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    Renal and Hepatic Function Assays(Post)

    Hepatic Function Assays Liver function assays are a suite of tests designed to assess the health and efficacy of our vital

    Co-Inhibitory Checkpoints Beyond PD-1: CTLA-4, LAG-3 and TIM-3(Post)

    PD-1 gets the attention, but it is one brake among many — and the others do not work the same way. The co-inhibitory receptors are routinely drawn as interchangeable stop signs on a T cell. They are

    How we can target the underlying immune processes in pathological inflammation in obesity, cancer and liver disease.(Post)

    Dr. Melissa Conroy, TTMI I am an immunologist and senior research fellow in the Cancer Immunology and Immunotherapy Group, Department of Surgery at Trinity

    Macrophage, M1 & M2, Polarization and Function(Post)

    What is a Macrophage? Macrophages are indeed a type of phagocyte, responsible for engulfing and destroying foreign particles and cellular debris. They are larger cells with more cytoplasm an

    CD8+ T Cells: Understanding the Role of Cytotoxic T Cells in Immunity(Post)

    Immunology · T LymphocytesCD8+ T Cells: Cytotoxic Mechanisms, Memory and ExhaustionCD8+ T cells kill infected and transformed cells directly, and they do it with a specificity nothing else in the immu

    Spotlight on Mitochondria(Post)

    Throughout my graduate and postgraduate studies I have been really intrigued and fascinated by the mitochondria, the organelle that keeps all of us running everyday! The more I learn about

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in imm

    Neutrophils - Cells of the Immune System(Post)

    The immune system is the body’s main defence against infection. In order to function properly, the immune system must be able to detect and protect against infinite agents such as

    3 Reasons to Publish in Open Access Journals(Post)

    Over the past few years momentum has gained in the scientific publishing community for researchers to publish their data in open access scientific journals. Open access to published research of

    Anti-CTLA-4 Immunotherapy(Post)

    CD Markers Cluster of Differentiation (CD) markers play an important role in the differentiation of B cells, T cells and NK (natural killer) ce

    Microglia and Neuroinflammation(Page)

    Cyclins and Cyclin Dependent Kinase – Review(Post)

    Cell Cycle · KinasesCyclins and Cyclin-Dependent Kinases: Regulation, Substrates and Mitotic ControlCDKs are inactive on their own. They require a cyclin partner, and because cyclin levels rise and fa

    VEGF: Inflammation and Tumourigenesis(Post)

    What is VEGF? Vascular Endothelial Growth Factors (VEGFs) are a group of homodimeric polypeptides, and are master regulators of vascular development, maintenance and a

    AKT Signalling – Mini Review(Post)

    Protein kinase B or AKT (PKB) is a serine/threonine kinase. In mammals it is comprised of 3 highly homologous isoforms PKBα (Akt1), PKBβ (Akt2), and PKBγ (Akt3) (Manning and Cantley 2007). AKT

    Sample Dilution Range Calculation for Competitive ELISA kits(Post)

    Quick answer A competitive ELISA is running correctly when the blank (zero standard) gives the highest OD, the standard curve drops smoothly with rising concentration, and your samples land in the

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and

    HIF Repress Pathways: An Insight into Cellular Oxygen Homeostasis(Post)

    Hypoxia-inducible factors (HIFs) are pivotal in the cellular response to oxygen deprivation. These transcription factors regulate various aspects of cellular and systemic homeostasis in response t

    Positive Control vs Negative Control(Post)

    T cell activation is a crucial process in the immune response, playing a pivotal role in how the body responds to pathogens and maintains immune homeostasis. This intricate process involves severa

    OKRs for Researchers(Post)

    Objectives & Key Results Objectives & Key Results (OKRs) is a framework for setting and tracking goals. At Assay Genie, we've tailored this approach to suit researc

    Antibody Conjugation: Techniques and Applications(Post)

    Antibody conjugation is a pivotal technique in biomedical research and diagnostic applications. This process involves the covalent attachment of a molecule, such as a drug, toxin, enzym