is a glycoprotein that is expressed on all nucleated cells of the human body. MHC class I are important in disease defense against viruses, b ...

RIG-I: Antiviral Properties in COVID-19 (SARS-CoV-2) Infection Key Points RIG-I is a cytosolic RNA ...

Over the past few years I have traversed through academia in a few different guises, first as a PhD student for about 5 years, then onto the traditional route of a post-doc, followed by a sale ...

Major Histocompatibility Complex (MHC) molecules are essential for immune recognition and response. They are specialized glycoproteins that present antigens to T cells, allowing the immu ...

Acute pancreatitis (AP) is a condition in which activated enzymes and inflammatory mediators released from the pancreas cause damage to the pancreas and surrounding tissues. AP is fur ...

What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of ant ...

What is Necrosis? Necrosis is a pathological process characterized by the death of cells or tissues within a living organism. It occurs as a result of various factors, including injury, inf ...

I'll start this post off with a story. When I was half way through my PhD and I had found my passion for science communication, I approached my supervisor for the first time to ask “Can I h ...

Writer’s block can be a big stumbling block when trying to write your PhD thesis, grant or a paper you are trying to get publish. During the early stages of writing my PhD thesis I s ...

Before I even started my PhD I was already thinking about carrying out PostDoc in a foreign country and had my sights set on going to the US. I had previously carried out a degree in Genetic ...

Explore antigen presentation's crucial role in adaptive immunity and its impact on cancer immunotherapy, highlighting the diversity and function of MHC class I molecules. Key Takeawa ...

During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...

Stress and anxiety are a normal part of our daily lives and impact everything we do from our relationships with loved ones to our performance in the laboratory. Like any scientist, I experienced ...

Explore 29 essential tips for crafting a compelling and well-structured PhD thesis, blending effective writing practices with time management and academic rigor for a successful dissertation jour ...

By Dr. Niclas Thomas “Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As f ...

Quick Facts About AnifrolumabWhat is Anifrolumab?Anifrolumab is a monoclonal antibody that targets the type I interferon receptor, playing a crucial role in treating systemic lupus eryt ...

Science communication (Scicomm) is currently on the up. As rebellion against the increasing distrust of science stemmed from bigoted and ignorant leaders, scientists are turning to ...

How to increase lab productivityWhen you look back at some weeks in the lab it seems like you have achieved nothing and your lab productivity can be low. Your cloning hasn’t worked or your mice ...

What is COVID-19 COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spr ...

By Catríona Dowling, Post-Doc, RCSI I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure ...

Alex Lloyd PhD Candidate, Dublin Institute of Technology Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular disease ...

Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

TEST RAPIDO POC COVID-19 Descrizione Il kit Assay Genie solo utilizzo per la ricerca. Il kit rapido C ...

Introduction to KIR Blockade in Cancer ImmunotherapyNatural killer (NK) cells are crucial components of the innate immune system, responsible for recognizing and destroying virally infe ...

Bone Morphogenetic Proteins (BMP) were first discovered in the 1960s by Dr.Marshall Urist, an orthopaedic surgeon at UCLA (Urist 1965). BMPs are classically associated with their roles in limb ...

The STING (Stimulator of Interferon Genes) pathway plays a pivotal role in the innate immune system's response to cancerous cells and DNA viruses. Exploiting this pathway through STING activators ...

I have been in the situation that I’m sure many of us have. I work on genes, which if you name to any right-minded individual, sound like a random string of nonsensical gibberish. So, mayb ...

Writing a Thesis Statement Writing a thesis statement can be a frustrating task, whether you're working on your undergraduate, master's, or PhD degree. Unfortunatel ...

Quick Facts About LitifilimabWhat is Litifilimab?Litifilimab is a monoclonal antibody developed by Biogen targeting BDCA2, a receptor on plasmacytoid dendritic cells (pDCs), to regulate ...

PhD Interview Presentation Dos and Don’ts It is becoming increasingly common for master's and undergraduate students to present data they produced during their rese ...

Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dun ...

The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...

Shelly Pathak PhD candidate, University of Leeds SAIDs Systemic Auto-inflammatory diseases (SAIDs) have been defined as a group of mainly inherited disorde ...

Explore the intricate world of Insulin Signaling and Receptor Tyrosine Kinases (RTKs), pivotal in regulating metabolism and influencing diseases like cancer and atherosclerosis. Key Take ...

The Spanish flu pandemic of 1918-1919 was the deadliest in history. It is estimated that up to 100 million people died from the virus, which is more than three times the number who ...

Interferons are key cytokines in the immune system, crucial for combating viral and bacterial infections, with significant roles in both innate and adaptive immunity responses. Key Takeaways ...

CD8+ T cells, also known as cytotoxic T lymphocytes (CTLs), are a critical component of the immune system. They play a vital role in defending the body against viral infections, intracel ...

Traumatic injuries & death When I ask people what the leading cause of death is in the United States in people age 44 and under, they generally reply saying ...

It’s not uncommon now for Masters or Undergraduate students to present some data or data that they produced during their research for a PhD interview process. Sometimes this can be in front of ...

The lab can be one of the greatest places in the world to make live long friends. Spending countless hours in a tissue culture room late into the middle of the night, sharing similar frustrati ...

What are Natural Killer Cells? Natural Killer (NK) cells are a vital subset of lymphocytes, belonging to the same family as B cells and T cells, collectively known a ...

Throughout my graduate and postgraduate studies I have been really intrigued and fascinated by the mitochondria, the organelle that keeps all of us running everyday! The more I learn about ...

Like needles in a haystack, interesting speakers that bring charisma and rock n roll to their talks are hard to come by. No matter what the research interests of the audience, these speakers h ...

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By Zoe Angel, PhD Student, Ulster University Prostate cancer is now the commonest cancer in men and it is the fifth leading cause of death (1). Researc ...

In the complex world of biochemical processes, enzymes play a crucial role in catalyzing various reactions necessary for life. Among these enzymes, proteases and peptidases are fundamental pla ...

Making the switch! This article provides some help on CV writing tips for scientists for PhDs and PostDocs looking for jobs outside of academia and what they might need to ...

Kit di Estrazione DNA/RNA Virus Il Kit di Estrazione dell'Acido Nucleico Virale II è stato progettato specificamente per la purificazione efficiente del DNA virale e dell'RNA vir ...

The flu is a highly contagious virus that affects the respiratory system. It can cause fever, muscle aches, and coughing. In some cases, it can lead to more serious health complicat ...

Since I am from Ireland I thought I would give as comprehensive view as possible for Research Universities in Ireland. By now you are probably considering looking for a PhD or PostDoc posit ...

Natural killer (NK) cells are a crucial component of the innate immune system and play a significant role in eliminating tumor cells. Unlike T cells, NK cells can recognize and kill canc ...

David Melamed, Phd Candidate, Colombia University When I started in the Kalderon Lab five years ago, I had no idea that our work would lead us to drastica ...

Parkinson's disease (PD) is a progressive neurological disorder that predominantly affects the motor system, leading to a wide range of symptoms including tremors, rigidity, bradykinesia (slowne ...

Platinum based cancer drugs Despite nearly 50% of all anti-cancer treatments being platinum-based, there is an urgent need to develop novel therapeutics ...

By Sophie Arthur How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what ...

Dr. Melissa Conroy, TTMI I am an immunologist and senior research fellow in the Cancer Immunology and Immunotherapy Group, Department of Surgery at Trinit ...

Preeclampsia is a serious condition that can develop during pregnancy. It is marked by high blood pressure and the presence of protein in the urine and can cause serious problems for ...

What is Immunometabolism? Immunometabolism is an exponentially growing, multi-disciplinary field of research aiming at deciphering the dynamic cellular and mol ...

Ralitsa R. Madsen – University of Cambridge Metabolic Research Laboratories Each one of us is the result of an extraordinary developmental proce ...

Stephen Reynolds, PhD Student, CERVIVA and Trinity College Dublin We hear almost daily now how everyone in their lifetime will be touched by cancer either directly or through a close f ...

The Interleukin-1 (IL-1) family represents a crucial group of signaling molecules that play a pivotal role in regulating the immune system and inflammatory responses. Comprising 11 members, in ...

Bone Resorption Explained: Process, Markers, and Clinical InsightsUnravel the complexities of bone resorption, a crucial biological process essential for skeletal health and calcium reg ...

Immunotherapy has become a central pillar in the fight against cancer, with a focus on enhancing the body’s natural defenses. Among the molecules at the forefront of immunotherapeutic re ...

By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

Flow cytometry is a powerful analytical technology employed in cell biology, immunology, and oncology research. It enables the rapid measurement of physical and chemical characteristics of cells ...

As a vital component of the immune system, the Alternative Complement Pathway plays a crucial role in defending the body against pathogens and maintaining immune homeostasis. In this blog, we ...

In the intricate landscape of the immune system, toll-like receptors (TLRs) play a fundamental role in the first line of defense against pathogens. These receptors, essential components of the in ...

Growth factors play a vital role in the complex web of biological processes, serving as key regulators in various essential events. They exert significant influence over cruc ...

Mechanical forces are common in biological systems and dominate numerous perturbations that are relevant to human physiology and disease. Mechanobiology is a new field that evaluates the ef ...

Imagine a microscopic sniper, capable of delivering a lethal blow to a single cancer cell while leaving its healthy neighbors virtually untouched. This is the promise of targeted alpha therapy, a re ...

Mesenchymal stem cells (MSCs) have emerged as pivotal players in the realm of regenerative medicine due to their unique properties and versatile potential. Originally discovered in the bone marro ...

For decades, the fight against cancer has been a story of incremental gains. But what if we could fundamentally shift the battlefield, turning the body's own immune system into a precision-guided wea ...

When PhDs and Post-Docs start in new lab they have the best intentions to keep their lab books up to date with notes, new research methods, data, and protocol information. These best efforts u ...

Mononuclear phagocytes, essential in immunity and homeostasis, perform diverse roles from phagocytosis to tissue repair, influencing health and disease. Key Takeaways: Mononuclear ...

Esophageal cancer is a type of cancer that affects the esophagus, which is the tube that carries food and liquids from your mouth to your stomach. Esophageal cancer can cause many d ...

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Localised ResourcesMultiple languages avaialableAccess research materials in multiple languages, including French, Spanish, Japanese, and more, to support your global research needs.Get ...

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    Chemokines   Key Research Areas       C Chemokine Ligands XCL1/Lymphot ...

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Disease & Pathway ToolsEmpower you Biomedical ResearchDiscover high-quality tools for studying disease pathways, biomarker discovery, and therapeutic development. Ideal for immunolo ...

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ProtocolsComprehensive protocols & guidesWhether you're working in drug development, diagnostics, or translational research, our curated library supports reliable assay performance ...

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1-Step TUNEL Kits Unique 1-Step Non-Toxic Dewaxing Step for Late Stage Apoptosis Detection Explore TUNEL Assays ...

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Phosphorylation ELISA Screen cell lysates without Western Blot analysis! Determine phosphorylated protein to verify pathway activation! ...

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Create your own custom multiplex assay with over 400 analytes to choose from! At Assay Genie we can develop custom assays to meet your research needs within 10 days! To find out more infor ...

Biosimilar AntibodiesValidated for Therapeutic ResearchFunctional-grade biosimilars for in vitro and in vivo experiments, validated to support innovation in drug discovery, molecular bi ...