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Exploring Cellular Senescence: Defining Cell Morphology, Aging & Cell Division(Post)
Introduction Cellular senescence is a fascinating phenomenon that plays a crucial role in the aging process and various age-related diseases. It is essential to explore the cellular
Trained Immunity: How Your Innate Immune System Learns and Remembers(Post)For decades, immunologists believed that only adaptive immunity—the sophisticated system of T cells and B cells—could form lasting memories of past infections. The innate immune system, our body's fir
TUNEL staining : The method of choice for measuring cell death(Post)Techniques · Apoptosis DetectionTUNEL Staining: The Method of Choice for Measuring Cell DeathTUNEL staining is a gold-standard technique for detecting apoptosis in situ. By labelling the fragmented DN
B7-H3: A Promising New Target in Tumor Immunotherapy(Post)B7-H3, also known as CD276, is a member of the B7 family of immune checkpoint molecules that has emerged as a compelling target in tumor immunotherapy. Initially recognized for its role i
Growth Factors: Key Players in Biological Processes(Post)Cell Signalling · Growth FactorsGrowth Factors: Families, Receptors and Signalling PathwaysGrowth factors are secreted proteins that instruct cells whether to divide, differentiate, migrate or survive
KIR Blockade: Empowering NK Cells for Superior Tumor Clearance(Post)Introduction to KIR Blockade in Cancer ImmunotherapyNatural killer (NK) cells are crucial components of the innate immune system, responsible for recognizing and destroying virally infec
mRNA-1010 and Beyond: How Moderna's mRNA Platform is Revolutionizing Hantavirus Vaccine Development(Post)Hantavirus, a silent threat lurking in rodent populations, has long posed a significant public health challenge with its severe and often fatal outcomes. For decades, the quest for effective vaccines
T Helper Cells: Th1, Th2, Th17 Differences & Functions(Post)Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions - Your Ultimate Resource from Assay GenieIn this guide, we will explore the differences between TH1 and TH2 cells, their crucial r
CRISPR-Powered Light Sensors: A New Frontier in Ultra-Sensitive Cancer Detection(Post)Cancer detection often relies on advanced imaging or invasive procedures, frequently catching the disease at later, more challenging stages. Imagine a future where a simple, non-invasive test could s
B Cells: Function, Types, Activation & Role in Immunity(Post)B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, play
Coeliac Disease Signaling – Review | Assay Genie(Post)By Ciara Coleman PhD General Introduction Coeliac Disease (CD) is defined as a common, chronic inflammatory disease
Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions(Post)The Th1 Pathway In this guide, we will explore the differences between TH1 and TH2 cells, their crucial roles in the immune system, and the contributions of cytokines and transcription f
Mouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous Routes(Post)In Vivo Methods · ProtocolsMouse Injection Guide: Intraperitoneal, Subcutaneous, Intramuscular & Intravenous RoutesRoute choice and injection technique determine how much of a dose actually reaches it
CD73: Combating Tumor Immunosuppression by Targeting Adenosine(Post)Introduction to CD73 and Tumor Immunosuppression CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of various cells, including tumor cells and immune cells. It p
NLRP3 Inflammasome and Pyroptosis: Pathway, Function and Assays(Post)The inflammasome is one of the few innate pathways that destroys the cell it activates. A macrophage that assembles NLRP3 has committed to a decision it cannot reverse: a priming signal through TLR4
Scicomm (Science Communication) tips for beginners! (Post)Science communication (Scicomm) is currently on the up. As rebellion against the increasing distrust of science stemmed from bigoted and ignorant leaders, scientists are turning to s
Validated GeniePlex Panels(Page) Insulin Signaling and RTK: An Overview(Post)Cell Signalling · MetabolismInsulin Signalling & Receptor Tyrosine KinasesInsulin controls metabolism and growth through the insulin receptor — a receptor tyrosine kinase that branches into the
GPCRs (G Protein Coupled Receptors): A Guide(Post)Cell Signalling · Receptor BiologyGPCRs (G Protein-Coupled Receptors): A Complete GuideG protein-coupled receptors are the largest family of cell-surface receptors in the human genome and the ta
Toll-like Receptor Signalling in Neurodegenerative Disease(Post)Toll-Like Receptors The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathogen