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Promising COVID-19 Therapeutics(Post)
SARS-CoV-2, the causative viral agent of the novel coronavirus disease COVID-19, has sparked a global effort for creating prophylactic and therapeutic interventions. The following
Lipid Metabolism Assays(Page)Lipid Metabolism Assay Kits | Cholesterol, Fatty Acids & Bile Acids | Assay Genie
Beyond Burnout: How T Cell Exhaustion Hijacks Cancer Immunity and What We Can Do About It(Post)Imagine a highly trained soldier, elite and effective, sent to the front lines of a relentless war. Day after day, they fight without rest, their supplies dwindle, and the enemy never stops coming. Ev
Cleaved Caspase-3 and Apoptosis(Post)Cell Death · BiomarkersCleaved Caspase-3: Activation, Function and Detection in ApoptosisCaspase-3 sits at the point where apoptotic signalling becomes irreversible. It is made as an inactive proenzym
Naratuximab: Redefining Cancer Therapy with Precision Medicine(Post)Quick Facts About NaratuximabWhat is Naratuximab?Naratuximab is an anti-CD37 monoclonal antibody-drug conjugate (ADC) designed to target B-cell malignancies, particularly non-Hodgkin lym
Schwann Cells: Specialized Cells that Support Nerve Function(Post)Schwann cells are cells that play a vital role in nerve function. They are responsible for myelinating axons and helping to ensure the transmission of electrical signals between neurons. Schwann c
Carbon Dioxide sensing in Immune Cells(Post)BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE Million years ago carbon dioxide (CO2) levels used to be conside
MAPK Signaling in Inflammatory Cytokines Pathways(Post)Cell Signalling · InflammationMAPK Signalling in Inflammatory Cytokine PathwaysMAPK cascades convert receptor engagement into changes in gene expression, and in inflammation they do it in both directi
IgE and Mast Cells: The Cell Is Armed in Advance(Post)The mast cell is loaded long before the allergen arrives. IgE bound to FcεRIα is not waiting to be recruited the way an antibody waits for antigen in a serum assay — it is already installed on the ce
Targeting USP22 to Boost Anticancer Immunity(Post)Targeting USP22: A New Approach to Enhance Anticancer Immunity Introduction In the ever-evolving landscape of cancer research, the intricate relationship between immune e
Decoding Parkinson's Disease: Insights into a Complex Neurological Disorder(Post)Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (slo
Investigating orthohantavirus infections with proteomics(Post)Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympto
Xeroderma pigmentosum: Causes, Inheritance, Treatment and Diagnosis(Post)What is Xeroderma Pigmentosum? Xeroderma pigmentosum (XP) also known De Sanctis-Cacchione syndrome is a rare genetic disorder that affects the skin, eyes and central nervous system. It is ca
Biomarkers in sepsis: Their Role in Early Detection and Management (Post)Sepsis, a life-threatening condition, is characterized by a dysregulated immune
COVID-19 Vaccine Candidates(Post)What is COVID-19 COVID-19, the disease caused by the coronavirus named SARS-CoV-2, first identified in Wuhan, China in December 2019 has spre
COVID-19 Antibody Testing(Post)COVID-19 Antibody Testing Antibody Production in COVID-19 COVID-19, the novel coronavirus disease
Belantamab: A Game-Changer in Multiple Myeloma Therapy(Post)Quick Facts About BelantamabWhat is Belantamab?Belantamab Mafodotin is a cutting-edge antibody-drug conjugate (ADC) designed for the treatment of relapsed or refractory multiple myeloma.
VEGF-A VEGFR-2 Signaling: Decoding the Blueprint of Angiogenesis for Therapeutic Insights(Post)The orchestration of angiogenesis, the process by which new blood vessels form from pre-existing ones, is a complex symphony regulated by various molecular players. At the forefront of this int
Pamrevlumab: Unveiling the Potential of Anti-Fibrotic Therapy in Clinical Trials and Research(Post)Quick Facts About PamrevlumabWhat is Pamrevlumab?Pamrevlumab (FG-3019) is a monoclonal antibody designed to target and inhibit the connective tissue growth factor (CTGF), a key driver of
Renal and Hepatic Function Assays(Post)Hepatic Function Assays Liver function assays are a suite of tests designed to assess the health and efficacy of our vital