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IgE and Mast Cells: The Cell Is Armed in Advance(Post)
The mast cell is loaded long before the allergen arrives. IgE bound to FcεRIα is not waiting to be recruited the way an antibody waits for antigen in a serum assay — it is already installed on the ce
Delete Every Microglial Cell, Then Ask What Changed(Post)Block one receptor and more than 90% of the microglia in a mouse brain are dead within a week. Not impaired — gone. Stop the block and they come back, repopulating from the survivors within another w
Senescence, the SASP and Immunosurveillance(Page) Toll-Like Receptor Signaling Pathways: A Key to Innate Immunity(Post)In the intricate landscape of the immune system, toll-like receptors (TLRs) play a fundamental role in the first line of defense against pathogens. These receptors, essential components of the inn
Horseshoe Crab Blood and Endotoxin Testing: A Comprehensive Guide(Post)Horseshoe crabs, often referred to as "living fossils," are invaluable to modern medicine due to their unique blue blood. This blood is the source of Limulus Amebocyte Lysate (LAL), a sub
CB6 Biosimilar: Targeting SARS-CoV-2 with Cost-Effective Monoclonal Antibody Therapy(Post)CB6, also known as Etesevimab, is a monoclonal antibody that targets the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein. It neutralizes the virus by preventing it from bind
Your Th2 Phenotype Might Not Be a T Cell(Post)If your knockout showed a type 2 phenotype and you attributed it to Th2 cells, there is a reasonable chance you were looking at something else. Innate lymphoid cells run T-bet, GATA3 and RORγt — not
TLX as a Novel Therapeutic Target(Post)Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating
Influenza Hemagglutinin (HA) Subtypes and Flu Virus Strains: What You Need to Know(Post)The flu is a highly contagious virus that affects the respiratory system. It can cause fever, muscle aches, and coughing. In some cases, it can lead to more serious health complicati
Physiological Roles for IL-33 | Assay Genie(Post)By Charlotte O'Donnell PhD A role for IL-33 in Barrier Function and Epithelial Wound Healing
Unraveling the Synergy: How Growth Factors Cooperate to Promote Tumorigenesis(Post)In the intricate ballet of cellular communication and regulation, growth factors play pivotal roles in guiding the processes of cell growth, division, and differentiation. These proteins are essen
Interactive Pathway Diagrams(Page) TNF Receptor Superfamily: TNFR1 vs TNFR2(Page) Build a science blog to progress your career(Post)What do scientists consider their skill set when looking for jobs outside of academia? Mine where hard to sum. I was a PhD in cell biology. I could Western Blot, I had used thousands of anti
Phosphorylation: Types, ATP Synthesis & Cell Signalling [Guide](Post)Biochemistry · Cell SignallingPhosphorylation: Types, ATP Synthesis and Cell SignallingAdding a phosphate group is how cells both store energy and switch proteins on and off. The same chemistry underl
Granulocytes: Neutrophils, Eosinophils, Basophils & Mast Cells(Post)Immunology · Myeloid CellsGranulocytes: Neutrophils, Eosinophils and BasophilsGranulocytes are the leukocytes with cytoplasmic granules and lobed nuclei — neutrophils, eosinophils and basophils. They
Epigenetic Antibodies(Page)Epigenetic Antibodies | 81+ Histone Acetylation & Methylation Antibodies | Assay Genie
Introducing BioSymposia: The Gathering Place for Science(Post)Announcement · Powered by Assay GenieIntroducing BioSymposia: The Gathering Place for ScienceWe’re excited to announce the launch of BioSymposia, our new sister platform and a free home for scientific
The EGFR/HER Family: Dimerisation, Ligand Independence & Resistance(Page) Guide to Western Blot Sample Preparation(Post)Protein Analysis · ProtocolsWestern Blot Sample Preparation: A Practical GuideMost failed Western blots fail before the gel is loaded. Lysis buffer choice, inhibitor selection, accurate protein quanti