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    The Adenosine Axis: How CD39 and CD73 Switch Immunity Off(Post)

    The most abundant immunosuppressive molecule in a solid tumour is not a protein. It is adenosine — a metabolite, produced from ATP in two enzymatic steps, at concentrations orders of magnitude above

    Novel Gene Therapy for Cystic Fibrosis (Post)

    Novel Gene Therapies for Cystic Fibrosis Cystic Fibrosis Cystic fibrosis (CF) is an autosomal recessive, life-limiting disease resulting from gene mutations that encode the cystic fibr

    Fibroblast Markers(Post)

    Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix

    The Role of ACE2 in SARS-CoV-2(Post)

    Structure, Function, and Detection Assays for COVID-2019 Background The global spread of the novel cor

    Mycoplasma in Cell Culture Detection Guide(Post)

    As a PhD student delving deep into the realm of cellular biology, there is one antagonist that consistently challenges my research: mycoplasma. This microscopic bacterium, with its a

    Ce que doit valider tout chercheur sur les anticorps neutralisants(Post)

    Ce que doit valider tout chercheur sur les anticorps neutralisants Un anticorps neutralisant (AcN) bloque l’infectivité d’un agent pathogène en empêchant l’interaction fonctionnelle avec son récepteu

    The Strategic Role of Secondary Antibody Incubation Times in Immunodetection Techniques(Post)

    Immunodetection · ProtocolsSecondary Antibody Incubation: Times, Conditions and TroubleshootingThe secondary antibody step determines how much signal you get and how much background comes with it. Inc

    In the Thymus, Co-stimulation Kills(Post)

    In the periphery, co-stimulation rescues a T cell. In the thymus, the same molecules kill it. A peripheral T cell that engages its receptor without CD80 and CD86 becomes anergic; engage them and it r

    No Cytokine on This Pathway Touches Bone(Post)

    Not one immune cytokine on this pathway touches bone. TNF, IL-1β, IL-6 and IL-17A all act on osteoblasts, osteocytes and synovial fibroblasts, and it is those stromal cells that decide between RANKL

    Assay Genie launch SARS-CoV-2 qPCR assay(Post)

    SARS-CoV-2 qPCR assay from Assay Genie Assay Genie have just launched a qPCR assay for the detection of SARS-CoV-2. The SARS-CoV-2 One-Step RT-qPCR Kit for Coro

    Molecular Biology(Page)

    Molecular Biology Tools, PCR & Cloning Kits | Assay Genie

    10 Steps of Glycolysis: Enzymes, Diagram & ATP Yield(Post)

    Metabolism · Biochemistry Guide 10 Steps of Glycolysis: Enzymes, Diagram & ATP Yield The complete ten-step pathway that converts one glucose m

    Beta Oxidation of Fatty Acids(Post)

    Metabolism · Biochemistry GuideBeta-Oxidation of Fatty AcidsBeta-oxidation is the mitochondrial pathway that breaks fatty acids down into acetyl-CoA for energy. This guide covers where it happen

    The Notch Signalling Pathway: Its Steps and Impacts(Post)

    Notch signalling pathway review The Notch signalling pathway is a highly conserved intercellular signalling pathway that regulates various cellular processes. The Notch receptor is a transmem

    Site Directed Mutagenesis(Page)

    Site-Directed Mutagenesis | Protocol, Kits & Troubleshooting | Assay Genie

    Annexin V Assays(Page)

    Annexin V Apoptosis Assay Kits | Flow Cytometry Detection | Assay Genie

    Th17 and IL-23: Why Blocking IL-17 Sometimes Backfires(Post)

    Two drugs aimed at the same axis can give opposite results in the same disease. Blocking IL-23p19 is highly effective in psoriasis and works in Crohn’s disease. Blocking IL-17A directly is highly eff

    One Integrin Chain, Two Partners, Brain or Gut(Post)

    A chemokine gradient does not move a leukocyte anywhere. It only tells one that has already stopped which way to go. That sentence is the whole map. Trafficking is a four-step cascade and the steps a

    #LabChats with Laura Menke(Post)

    At ELISA Genie we are hugely interested in the future of science and we feel that PhD students are at the heart of this. Our new series, #LabChats, will see us interview different scienti

    Evita falsos positivos: isotipos y controles para investigadores(Post)

    Un isotipo es la clase de inmunoglobulina que define la región constante de su cadena pesada, y el organismo humano produce cinco: IgG, IgA, IgM, IgD e IgE. Cada uno tiene una forma distinta, apar