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A New Dawn in Cancer Treatment: Reprogramming the Immune System's Own Soldiers For decades, the fight against cancer has been a relentless battle of attrition, with treatments like chemotherapy and r

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The Immune System The immune system is a host defence system comprising many biological structures and processes within an organism that prot

Quick answer A researcher's colorimetric adenosine assay looked broken — the standard curve came out with a negative slope and the calculated values made no sense. The assay itself was

Immunoassays: ELISA, Multiplex & ELISpot Kits | Assay Genie

Imagine a high-stakes game of hide-and-seek where the seeker is your immune system and the hider is a master of disguise: cancer. For decades, we believed the 'wanted' posters for tumor cells were li

Testing for COVID-19 Since the start of the COVID-19 pandemic, the World Health Organisation have emphasised the crucial importance of

SARS-CoV-2, the causative viral agent of the novel coronavirus disease COVID-19, has sparked a global effort for creating prophylactic and therapeutic interventions. The following

AACR 2025: Meet Assay Genie at the American Association for Cancer Research Assay Genie is delighted to be attending and exhibiting at AACR 2025 in Chicago, Illinois from the 25-30th of

Spindle assembly checkpoint The spindle assembly checkpoint (SAC), or mitotic checkpoint, is the main cell cycle control mechanism that governs mitosis. Incorrec

Antibodies · Reagent GuideMonoclonal vs Polyclonal Antibodies: Key DifferencesMonoclonal and polyclonal antibodies are the two workhorse reagent types in research, diagnostics and therapy. Monoclonals

Immunology · Innate ImmunityInnate Immunity: Components, Functions & First Line of DefenceThe innate immune system is the body’s first line of defence — a fast, non-specific response built from physic

Hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers and there are 630,000 new cases diagnosed every year worldwide (De Minicis et al. 2013). HCC develops frequently fr

A T-cell engager does not give the T cell an instruction. It gives it an address. A bispecific antibody with one arm on CD3 and the other on a tumour antigen forces two membranes into contact and let

Not one immune cytokine on this pathway touches bone. TNF, IL-1β, IL-6 and IL-17A all act on osteoblasts, osteocytes and synovial fibroblasts, and it is those stromal cells that decide between RANKL

B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, play

Enzymology · Protein DegradationProtease vs Peptidase: Understanding the DifferenceProteases and peptidases are the enzymes that cleave peptide bonds — breaking proteins down into peptides and peptide

Quick Info Section: Key Facts About PlozalizumabWhat is Plozalizumab?Plozalizumab is an investigational monoclonal antibody that targets CD47, a key immune checkpoint in cancer cells. By