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Preeclampsia & immune cell regulation | Assay Genie(Post)
What is preeclampsia? According to the World Health Organization (WHO), one in ten pregnant women is affected by hypertensive disorders, and preeclampsia a
Transfection: A Comprehensive Guide (Post)Transfection protocols play a crucial role in the realm of molecular biology and genetic research, enabling the introduction of foreign nucleic acids into living cells. This innovati
In Vitro vs In Vivo: Key Differences & When to Use Each(Post)In Vitro vs In Vivo: Complete Comparison + Selection Guide | Research MethodsDiscover the distinct roles of 'In Vivo' and 'In Vitro' in biological research, where one offers a natural con
Types of ELISA: Direct, Indirect, Sandwich & Competitive Compared(Post)Written by Seán Mac Fhearraigh, PhD • Updated: 19 May 2026 • ~9 min read Quick Answer The five main types of ELISA are sandwich, competitive, direct, indirect and multiplex. Sandwich ELISA is
The Complement System - pathways & function in the immune system(Post)The Complement System Function Gone are the days when the complement system was considered solely a companion of its impressive adaptive immune system counte
Metabolic Exhaustion: How Mitochondrial Dysfunction Sabotages CAR-T Cell Therapy in Solid Tumors(Post)Imagine engineering a patient's own immune cells into precision-guided missiles against cancer—cells that can seek out and destroy tumors with remarkable specificity. This is the promise of CAR-T cell
Biomarkers & Inflammatory markers of atherosclerosis(Post)As atherosclerosis is a complex inflammatory disease, there are many influential biomarkers that contribute to the disease’s progression as well as biomarkers from atherosclerosis related di
Beta Oxidation of Fatty Acids(Post)Metabolism · Biochemistry GuideBeta-Oxidation of Fatty AcidsBeta-oxidation is the mitochondrial pathway that breaks fatty acids down into acetyl-CoA for energy. This guide covers where it happen
The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes(Post)Cancer Biology · GeneticsTumour Suppressor Genes: Roles, Examples & CancerTumour suppressor genes are the brakes on cell growth — they restrain proliferation, repair damaged DNA and trigger apoptosis
The Environmental Shift: How Climate Change and Biodiversity Loss are Driving the Hantavirus Surge(Post)The year 2026 has brought an unsettling spotlight onto an old adversary: Hantavirus. What began as isolated cases has rapidly escalated into a multi-country surge, leaving scientists and public healt
Avoid Reagent Risk: Polyclonal vs Monoclonal Antibodies for Researchers(Post)For reproducible, isoform-specific detection, choose a monoclonal antibody; for robust detection across multiple epitopes or faster turnaround, choose a polyclonal antibody. The real tradeoff is epit
Phosphatases and PTP1B – Mini review(Post)IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signif
IgA Test – Normal Ranges, Results & What They Mean(Post)Clinical · Immunology Guide IgA Test: Normal Ranges, Results & What They Mean [2026] What the immunoglobulin A blood test measures, how result
Transformation Protocol – Sample Transformation Protocols(Post)Introduction Transformation of bacteria with plasmids is not only of note for bacterial studies but also can be used for gene expression studies in mammalian cells. Most plasmids are of bact
Bone Resorption: Process, Markers & Clinical Significance(Post)Unravel the complexities of bone resorption, a crucial biological process essential for skeletal health and calcium regulation, through the intricate roles of osteoclasts and osteoblasts. Ke
Microtubule and Mitosis review(Post)Introduction Microtubules are key components of the cytoskeleton and are composed of alpha and beta tubulin. These dimerise in a head to tail fashion to form 13 linear protofilaments.
Cell Death Pathways: Intrinsic vs Extrinsic Apoptosis Guide(Post)At Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis! Key Takeaways: Apoptosis is a programmed cell death process, vital for tissue
Innate Immunity: Components, Functions & First Line of Defence(Post)Immunology · Innate ImmunityInnate Immunity: Components, Functions & First Line of DefenceThe innate immune system is the body’s first line of defence — a fast, non-specific response built from physic
Denosumab: A Comprehensive Overview of Mechanism, Applications, and Research Advances(Post)Biologics · Bone MetabolismDenosumab: RANKL Inhibition, Clinical Applications and BiosimilarsDenosumab is a fully human monoclonal antibody against RANKL, the cytokine that drives osteoclast formation
microbiota & immune system signaling | Assay Genie(Post)You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming