10469 results for 'hmg coa reduc har'

HIV Virus: Replication Cycle and Pathogenesis in absence of HAART The human immunodeficiency virus (HIV) is a formidable pathogen that has posed a significant global

Immunodetection · ProtocolsSecondary Antibody Incubation: Times, Conditions and TroubleshootingThe secondary antibody step determines how much signal you get and how much background comes with it. Inc

You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming

By Francisco Algaba Chueco In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge physiol

Overview of Diabetes Mellitus Diabetes mellitus (DM) is a major epidemic that affects over 347 million people worldwide (Danaei et al. 2011). The World Hea

By Rachel Bleach, PhD Student, RCSI By the age of 79 years, 1 in 14 women will develop breast cancer (Global Burden of Disease Cancer 2017). Beatson reported

Estabilidad de anticuerpos: métodos, criterios y errores de interpretación La estabilidad de anticuerpos se confirma cruzando dos evidencias, nunca una sola: integridad físico-química (temperatura de

Katherine Edwards, PhD Student, Queen’s University Belfast Cytokines play a vital role in immune responses enabling cross-talk between different cell types a

By Juan Quintana, PhD student, University of Edinbrugh What are Neglected Tropical Diseases (NTDs)? The World Health Organ

Immunology · Innate ImmunityInnate Immunity: Components, Functions & First Line of DefenceThe innate immune system is the body’s first line of defence — a fast, non-specific response built from physic

Anticuerpos validados con KO y ensayo ortogonal para investigadores Un anticuerpo validado es aquel cuya especificidad y funcionalidad quedan demostradas para la aplicación experimental concreta en l

Immunology · Myeloid CellsGranulocytes: Neutrophils, Eosinophils and BasophilsGranulocytes are the leukocytes with cytoplasmic granules and lobed nuclei — neutrophils, eosinophils and basophils. They

Biotina en ELISA: qué mide el kit y cómo evitar interferencias Un ELISA de biotina cuantifica biotina libre, o biotina total según el diseño del kit, en matrices como suero, plasma, orina, leche o al

Anticuerpos para IHC: cómo validarlos y evitar falsos positivos Use anticuerpos con evidencia publicada en inmunohistoquímica y, siempre que sea posible, opte por monoclonales o recombinantes: ofrece

Cell Signalling · CytokinesJAK-STAT Signalling: Mechanism, Regulation and InhibitorsJAK-STAT is the shortest route from a cytokine outside the cell to a change in gene transcription — receptor engagem

Cell Culture · ProtocolsPassaging Hybridoma Cells: A Detailed GuideHybridomas are productive but temperamental. They grow in suspension, are sensitive to shear and to overgrowth, and — the problem tha

Microbiology · ProbioticsLactobacilli: Structure, Metabolism, Identification and Probiotic UseLactobacilli are lactic acid bacteria found in fermented foods and across the human gastrointestinal, oral

5 controles para validar anticuerpos para western blot en investigación Para un western blot fiable, use un anticuerpo primario con validación documentada para esta técnica, que reconozca preferentem

Problemas ELISA: guía práctica para diagnosticar y corregir fallos Ante un resultado inesperado, lo primero es revisar los controles: blanco, negativo, positivo y curva estándar. Si la curva es plana

Control positivo ELISA: qué es y por qué valida cada corrida Un control positivo en ELISA es una muestra conocida que contiene el analito buscado y confirma que reactivos, conjugado y sustrato funcio