10614 results for 'IL-5'

A macrophage does not decide to eat; it counts votes. Every particle it touches carries a mixture of pro-phagocytic and inhibitory ligands, and engulfment follows only when the activating tally clear

Immunology · Myeloid CellsGranulocytes: Neutrophils, Eosinophils and BasophilsGranulocytes are the leukocytes with cytoplasmic granules and lobed nuclei — neutrophils, eosinophils and basophils. They

The T-cell receptor is the most finely calibrated detector in immunology. It must discriminate an agonist peptide present at a few dozen copies from a self peptide present at tens of thousands, and i

For decades, immunologists believed that only adaptive immunity—the sophisticated system of T cells and B cells—could form lasting memories of past infections. The innate immune system, our body's fir

Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a br

Immunology · Innate LymphocytesNatural Killer Cells: Receptors, Subsets and FunctionNK cells kill without prior sensitisation and without antigen-specific receptors, using a balance of activating and

By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLRs acco

Signal 1 tells a T cell what it is looking at; signal 2 tells it whether to care. The same peptide–MHC engagement that launches a productive effector response can just as easily install an anergy pro

Research Pulse · Data study Where biology is heading: what PubMed and 300,000 researcher visits reveal We compared five years of PubMed publication counts with two years of researcher visits to Assa

What is Immunometabolism? Immunometabolism is an exponentially growing, multi-disciplinary field of research aiming at deciphering the dynamic cellular and mole

Quick Facts About TezepelumabWhat is Tezepelumab?Tezepelumab is a monoclonal antibody designed to inhibit thymic stromal lymphopoietin (TSLP), a key driver of airway inflammation in seve