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    Glucose Assay Saliva Troubleshooting: Fixing Low Readings(Post)

    Quick answer A researcher measuring glucose in human saliva on the fluorometric procedure of a glucose assay kit had a textbook standard curve, yet every sample read far below the expe

    Cancer Research Club March 2020(Post)

    ELISA Genie is delighted to announce the date of our next Cancer Research Club which will be taking place on the 31st of March at TTMI, Trinity College Dublin. This event will focu

    3 Reasons to Publish in Open Access Journals(Post)

    Over the past few years momentum has gained in the scientific publishing community for researchers to publish their data in open access scientific journals. Open access to published research of

    Phosphatases and PTP1B – Mini review(Post)

    IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signif

    Cancer Metabolism: Tumorigenesis, Metabolic Therapy & The Warburg Effect(Post)

    Cancer Metabolism is the mechanism by which cancer cells make energy in order for them to grow and spread. Even in the presence of oxygen, cancer cells increase glucose uptake and produce lactate,

    IQGAP1 signaling review(Post)

    IQGAP1: IQ-motif containing GTPase-activating-like protein-1 reviewIQ motif-containing GTPase-activating-like protein-1 (IQGAP1) is a 190 KDa protein that belongs to a conserved family of sc

    ELISA Plate-to-Plate OD Differences: Same-Lot Troubleshooting(Post)

    Quick answer When plates from the same lot give very different OD values, the cause is almost always a comparison problem, not a manufacturing problem. The three usual culprits are a t

    Clinical Pathology Labs List: Overview, Services, and Importance(Post)

    Clinical pathology labs play a crucial role in modern healthcare, providing critical diagnostic testing services for a wide array of diseases and conditions. These laboratories are design

    Filarial Infections - Tropical Diseases | Assay Genie(Post)

    By Juan Quintana, PhD student, University of Edinbrugh What are Neglected Tropical Diseases (NTDs)? The World Health Organ

    What Causes Acute Pancreatitis?(Post)

    Acute pancreatitis (AP) is a condition in which activated enzymes and inflammatory mediators released from the pancreas cause damage to the pancreas and surrounding tissues. AP is furt

    Unraveling the Synergy: How Growth Factors Cooperate to Promote Tumorigenesis(Post)

    In the intricate ballet of cellular communication and regulation, growth factors play pivotal roles in guiding the processes of cell growth, division, and differentiation. These proteins are essen

    Growth Factors Can Cooperate to Promote Tumorigenesis(Post)

    Introduction Tumorigenesis, the process by which normal cells transform into cancer cells, is a multifaceted and complex event influenced by various internal and external factors. Among the

    Hippo Pathway Review(Post)

    MST2/Hippo PathwayMammalian Sterile Twenty (MST) pathways have been identified as a homologue of the ste20 kinase from Saccharomyces cerevisiae (Creasy and Chernoff 1995). The MST2/Hippo pathway

    ELISA Troubleshooting: A Low Standard Curve and Samples Reading Off-Scale(Post)

    Quick answer On the Periaxin (PRX) ELISA, a researcher found every serum sample reading above the top standard — optical density (OD) around 2.8–3.0 at 450 nm, well beyond the highest

    Biofilms: The Bacteria Invaders You Can't Ignore(Post)

    If you've ever had a urinary tract infection, you know all about bacteria. These tiny organisms can invade your body and cause all sorts of problems. But what you may not know is tha

    ELISA Troubleshooting: High %CV at Low Standards(Post)

    QUICK ANSWER On a Human I-FABP/FABP2 ColorStep ELISA, the top of the standard curve looked perfect while the three lowest standards showed duplicate %CVs of 37–450% — because their op

    LAG-3: Revitalizing T Cells in Exhaustion for Combination Therapies(Post)

    Lymphocyte Activation Gene-3 (LAG-3) is an immune checkpoint receptor that plays a critical role in regulating T cell function. In recent years, LAG-3 has emerged as a potential target fo

    Inhibiting cell division(Post)

    Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surrounding

    Inflammation and the aging process(Post)

    by Ryan Wallis, PhD Aging and Disease Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely. This is the deva

    Biological Role of GLP-1(Post)

    Glucagon-like peptide-1 (GLP-1) is a critical hormone in the regulation of glucose metabolism and has garnered significant attention due to its therapeutic potential in managing diabetes