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TLX as a Novel Therapeutic Target(Post)
Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating ...
PhD Interview tips(Post)It’s not uncommon now for Masters or Undergraduate students to present some data or data that they produced during their research for a PhD interview process. Sometimes this can be in front of ...
The Brain's Sentinels: How Microglia Shape Neuroinflammation in Disease(Post)The Brain's Sentinels: How Microglia Shape Neuroinflammation in Disease In the intricate landscape of the human brain, a silent, ever-watchful guardian stands ready to defend against injury and inva ...
How to be a Confident Speaker (Scientific)(Post)Like needles in a haystack, interesting speakers that bring charisma and rock n roll to their talks are hard to come by. No matter what the research interests of the audience, these speakers h ...
How does Acute Myeloid Leukaemia start?(Post)I have been in the situation that I’m sure many of us have. I work on genes, which if you name to any right-minded individual, sound like a random string of nonsensical gibberish. So, mayb ...
AKT Signalling – Mini Review(Post)Protein kinase B or AKT (PKB) is a serine/threonine kinase. In mammals it is comprised of 3 highly homologous isoforms PKBα (Akt1), PKBβ (Akt2), and PKBγ (Akt3) (Manning and Cantley 2007). AKT ...
Tumour Inflammation & Signaling | Assay Genie(Post)By Charlotte O’Donnell PhD Inflammation and Cancer The link between inflammation and cancer is well established, with inf ...
The Ebola Virus: What You Need to Know(Post)The Ebola virus has been in the news a lot lately, but many people still don't know what it is or how it spreads. In this blog post, we will discuss the basics of the Ebola virus: w ...
BTLA: A Key Player in Immune Regulation and Cancer Therapy(Post)Introduction to BTLA in Immune Regulation B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that plays a critical role in regulating immune responses by suppress ...
Cancer Research Club March 2020(Post)ELISA Genie is delighted to announce the date of our next Cancer Research Club which will be taking place on the 31st of March at TTMI, Trinity College Dublin. This event will foc ...
Tezepelumab: A Breakthrough in Severe Asthma Treatment and Research(Post)Quick Facts About TezepelumabWhat is Tezepelumab?Tezepelumab is a monoclonal antibody designed to inhibit thymic stromal lymphopoietin (TSLP), a key driver of airway inflammation in sev ...
Compatibility and Performance Assessment of the GenieColor Mycoplasma Detection Kit Across Diverse Laboratory Conditions(Post)MORV0013 functioned effectively in both qPCR machines and water baths, with or without paraffin oil, maintaining consistent sensitivity and specificity. MORV0013 performed reliably betw ...
IgA Test – Normal Ranges, Results & What They Mean(Post)IgA Testing: Complete Diagnostic Guide + Interpretation Methods | Expert ProtocolsThe IgA test, also known as immunoglobulin A test, is a diagnostic tool used to measure the levels ...
4-1BB: Energizing Immune Cells to Overcome Tumor Resistance(Post)Immunotherapy has become a central pillar in the fight against cancer, with a focus on enhancing the body’s natural defenses. Among the molecules at the forefront of immunotherapeutic re ...
Embryonic Induced Pluripotent Stem Cell Differentiation: Pathways and Lineage-Specific Markers(Post)Embryonic induced pluripotent stem cells (iPSCs) hold immense potential in the field of regenerative medicine due to their ability to differentiate into various cell types. Understanding the diff ...
OKRs for Researchers(Post)Objectives & Key Results Objectives & Key Results (OKRs) is a framework for setting and tracking goals. At Assay Genie, we've tailored this approach to sui ...
The Lenti Viral Vector System: A New Way to Deliver Genetic Therapies(Post)A new way to deliver genetic therapies is making waves in the medical world. The lenti virus vector system has been shown to be more effective than traditional methods of gene thera ...
Do you know…migraines affect more than 10% of the world population?(Post)By Francisco Algaba Chueco In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge p ...
COVID-19(SARS-CoV-2)トリプレックスRT-qPCR検出キット| Assay Genie(Post)COVID-19(SARS-CoV-2)トリプレックスRT-qPCR検出キット COVID-19アッセイの概要: この製品は、新規コロナウイルスSARS-CoV-2によって引 ...
The Complement System - pathways & function in the immune system(Post)The Complement System Function Gone are the days when the complement system was considered solely a companion of its impressive adaptive immune system count ...
Natural Killer Cells: A Guide(Post)What are Natural Killer Cells? Natural Killer (NK) cells are a vital subset of lymphocytes, belonging to the same family as B cells and T cells, collectively known a ...
COVID-19 Rapid POC CE-IVDテスト(25テスト)| Assay Genie(Post)COVID-19 Rapid POC CE-IVDテスト(25テスト) 概要説明 Getein COVID-19 Rapid POC(臨床現場即時)キットは新型コロナウィルス ...
Platinum based cancer drugs and next generation therapeutics(Post)Platinum based cancer drugs Despite nearly 50% of all anti-cancer treatments being platinum-based, there is an urgent need to develop novel therapeutics ...
Filarial Infections - Tropical Diseases | Assay Genie(Post)By Juan Quintana, PhD student, University of Edinbrugh What are Neglected Tropical Diseases (NTDs)? The World Health Orga ...
Biological Role of GLP-1(Post)Glucagon-like peptide-1 (GLP-1) is a critical hormone in the regulation of glucose metabolism and has garnered significant attention due to its therapeutic potential in managing diabetes ...
EGFR Pathway and YAP in Non-Small Cell Lung Cancer(Post)Understanding the EGFR Pathway and YAP in Non-Small Cell Lung CancerThe epidermal growth factor receptor (EGFR) pathway plays a pivotal role in the development and progression of non-small cell lung ...
MAPK Signaling in Inflammatory Cytokines Pathways(Post)The Mitogen-Activated Protein Kinase (MAPK) pathway is a pivotal signaling cascade that plays a crucial role in mediating cellular responses to various external stimuli. This pathway is intricate ...
SOCS proteins: Manipulating the immune response(Post)Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types ...
Estrogen and Breast Cancer: a Nuclear (Receptor) War(Post)By Dr. Lisa Dwane, Postdoctoral Researcher, Royal College of Surgeons in Ireland The first link between estrogen and breast cancer was made in the ...
CD122: Fine-Tuning T Cell Responses in Immunotherapy(Post)Introduction to CD122 in Immunotherapy CD122, also known as the interleukin-2 receptor beta chain (IL-2Rβ), is a critical component of the immune system's response to pathogens and ...
TIM-3: Targeting T Cell Exhaustion for Better Immunotherapy Outcomes(Post)T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is an immune checkpoint receptor that plays a pivotal role in T cell exhaustion, a state where T cells lose their ability to e ...
Build a science blog to progress your career(Post)What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of ant ...
Biosimilar: Expanding Access to Monoclonal Antibody-Based Therapies(Post)1. What is a Biosimilar? A biosimilar is a biologic medical product that is highly similar to an already-approved reference biologic. While minor differences in clinically inactive ...
The role of key Interleukins(Post)Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hem ...
CD25 Marker(Post)CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...
Networking tips for scientists(Post)During my PhD I knew how networking was important, it helped me source reagents off other labs, get the best advice and helped me land a post doc at Cambridge University. Its not ...
Fluorescence Resonance Energy Transfer (FRET) Assays: An Insight into Molecular Interactions(Post)Fluorescence Resonance Energy Transfer (FRET) assays represent a pivotal technique in the molecular and cellular biology fields, enabling the examination of protein interactions, nucleic acid str ...
BDNF in inflammation and neuropathologies(Post)BDNF Overview Brain-derived neurotrophic factor (BDNF) is a central mediator of neuroplasticity, a term used to describe the ability of neuron ...
Platelet Adhesion Proteins and Ligands: Key Players in Hemostasis and Thrombosis(Post)Platelet adhesion is a critical process in the maintenance of hemostasis, the body's response to bleeding. This intricate process involves a series of interactions between platelets, the cellular ...
Unraveling the Mysteries of Platelet-Activating GPCR Signaling(Post)Platelet activation plays a pivotal role in hemostasis, the process that stops bleeding and initiates wound healing. Central to this process is the activation of G protein-coupled receptors (GPCR ...
Articular Cartilage Extracellular Matrix(Post)Articular cartilage, a key player in joint function, owes its unique properties to its extracellular matrix (ECM). This complex, highly specialized structure is not only fundamental in maintainin ...
Understanding Platelet Activation: A Comprehensive Overview(Post)Platelet activation plays a pivotal role in hemostasis, the process that stops bleeding and initiates tissue repair after vascular injury. This complex biological mechanism involves the transform ...
Inhibiting cell division(Post)Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surroundin ...
Blood Coagulation Pathway: Factors, Cascade & Disorders [Guide](Post)Blood Coagulation Pathways Blood clotting, also known as hemostasis, is a fascinating and intricate process that ensures our bodies can effectively respond to injuries and prevent excessive ...
Validation of MycoGenie Rapid Mycoplasma Detection Kit - A highly sensitive visual determination method for Mycoplasma detection.(Post)The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...
Typical Workflow of CRISPR-Cas9 Genome Editing(Post)The CRISPR-Cas9 system is a powerful tool for genome editing, enabling precise modifications to DNA. The typical CRISPR-Cas9 workflow involves several steps, from designing guide RNAs to ...
Deprotonation: Unveiling the Chemistry Behind It(Post)Deprotonation is a fundamental chemical process that plays a crucial role in various aspects of chemistry, ranging from organic synthesis to biochemistry. It involves the removal of a proton ( ...
29 PhD Thesis Writing Tips(Post)Explore 29 essential tips for crafting a compelling and well-structured PhD thesis, blending effective writing practices with time management and academic rigor for a successful dissertation jour ...
What are the stages of Parkinson's disease?(Post)What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...
Angiotensin Pathways: Unlocking the Secrets to Blood Pressure Regulation and Beyond(Post)The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...
CD73: Combating Tumor Immunosuppression by Targeting Adenosine(Post)Introduction to CD73 and Tumor Immunosuppression CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of various cells, including tumor cells and immune cells ...
Labeling Non-Antibody Proteins and Small Molecules: An Advanced Guide(Post)In the evolving landscape of biochemical research and diagnostic assay development, the ability to label non-antibody proteins and small molecules with high precision has become indispensable. Th ...
VEGF-A VEGFR-2 Signaling: Decoding the Blueprint of Angiogenesis for Therapeutic Insights(Post)The orchestration of angiogenesis, the process by which new blood vessels form from pre-existing ones, is a complex symphony regulated by various molecular players. At the forefront of this in ...
COVID-19 Workplace Testing(Post)Workplace Testing for COVID-19 Corporate Testing for COVID-19 The impact of COVID-19 on the econo ...
Wnt Signalling Pathway in Immunity(Post)What is Wnt Signalling? The Wnt signalling pathway is an evolutionarily conserved pathway that plays critical roles in the regulation of determining cell ...
Antigen Presenting Cells (APCs) and cancer immunotherapy(Post)Explore antigen presentation's crucial role in adaptive immunity and its impact on cancer immunotherapy, highlighting the diversity and function of MHC class I molecules. Key Takeawa ...
Targeting IL-10R: Enhancing Immune Activation in Cancer(Post)Introduction to IL-10R and Immune Suppression in CancerThe interleukin-10 receptor (IL-10R) is a key player in regulating immune responses, particularly in suppressing inflammation and m ...
Chronic myelogenous leukaemia (CML) – Review(Post)Chronic myelogenous leukaemia (CML) is a myeloproliferative haematopoietic malignancy, characterised by a karyotypic abnormality present in more than 95% of cases known as the Philadelp ...
Sensing Danger: The Biology of TLR-Mediated Inflammation(Post)By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...
Time-Resolved Fluorescence (TRF): A Comprehensive Introduction(Post)Time-Resolved Fluorescence (TRF) technology is a cutting-edge analytical technique that has revolutionized the fields of biochemistry, immunology, and molecular biology. By offering a refined app ...
Immunoglobulin Antibodies: Types, Structure & Clinical Uses(Post)Immunoglobulin antibodies stand at the forefront of the immune defense system, offering a sophisticated mechanism for recognizing and neutralizing a vast array of pathogens, including bacteria, ...
Innate Immune Systemc Explained: Step-by-Step Process & Key Concepts(Post)The innate immune system is the first line of defense against pathogens, providing a rapid response to infections. This system comprises various cell types, each with specialized roles in detecti ...
Chemokines versus Cytokines: A Detailed Comparative Study(Post)The complex interplay between chemokines and cytokines is fundamental to the immune system's function, orchestrating the body's response to infection, inflammation, and injury. This detailed anal ...
Governing the Fate of Stem Cells With Transcription Factors(Post)The intricate process of stem cell differentiation and self-renewal is a cornerstone of developmental biology and regenerative medicine. At the heart of this complex regulatory mechanism are tran ...
8 Steps to Mindfulness in the Laboratory(Post)Stress and anxiety are a normal part of our daily lives and impact everything we do from our relationships with loved ones to our performance in the laboratory. Like any scientist, I experienced ...
Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus(Post)Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus A groundbreaking study published in November 2025 has provided the most definitive evidence to date that the common ...
Flow Cytometry Gating: A Comprehensive Guide(Post)Flow cytometry gating is a critical step for isolating and analyzing specific cell populations based on size, granularity, and fluorescence. Proper gating strategies enhance data accurac ...
Hybridoma Technology: Revolutionizing Antibody Production(Post)Hybridoma technology, a revolutionary method in immunology pioneered by Georges Köhler and César Milstein in the 1970s, has transformed the landscape of antibody production. This groundbreaking t ...
CB6 Biosimilar: Targeting SARS-CoV-2 with Cost-Effective Monoclonal Antibody Therapy(Post)CB6, also known as Etesevimab, is a monoclonal antibody that targets the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. It neutralizes the virus by preventing it from bin ...
MHC Class I vs Class II: Key Differences & Functions [Guide](Post)Major Histocompatibility Complex (MHC) molecules are essential for immune recognition and response. They are specialized glycoproteins that present antigens to T cells, allowing the immu ...
Horseshoe Crab Blood and Endotoxin Testing: A Comprehensive Guide(Post)Horseshoe crabs, often referred to as "living fossils," are invaluable to modern medicine due to their unique blue blood. This blood is the source of Limulus Amebocyte Lysate (LAL), a su ...
M2 Supplement for Organoid Cell Culture: Enhancing Growth and Differentiation(Post)The use of M2 Supplement in organoid culture has revolutionized the way researchers cultivate and maintain these three-dimensional (3D) cellular models. Organoids—self-organizing cell cl ...
Histamine Receptors: Gatekeepers of Immunological and Neurological Responses(Post)Histamine, a biogenic amine, plays a crucial role in various physiological processes, including immune responses, gastric acid secretion, and neurotransmission. Central to the action of histamine ...
Toll-Like Receptor Signaling Pathways: A Key to Innate Immunity(Post)In the intricate landscape of the immune system, toll-like receptors (TLRs) play a fundamental role in the first line of defense against pathogens. These receptors, essential components of the in ...
Distributors(Page)At Assay Genie, we're proud to support scientists in acheiving their research goals around the globe! Working with the right distributors is an important part of achieving our mission. C ...
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Adipocytokines(Page)Adipocytokines or adipokines are bioactive molecules that are produced by adipose tissue. They comprise cytokines, chemokines coagulation factors and factors involved ...
COVID-19 Throat Swab Test(Page)COVID-19 Throat Swab Test Throat/Oropharyngeal Swabs for Viral Sample Collection The development of diagnostic tests for COVID- ...
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Cell-Based ELISA Kits (Page)Cell-Based ELISA Kits No More Western Blots! Over 1,600 Cell-Based ELISA kits to measure the relative levels of intracellular and phosphorylat ...
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Urea Assays(Page)Urea Assays At Assay Genie we've developed a range of Urea assays for researchers to analyse key steps in the Urea Pathway.
COVID 19 Nasal Swab Test(Page)COVID-19 Nasal Swab Test Nasal/Nasopharyngeal Swabs for Viral Sample Collection The developme ...
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Transcription Factor Activity Assay Kits(Page)Transcription Factor Assays Detect Transcription Factors via indirect ELISA methods! Detect transcription factors or study transcription fact ...
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IHC Guide(Page)Immunohistochemistry Protocol Guide Introduction Immunohistochemistry (IHC) is a technique widely used in histology and pathology ...
Multiplex Assays(Page)Multiplex Assays "It’s like doing 24 different ELISA in every well!" GeniePlex Multiplex Assays allow researchers to quantify up to 24 analytes in as little as 15μL of sample ...
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PharmaGenie ELISA Kits(Page)PharmaGenie ELISA Validated According to ISO Quality Systems Highly validated ELISA designed to exceed the needs of biopharma R&D s ...
Cell Culture Guide - Techniques and Protocols - Mandarin(Page)细胞培养指南——技术和方案 哺乳动物细胞组织培养技术指南。涵盖大量关于哺乳动物细胞系的维持、分裂和细胞保存的信息。请注意,所有细胞培养必须使用无菌技术在层流罩中进行。 1.引言 细胞培养是细胞和分子生物学中使用的关键工具,可以对细胞的生理学和生物 ...
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Anti-Tag Antibodies(Page)Anti-Tag Antibodies Highly Specific and Non-reactive Anti-Tag Antibodies Explore Anti-Tag Antibodies window.SHOGUN_IMAGE_ELEMENTS = window ...
SARS-CoV-2 Strains(Page)COVID-19 COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respiratory syndrome coronavirus 2. The most common abbrev ...
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