10453 results for 'colony stimulating factor'

Renal Cell Carcinoma (RCC) is the most common form of kidney cancer, originating in the lining of the proximal renal tubules. RCC accounts for approximately 90% of all kidney cancers and ...

Quick Facts About VolagidemabWhat is Volagidemab?Volagidemab is a glucagon-like peptide-1 (GLP-1) receptor antagonist designed to regulate glucose metabolism and energy homeostasis.How ...

Quick Facts About IndusatumabWhat is Indusatumab?Indusatumab is an experimental antibody therapy targeting CD47, a protein that enables cancer cells to evade immune destruction.How does ...

Quick Facts About AvizakimabWhat is Avizakimab?Avizakimab is a monoclonal antibody designed to target the CD47 protein, a key checkpoint in immune regulation, particularly in cancer the ...

Introduction T lymphocytes are type of white blood cell that plays a crucial role in the immune system. There are many different types of T cells, and it is important to be able to di ...

By Charlotte O'Donnell PhD Similar to IL-33, IL-36R ligands are involved in maintaining intestinal homeostasis. Analogous to IL-33, d is local ...

Discover the distinct roles of 'In Vivo' and 'In Vitro' in biological research, where one offers a natural context and the other precise control, both vital for scientific advancement.

By Diana-Madalina Stan, PhD student, University of Salford Disease Description Alzheimer’s disease (AD), the most common cause of dementia, is ...

Key Points Non-alcoholic fatty liver disease (NAF ...

At Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis! Key Takeaways: Apoptosis is a programmed cell death process, vital for tissu ...

Introduction to CD122 in Immunotherapy CD122, also known as the interleukin-2 receptor beta chain (IL-2Rβ), is a critical component of the immune system's response to pathogens and ...

B Cell Types, Antigen Recognition & Activation A comprehensive guide to B cells! Introduction B cells, a vital component of the immune system, ...

Ana Catarina Ferreira Psychiatric disorders, including anxiety and depression, are highly prevalent conditions and its incidence is expected to increase as ...

Understanding PIIINP Levels in Canine Liver FibrosisLiver fibrosis is a significant health concern in dogs, often leading to severe complications if not diagnosed and managed appropriately. This arti ...

Cell death is an essential aspect of cellular biology that plays a crucial role in development, homeostasis, and disease. In this blog, we try to focus on mechanisms and various typ ...

Understanding the EGFR Pathway and YAP in Non-Small Cell Lung CancerThe epidermal growth factor receptor (EGFR) pathway plays a pivotal role in the development and progression of non-small cell lung ...

Quick Facts About RuplizumabWhat is Ruplizumab?Ruplizumab is an investigational monoclonal antibody designed to target CD47, a protein that helps cancer cells evade immune detection.Wha ...

Esophageal cancer is a type of cancer that affects the esophagus, which is the tube that carries food and liquids from your mouth to your stomach. Esophageal cancer can cause many d ...

Nanosilver is the most commercialised nanoparticle routinely used for its antibacterial purposes in food preservation, cosmetic and health products such as medical devices and wound treatme ...

Fluorescence Resonance Energy Transfer (FRET) assays represent a pivotal technique in the molecular and cellular biology fields, enabling the examination of protein interactions, nucleic acid str ...

Non-Small Cell Lung Carcinoma (NSCLC) is the most common type of lung cancer, representing about 85% of all lung cancer cases. NSCLC includes several subtypes, with distinct biological c ...

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Apoptosis, or programmed cell death, is a fundamental process that plays a critical role in the development and maintenance of healthy tissues. Central to this process are caspases, a family of c ...

Platelet adhesion is a critical process in the maintenance of hemostasis, the body's response to bleeding. This intricate process involves a series of interactions between platelets, the cellular ...

By Ana Catarina Ferreira, PhD Candidate, Univeristy of Minho, Portugal Psychiatric disorders, including anxiety and depression, are highly prevalent co ...

You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming ...

What are Stem Cells? Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organism ...

Quick Facts About CetuximabWhat is Cetuximab?Cetuximab is a monoclonal antibody targeting the epidermal growth factor receptor (EGFR), widely used in cancer therapy.How does Cetuximab w ...

The MycoGenie Rapid Mycoplasma Detection Kit enables the detection of 28 Mycoplasma species in under 1 hour using a simple visual determination method, eliminating the need for expensiv ...

What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dun ...

The ERK signal transduction pathway stands as a fundamental mechanism in cellular biology, orchestrating a wide array of physiological processes, including cell division, differentiation, and sur ...

Alex Lloyd PhD Candidate, Dublin Institute of Technology Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular disease ...

A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many comple ...

Ubiquitin is a small, highly conserved protein found in eukaryotic cells that plays a crucial role in regulating various cellular processes. The process of ubiquitination involves the covalent at ...

Microglia Astrocytes Oligodendrocytes Glial ...

Quick Facts About UlocuplumabWhat is Ulocuplumab?Ulocuplumab is an investigational monoclonal antibody targeting CXCR4, a chemokine receptor involved in tumor progression and immune cel ...

Quick Info Section: Key Facts About TalquetamabWhat is Talquetamab?Talquetamab is a novel monoclonal antibody being developed for the treatment of multiple myeloma and other cancers. It ...

Flow Cytometry Protocol The meaning is in the name: Flow = in motion, Cyto = cells, Metry = measure. What is Flow Cytometry? Flow c ...

Antibiotic resistance is a growing problem in the world today. Antibiotics are becoming less and less effective as bacteria evolve to resist them. This poses a serious threat to hum ...

In Vitro vs In Vivo: Complete Comparison + Selection Guide | Research MethodsDiscover the distinct roles of 'In Vivo' and 'In Vitro' in biological research, where one offers a natural co ...

By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

Glucagon-like peptide-1 (GLP-1) is a critical hormone in the regulation of glucose metabolism and has garnered significant attention due to its therapeutic potential in managing diabetes ...

In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pr ...

The 2025 Nobel Prize in Physiology or Medicine has been awarded to a trio of scientists for their groundbreaking work on peripheral immune tolerance, a mechanism that prevents our immune system from ...

Introduction Claudins are a family of proteins that play a critical role in the formation of ...

CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...

Laura Menke PhD candidate, Queen Mary University of London Inflammation vs. Resolution Atherothrombosis is the leading cause of death worldwide ...

Delving into the intricate world of Mitotic Catastrophe, this blog unveils its critical role in cell division and cancer therapy, offering insights into its mechanisms and potential treatments ...

Acetylation, a chemical process characterized by the addition of an acetyl functional group to a molecule, stands as a cornerstone in both biochemical and biological landscapes. Its significan ...

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Mechanical forces are common in biological systems and dominate numerous perturbations that are relevant to human physiology and disease. Mechanobiology is a new field that evaluates the ef ...

HMGB1 Functional Overview High mobility group box 1 ( HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 a ...

By Ciara Coleman PhD General Introduction Coeliac Disease (CD) is defined as a common, chronic inflammatory di ...

Fluorescent proteins (FPs) have revolutionized the field of molecular and cellular biology, allowing scientists to visualize and track biological processes in live cells with unprecedented clarit ...

The prevalence of obesity and its associated metabolic disorders has risen dramatically in recent decades, presenting a significant global health challenge. Adipose tissue, once considered mer ...

RIG-I: Antiviral Properties in COVID-19 (SARS-CoV-2) Infection Key Points RIG-I is a cytosolic RNA ...

Mesenchymal stem cells (MSCs) have emerged as pivotal players in the realm of regenerative medicine due to their unique properties and versatile potential. Originally discovered in the bone marro ...

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Immune Regulation in COVID-19: Immunomodulatory Mechanisms against SARS-CoV-2 Infection What is COVID-19? ...

Western blotting remains a pivotal technique in the molecular biosciences for the detection, quantification, and analysis of proteins. Its utility spans numerous fields, including immunology, de ...

The year 2026 has brought an unsettling spotlight onto an old adversary: Hantavirus. What began as isolated cases has rapidly escalated into a multi-country surge, leaving scientists and public heal ...

Mouse monoclonal antibodies are a valuable tool in the biomedical field. They can be used for a variety of applications, from research to clinical diagnostics. In this blog post, we ...

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The angiotensin pathway is a pivotal hormonal system that plays a crucial role in regulating blood pressure and maintaining fluid and electrolyte balance within the body. This complex biochemical ...

by Ryan Wallis, PhD Aging and Disease Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely. This is the dev ...

By Catríona Dowling, Post-Doc, RCSI I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure ...

The Enteric Nervous system (ENS) is one of the largest subdivisions of the Peripheral Nervous System. This remarkable system is embedded between sheets of smooth muscle cells of the intestina ...

BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE Million years ago carbon dioxide (CO2) levels used to be consid ...

In the intricate landscape of the brain, cells constantly communicate, sending and receiving messages that govern our thoughts, memories, and movements. For decades, scientists believed this communic ...

Neuroscience · MicrobiomeUnderstanding the Gut-Brain AxisThe gut-brain axis is the dynamic, bidirectional communication system that links the gastrointestinal tract with the central nervous system. T ...

Introduction to FoxP3 and Regulatory T Cells in CancerFoxP3 (forkhead box P3) is a transcription factor critical for the development and function of regulatory T cells (Tregs), a special ...

p53, encoded by the TP53 gene on chromosome 17, is a fundamental protein safeguarding against tumor formation. It orchestrates cellular responses to DNA damage and stress, crucially managing cell ...

Ralitsa R. Madsen – University of Cambridge Metabolic Research Laboratories Each one of us is the result of an extraordinary developmental proce ...

IntroductionThe human kinome is estimated to contain 518 genes, in comparison to the estimated 180 genes that comprise the phosphatome (Arena et al., 2005). These kinase genes represent a signi ...

What is the blood-brain barrier? The Blood-brain barrier (BBB) is a system of vessels that acts as a structural and chemical barrier between the brain and the rest of the body's circul ...

Cell counting is an important part of many different scientific experiments, enabling researchers to gather crucial data about cell populations and their characteristics. In this step-by-s ...

What is Cystic Fibrosis? Cystic fibrosis (CF) is a genetic disorder that impairs the body's ability to produce sweat and thick mucus. CF causes mucus to build up in ...

Hepatic Function Assays Liver function assays are a suite of tests designed to assess the health and efficacy of our vita ...

The inception of induced pluripotent stem cells (iPSCs) has heralded a new dawn in the realm of biomedical research and regenerative medicine, setting the stage for groundbreaking advancements in ...

ILC2 - Function, Cytokines, and Role in Health and Disease A quick guide to IL2C ...

In the intricate landscape of cellular communication, lies a sophisticated ...

By Pietro Maria Bertelli, PhD Candidate, Queens University Belfast Introduction Eye complications are very frequent in patients with diabetes, a ...

Oesophageal Adenocarcinoma is on the rise globally affecting more than 450,000 people worldwide (Pennathur, Gibson et al. 2013). Once diagnosed overall 5-year survival ranges from 15 % to ...

Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis (IPF) is a chronic, irreversible and ultimately fatal disease characterized by pro ...

Understanding Myeloid Cell Networks in Cancer ImmunotherapyImmunotherapy has revolutionized cancer treatment, yet its effectiveness in re-establishing original immune responses post-therapy remains l ...

CD Markers Cluster of Differentiation (CD) markers play an important role in the differentiation of B cells, T cells and NK (natural killer) c ...

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Quick Facts About RamucirumabWhat is Ramucirumab?Ramucirumab is a monoclonal antibody that targets vascular endothelial growth factor receptor 2 (VEGFR-2), inhibiting angiogenesis, a pr ...

Ahmad Gazali PhD candidate, University of Eastern Finland Type 1 diabetes (T1D) is an autoimmune disease where the pancreatic β cells that produce insulin, a key hormone involve ...

Impact of COVID-19 on Brain Aging and Cognitive DeclineThe COVID-19 pandemic has had profound effects on various aspects of human health, including mental health. A recent study involving nearly 1,00 ...

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What is DNA Polymerase Fidelity? The fidelity of a DNA polymerase is the result of accurate replication of a desired template. The fidelity of DNA polymerase ...

ELISpot 400x more sensitive than ELISA! Detection & Visualisation at the Single-Cell Level Explore ELISpot ...

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