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Cetuximab: A Revolutionary Drug in Cancer Therapy(Post)
Quick Facts About CetuximabWhat is Cetuximab?Cetuximab is a monoclonal antibody targeting the epidermal growth factor receptor (EGFR), widely used in cancer therapy.How does Cetuximab wor
Ulviprubart: A Breakthrough in Autoimmune Disease Treatment(Post)Quick Facts About UlviprubartWhat is Ulviprubart?Ulviprubart is an experimental complement inhibitor designed to modulate immune responses in autoimmune diseases.What is the mechanism of
IHC Guide(Page) Toll-Like Receptor (TLR) & Innate Sensing(Page) 8-OHdG/Creatinine Ratio Too High? Urine ELISA Troubleshooting(Post)Quick answer A researcher running an 8-OHdG ELISA and a creatinine ELISA on human urine got 8-OHdG/creatinine ratios in the hundreds, then the thousands, of ng/mg, far above the ~30–40
BDNF in inflammation and neuropathologies(Post)BDNF Overview Brain-derived neurotrophic factor (BDNF) is a central mediator of neuroplasticity, a term used to describe the ability of neurons
Androgenic steroid action in breast cancer(Post)By Rachel Bleach, PhD Student, RCSI By the age of 79 years, 1 in 14 women will develop breast cancer (Global Burden of Disease Cancer 2017). Beatson reported
What are MHC Class I and II molecules?(Post)What are MHC Class I molecules? The MHC class I is a glycoprotein that is expressed on all nucleated cells of the human body. MHC class I are important in disease defense against viruses, ba
Cell Signalling – Mini Review(Post)Cell Signalling Cell signalling pathways have an important role in integrating a plethora of extracellular and intracellular signals to produce a controlled optimal o
Microcalcifications in breast cancer: Novel insights into the molecular mechanism and functional consequences(Post)Shane O’Grady, PhD student, RCSI Cancer is a disease that will, unfortunately, touch all of our lives at some point, directly or indirectly. Despite decades
Codrituzumab: Unveiling Its Role in Cancer Research and Treatment(Post)What You Need to Know About CodrituzumabWhat is Codrituzumab?Codrituzumab is an investigational monoclonal antibody targeting CD47, an immune checkpoint that regulates immune responses i
Guselkumab: Advancing Psoriasis and Autoimmune Disease Research Through IL-23 Targeting(Post)Quick Facts About GuselkumabWhat is Guselkumab?Guselkumab is a biologic therapy that selectively targets the p19 subunit of interleukin-23 (IL-23), playing a critical role in inflammator
The PD-1 Pathway and Cancer Immunotherapy(Post)The initial identification of PD-1 as a potential target for cancer treatment occurred in the late 1990s and early 2000s through studies exploring the regulation of T-cell responses.
The role of IL-18 in health and disease(Post)Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II
Annexin V Assays(Page)Annexin V Apoptosis Assay Kits | Flow Cytometry Detection | Assay Genie
Tarextumab: Unlocking the Potential of Cancer Therapeutics(Post)Quick Facts About TarextumabWhat is Tarextumab?Tarextumab is a novel therapeutic antibody designed to target the Notch signaling pathway, which plays a crucial role in tumor progression
Lirilumab: Unlocking the Potential of Anti-KIR Therapy in Cancer Research(Post)Quick Facts About LirilumabWhat is Lirilumab?Lirilumab is an anti-KIR monoclonal antibody designed to enhance natural killer (NK) cell activity by blocking killer-cell immunoglobulin-lik
Treg Suppression and the IL-2 Axis: Pathway, Function and Assays(Post)Regulatory T cells cannot make the cytokine they depend on. FOXP3 represses the Il2 locus, so every Treg lives on IL-2 secreted by the conventional T cells it exists to restrain. That asymmetry expla
What is an Antigen?(Post)Antigen's are foreign molecules recognised by the immune system. Antigens can be protein, carbohydrate, lipid or nucleic acid molecules. Examples include viruses and bacteria as well as fr
Allorecognition, Transplant Rejection & GvHD(Page)Featured
Human CAT (Catalase) ELISA Kit (HUFI07676)
- Product Code:
- HUFI07676
- Detection Method:
- Sandwich ELISA, Double Antibody
- Sensitivity:
- 9.375 pg/mL
- Range:
- 15.625-1000 pg/mL
Human MICA ELISA Kit (HUFI00015)
- Product Code:
- HUFI00015
- Detection Method:
- Sandwich ELISA, Double Antibody
- Sensitivity:
- 46.875 pg/mL
- Range:
- 78.125-5000 pg/mL
Fatty Acid Oxidation (FAO) Assay Kit (BR00001)
- Product Code:
- BR00001
- Instrument:
- Microplate Reader
Anti-Mouse IFNAR-1 In Vivo Antibody - Low Endotoxin (IVMB0202)
- Product Code:
- IVMB0202
- Antibody Type:
- Functional-Grade In Vivo Antibody
- Clone:
- MAR1-5A3
- Protein:
- IFNAR1
- Isotype:
- Mouse IgG1
Anti-Mouse CD25 In Vivo Antibody - Low Endotoxin (IVMB0148)
- Product Code:
- IVMB0148
- Antibody Type:
- Functional-Grade In Vivo Antibody
- Clone:
- PC61
- Protein:
- CD25
- Isotype:
- Rat IgG1 lambda
Anti-Mouse NK1.1 In Vivo Antibody - Low Endotoxin (IVMB0100)
- Product Code:
- IVMB0100
- Antibody Type:
- Functional-Grade In Vivo Antibody
- Clone:
- PK136
- Protein:
- NK1.1
- Isotype:
- Mouse IgG2a kappa
Anti-Mouse PD-1 Antibody [RMP1-14] In Vivo-Low Endotoxin (IVMB0037)
- Product Code:
- IVMB0037
- Antibody Type:
- Functional-Grade In Vivo Antibody
- Clone:
- RMP1-14
- Protein:
- PD-1
- Isotype:
- Rat IgG2a kappa
LSAMP Rabbit Polyclonal Antibody (CAB14248)
- Product Code:
- CAB14248
- Antibody Type:
- Polyclonal Antibody
MCM4 Rabbit Polyclonal Antibody (CAB13513)
- Product Code:
- CAB13513
- Antibody Type:
- Polyclonal Antibody
VEGF Rabbit Polyclonal Antibody (CAB12303)
- Product Code:
- CAB12303
- Antibody Type:
- Polyclonal Antibody
MDA ELISA Kit (UNFI0048)
- Product Code:
- UNFI0048
- Detection Method:
- Competitive ELISA, Coated with Antigen
- Sensitivity:
- 4.688 ng/mL
- Range:
- 7.813-500 ng/mL
Dopamine ELISA Kit (UNFI0013)
- Product Code:
- UNFI0013
- Detection Method:
- Competitive ELISA, Coated with Antigen
- Sensitivity:
- 0.938 ng/mL
- Range:
- 1.563-100 ng/mL
Serotonin ELISA Kit (UNFI0018)
- Product Code:
- UNFI0018
- Detection Method:
- Competitive ELISA, Coated with Antigen
- Sensitivity:
- 0.938 ng/mL
- Range:
- 1.563-100 ng/mL
PGE2 ELISA Kit (UNFI0032)
- Product Code:
- UNFI0032
- Detection Method:
- Competitive ELISA, Coated with Antigen
- Sensitivity:
- 18.75 pg/mL
- Range:
- 31.25-2000 pg/mL
Human IL-6 ELISA Kit (HUFI00180)
- Product Code:
- HUFI00180
- Sensitivity:
- 2.813pg/ml
- Range:
- 4.688-300pg/ml
- ELISA Type:
- Sandwich
Glucose Assay Kit (BA0081)
- Product Code:
- BA0081
- Instrument:
- Microplate Reader