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Obinutuzumab: Advancing Targeted Therapy in Hematologic Cancers(Post)
Quick Facts About ObinutuzumabWhat is Obinutuzumab?Obinutuzumab is a monoclonal antibody targeting CD20, primarily used in treating B-cell malignancies such as chronic lymphocytic leukem
PD-1/PD-L1 Checkpoint Signalling: Pathway, Function and Assays(Post)PD-1 does not switch a T cell off; it moves the threshold. Engagement of PD-1 by PD-L1 recruits a single phosphatase into the immunological synapse, and that one recruitment event is enough to collap
Assay Genie Sustainability Policy(Page) Prostate Cancer Markers : What to Look for in Your Test Results(Post)In this blog post, we will review prostate cancer markers and what you should look for in your results. Prostate antigen marker (PSA) and p63 are the most common markers found in pro
Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus(Post)Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus A groundbreaking study published in November 2025 has provided the most definitive evidence to date that the common E
One Ligand, Two Receptors, Opposite Jobs: TNFR1 vs TNFR2(Post)Blocking TNF cures rheumatoid arthritis in some patients and triggers demyelination in others. That is not a dosing problem, and it is not a patient-selection problem. It is the direct consequence of
Localised Resources(Page)Localised Resources in Multiple Languages | Assay Genie
Immunophenotyping by Flow Cytometry and Cell Type Markers(Post)Immunophenotyping by Flow Cytometry Immunophenotyping is a technique used in the field of immunology and cell biology to identify and classify cells based on the specific proteins o
Unraveling the Complexity of the Notch Signaling Pathway: A Key Player in Development and Disease(Post)The Notch signaling pathway is a highly conserved cellular communication system that plays a crucial role in various biological processes, including embryonic development, tissue homeostasis, a
2025 Nobel Prize in Medicine: Regulatory T Cells and Peripheral Immune Tolerance(Post)The 2025 Nobel Prize in Physiology or Medicine has been awarded to a trio of scientists for their groundbreaking work on peripheral immune tolerance, a mechanism that prevents our immune system from a
Bcell germinal centre pathway(Page) Cytokine Storms: What happens when the immune system overreacts?(Post)Immunology · HyperinflammationCytokine Storm and Cytokine Release Syndrome: Mechanisms, Triggers and MarkersA cytokine storm is a self-amplifying inflammatory response in which cytokine release drives
Targeting Immune Checkpoints as Cancer Therapy(Post)In recent years, the field of oncology has witnessed a paradigm shift with the advent of immunotherapy, a treatment modality that harnesses the body's immune system to combat cancer. Among the mos
Pancreatic Cancer and its Poor Prognosis(Post)Myrna Hurtado, PhD Student, University of North Texas Health Science Center Advancements in modern medicine have resulted in significantly prolonging and a
Hepatocyte growth factor (HGF) (Post)What is Hepatocyte Growth Factor? Hepatocyte growth factor (HGF) is a cytokine that is mainly produced by the liver. HGF is a pleiotrophic cytokine that regulates cell growth, motilit
LILT: A Novel Immune Checkpoint for Cancer Therapy(Post)Recent advances in immunotherapy have highlighted the importance of targeting immune checkpoints to enhance the immune system’s ability to combat cancer. A new potential target in this gr
Influenza Hemagglutinin (HA) Subtypes and Flu Virus Strains: What You Need to Know(Post)The flu is a highly contagious virus that affects the respiratory system. It can cause fever, muscle aches, and coughing. In some cases, it can lead to more serious health complicati
TNF cytokines and their Receptors(Post)The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cyt
Targeting Immune Checkpoints as Cancer Therapy(Post)The advent of immune checkpoint targeting marks a significant milestone in the oncological field, offering a beacon of hope for patients battling cancer. This innovative approach leverages the bod
Clinical Pathology Labs List: Overview, Services, and Importance(Post)Clinical pathology labs play a crucial role in modern healthcare, providing critical diagnostic testing services for a wide array of diseases and conditions. These laboratories are design