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10430 results for 'IFN-alpha 6/IFNA6'

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    The role of IFN gamma in inflammation, cancer and autoimmune disease(Post)

    Interferons are key cytokines in the immune system, crucial for combating viral and bacterial infections, with significant roles in both innate and adaptive immunity responses. Key Takeaways ...

    The Rise of Alpha-Emitting Radiopharmaceuticals: A New Era in Targeted Cancer Therapy(Post)

    Imagine a microscopic sniper, capable of delivering a lethal blow to a single cancer cell while leaving its healthy neighbors virtually untouched. This is the promise of targeted alpha therapy, a re ...

    Emapalumab: Unlocking the Potential of Targeting IFN-γ in HLH Treatment(Post)

    Quick Facts About EmapalumabWhat is Emapalumab?Emapalumab is a fully human monoclonal antibody that neutralizes interferon-gamma (IFN-γ). It is the first FDA-approved therapy for primar ...

    ​TNF alpha & Inflammation(Post)

    Delving into TNF alpha's critical role in inflammation and its therapeutic targeting. Key Takeaways: TNF alpha is a crucial cytokine in inflammation and apoptosis. Its structure facilita ...

    Interferons(Post)

    Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell survival and ...

    Biomarkers & Inflammatory markers of atherosclerosis(Post)

    As atherosclerosis is a complex inflammatory disease, there are many influential biomarkers that contribute to the disease’s progression as well as biomarkers from atherosclerosis related d ...

    The Rat Effectively Models Signature Cytokines of T Helper Cells(Post)

    Understanding the immune system's intricacies requires models that accurately reflect its complexity. The rat, as a model organism, plays a crucial role in immunological research, particularly i ...

    Litifilimab: A Promising Anti-BDCA2 Antibody for Lupus Treatment(Post)

    Quick Facts About LitifilimabWhat is Litifilimab?Litifilimab is a monoclonal antibody developed by Biogen targeting BDCA2, a receptor on plasmacytoid dendritic cells (pDCs), to regulate ...

    Siltuximab: Exploring IL-6 Inhibition in Castleman’s Disease and Research(Post)

    Quick Facts About SiltuximabWhat is Siltuximab?Siltuximab is a monoclonal antibody targeting interleukin-6 (IL-6), a cytokine involved in inflammation and immune regulation.What is the ...

    Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions(Post)

    window.SHOGUN_IMAGE_V2_ELEMENTS = window.SHOGUN_IMAGE_V2_ELEMENTS || new Array(); window.SHOGUN_IMAGE_V2_ELEMENTS.push({ uuid: 's-19118a5d-7dea-4fc9-8267-6237960845ca' }) The T ...

    Interleukin 12 (IL-12) in COVID-19 Vaccines(Post)

    Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

    T Helper Cells: Th1, Th2, Th17 Differences & Functions [2026](Post)

    Complete T Helper Cell Guide: Th1, Th2, Th17 & Functions - Your Ultimate Resource from Assay GenieIn this guide, we will explore the differences between TH1 and TH2 cells, their cruc ...

    Spanish Flu: The Deadliest Pandemic in History(Post)

    The Spanish flu pandemic of 1918-1919 was the deadliest in history. It is estimated that up to 100 million people died from the virus, which is more than three times the number who ...

    COVID-19 Biomarkers(Post)

    SARS-CoV-2 Background COVID-19 is characterised by a series of biological markers. In some instances, these biomarkers can be used as potent ...

    Adhesion molecules in atherosclerosis – ICAM1(Post)

    Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecule ...

    Neuroimmunology: The Immune System of the CNS(Post)

    What is Neuroimmunology? Neuroimmunology is a multidisciplinary scientific field dedicated to investigating the intricate and bidirectional interactions between the ...

    Dendritic Cells - Markers, Activation & Subtypes(Post)

    Exploring the multifaceted role of dendritic cells in immune function and disease. Key Takeaways DCs are professional antigen-presenting cells that capture, process, and pres ...

    Cytokine Storms: What happens when the immune system overreacts?(Post)

    Discover the critical role of cytokines as signaling molecules in immune responses, their functions, and the impact of their dysregulation, including cytokine storms. Key Takeaways: C ...

    The role of IL-18 in health and disease(Post)

    Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

    TNFRSF9: Enhancing Immune Cell Activity Against Tumors(Post)

    Introduction to TNFRSF9 and Its Role in Immune ActivationTNFRSF9, also known as 4-1BB or CD137, is a co-stimulatory receptor expressed on the surface of T cells, natural killer (NK) cell ...

    IL-10 signalling and regulation(Post)

    Explore the complexities of Interleukin-10 (IL-10) signaling and regulation, a crucial aspect in immune response modulation and its dual roles in cancer development and therapy. Key Takeaways ...

    Innate Viral Immunity & RIG-I in COVID-19(Post)

    RIG-I: Antiviral Properties in COVID-19 (SARS-CoV-2) Infection Key Points RIG-I is a cytosolic RNA ...

    Sensing Danger: The Biology of TLR-Mediated Inflammation(Post)

    By Eoin Mac Réamoinn Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLR ...

    MAPK Signaling in Inflammatory Cytokines Pathways(Post)

    The Mitogen-Activated Protein Kinase (MAPK) pathway is a pivotal signaling cascade that plays a crucial role in mediating cellular responses to various external stimuli. This pathway is intricate ...

    Anti-PD-L1: Targeting Tumor Evasion with Immune Checkpoint Blockade(Post)

    IntroductionCancer cells have developed sophisticated mechanisms to evade the immune system, particularly through the inhibition of T-cell responses. One such mechanism involves the prog ...

    Fenofibrate Usage for Diabetes Damage(Post)

    Fenofibrate, also known as FEN, is a drug that is used to lower cholesterol levels. It works by blocking the absorption of dietary cholesterol in the small intestine and therefore, re ...

    CXCL16 – Review(Post)

    CXCL16 CXCL16, a unique member of the CXC chemokine family, stands at the crossroads of immune modulation and vascular biology. Initially discovered as a che ...

    EGF Family (Post)

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

    Macrophage, M1 & M2, Polarization and Function(Post)

    What is a Macrophage? Macrophages are indeed a type of phagocyte, responsible for engulfing and destroying foreign particles and cellular debris. They are larger cells with more cytoplasm a ...

    Iscalimab: Advancing Research in Autoimmune Diseases and Transplantation(Post)

    What You Need to Know About IscalimabWhat is Iscalimab?Iscalimab (CFZ533) is a monoclonal antibody targeting CD40, a key protein involved in immune system regulation.What is the mechani ...

    Th17 Cell Differentiation: Insights into Immunological Dynamics(Post)

    Th17 cells, a subset of T helper cells characterized by their production of interleukin-17 (IL-17), play a significant role in the immune system's response to pathogens and in the pathology of a ...

    The role of key Interleukins(Post)

    Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hem ...

    Chemokines versus Cytokines: A Detailed Comparative Study(Post)

    The complex interplay between chemokines and cytokines is fundamental to the immune system's function, orchestrating the body's response to infection, inflammation, and injury. This detailed anal ...

    4-1BB: Energizing Immune Cells to Overcome Tumor Resistance(Post)

    Immunotherapy has become a central pillar in the fight against cancer, with a focus on enhancing the body’s natural defenses. Among the molecules at the forefront of immunotherapeutic re ...

    CXC Chemokine Family(Post)

    In the realm of immunology, CXCL chemokines emerge as fascinating conductors. These small proteins, marked by their CXC motif, wield considerable influence over our immune responses and a r ...

    Hydroxychloroquine: Potential Treatment for COVID-19(Post)

    Hydroxychloroquine: Potential Treatment for COVID-19 What is Hydroxychloroquine? Hydroxychloroquine (HC ...

    Heterogeneity of Type 1 diabetes in children(Post)

    Ahmad Gazali PhD candidate, University of Eastern Finland Type 1 diabetes (T1D) is an autoimmune disease where the pancreatic β cells that produce insulin, a key hormone involve ...

    Tocilizumab (Actemra®) in COVID-19 Treatment(Post)

    Tocilizumab (Actemra®) in COVID-19 Treatment What is Tocilizumab? Tocilizumab, also called atlizumab, is an immunosuppres ...

    Toll-like Receptor Signalling in Neurodegenerative Disease(Post)

    Toll-Like Receptors The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathoge ...

    CD4+ T Cells: Unveiling the Role of Helper and Regulatory T Cells(Post)

    CD4+ T cells are central to the immune system, functioning as coordinators of immune responses and regulators of immune tolerance. These cells are divided into two primary subtypes: Help ...

    Natural Killer Cells: A Guide(Post)

    What are Natural Killer Cells? Natural Killer (NK) cells are a vital subset of lymphocytes, belonging to the same family as B cells and T cells, collectively known a ...

    CD28: Amplifying T Cell Responses for Better Tumor Clearance(Post)

    The CD28 molecule plays a crucial role in amplifying T cell activation, which is critical for mounting effective immune responses against tumors. By engaging with co-stimulatory molecule ...

    OX40 Agonists: Revitalizing the Immune Response in Cancer(Post)

    Cancer immunotherapy has revolutionized treatment options, offering strategies to harness the immune system to target and destroy tumors. One emerging area of interest is the use of OX40 ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    The IL-36 Subfamily | Expression, Function & Regulation(Post)

    By Charlotte O'Donnell PhD The genes of the IL-36 family members are located in a cluster on chromosome 2 [1]. All three activating ligands, IL-36α, IL-36β ...

    CD25 Marker(Post)

    CD25, a key molecule in immune regulation, is integral to the function of activated lymphocytes and regulatory T cells. It's central in mediating immune responses, with implications in autoimmune ...

    Gut Inflammation and Inflammatory Diseases (Post)

    What is Gut Inflammation? The gut, or gastrointestinal (GI) tract is a long tube that starts from the mouth and extends to the anus. It includes various organs suc ...

    Physiological Roles for IL-33 | Assay Genie(Post)

    By Charlotte O'Donnell PhD A role for IL-33 in Barrier Function and Epithelial Wound Healing ...

    Etigilimab: Unveiling the Role of Anti-TIGIT in Cancer Research(Post)

    Key Facts About EtigilimabWhat is Etigilimab?Etigilimab is an anti-TIGIT monoclonal antibody being studied for its potential role in cancer immunotherapy.What role does Etigilimab play ...

    Targeting IL-10R: Enhancing Immune Activation in Cancer(Post)

    Introduction to IL-10R and Immune Suppression in CancerThe interleukin-10 receptor (IL-10R) is a key player in regulating immune responses, particularly in suppressing inflammation and m ...

    Immune Regulation in COVID-19 (Post)

    Immune Regulation in COVID-19: Immunomodulatory Mechanisms against SARS-CoV-2 Infection What is COVID-19? ...

    Anifrolumab: Transforming Lupus Treatment with Targeted Immunotherapy(Post)

    Quick Facts About AnifrolumabWhat is Anifrolumab?Anifrolumab is a monoclonal antibody that targets the type I interferon receptor, playing a crucial role in treating systemic lupus eryt ...

    Cyclophosphamide Side Effects(Post)

    Ovarian cancer is a set of malignancies that start in the ovaries, as well as adjacent portions of the fallopian tubes and peritoneum. Women have two ovaries, one on each side of the ...

    Liposomal nanosilver encapsulation for cytotoxic assays(Post)

    Nanosilver is the most commercialised nanoparticle routinely used for its antibacterial purposes in food preservation, cosmetic and health products such as medical devices and wound treatme ...

    T Cell Types, Activation, Polarization & Function(Post)

    T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! window.SHOGUN_IMAGE_ELEMENTS = window.SHOGUN_IMAGE_ELEMENTS || new Array(); wi ...

    Non-Alcoholic Fatty Liver Disease (NAFLD) - Biomarkers(Post)

    Key Points Non-alcoholic fatty liver disease (NAF ...

    Comprehensive Guide to Mononuclear Cells(Post)

    Mononuclear cells, as the name suggests, refer to a group of white blood cells characterized by the presence of a single nucleus. Understanding the nature, function, and significanc ...

    TIM-3: Targeting T Cell Exhaustion for Better Immunotherapy Outcomes(Post)

    T cell immunoglobulin and mucin-domain containing-3 (TIM-3) is an immune checkpoint receptor that plays a pivotal role in T cell exhaustion, a state where T cells lose their ability to e ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

    What are the stages of Parkinson's disease?(Post)

    What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

    CD8+ T Cells: Understanding the Role of Cytotoxic T Cells in Immunity(Post)

    CD8+ T cells, also known as cytotoxic T lymphocytes (CTLs), are a critical component of the immune system. They play a vital role in defending the body against viral infections, intracel ...

    TLR4: Unraveling the Role of Inflammation in Cancer Progression(Post)

    Introduction to TLR4 and Cancer Toll-like receptor 4 (TLR4) is a key component of the innate immune system, primarily responsible for detecting infections and initiating inflammator ...

    Leukemia Inhibitory Factor (LIF)(Post)

    Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role in various physiological processes within the human body. It has gained significant attention in the field o ...

    Streptococcus pneumoniae: Pathogenesis, Diagnosis, and Treatment(Post)

    Streptococcus pneumoniae, commonly known as pneumococcus, is a Gram-positive, encapsulated bacterium that is a leading cause of respiratory and invasive diseases worldwide. It is part of ...

    Decoding Parkinson's Disease: Insights into a Complex Neurological Disorder(Post)

    Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (sl ...

    Adalimumab: Mechanism, Clinical Applications, and the Role of Biosimilars(Post)

    Quick Facts About AdalimumabWhat is Adalimumab?Adalimumab is a fully human monoclonal antibody designed to neutralize tumor necrosis factor-alpha (TNF-α), a key cytokine involved in inf ...

    ICOS: Stimulating the Immune System for Superior Cancer Therapy(Post)

    Immunotherapy has transformed the landscape of cancer treatment by leveraging the body’s immune system to target and destroy cancer cells. A key player in this process is Inducible T-cel ...

    SLAMF7: Activating Natural Killer Cells for Potent Anti-Cancer Responses(Post)

    Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells, ...

    IL-6 개요(Page)

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    COVID-19 Cytokine Storm Multiplex Assays(Page)

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    Rat Multiplex ELISA Panels(Page)

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    Pre-clinical & Large Animal Antibodies(Page)

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    ELISpot Assay Kits(Page)

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    High Sensitivity Cytokine ELISA Kits & Multiplex Panels(Page)

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    ELISA Sampler Packs(Page)

    ELISA Sampler Packs Based on thousands of citations and years of scientific endeavour, Assay Genie has developed ELISA Sampler Packs. An ELISA Sampler Pack is a ...

    PharmaGenie ELISA キット(Page)

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    Mouse Multiplex ELISA Panels(Page)

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    Multiplex Assays(Page)

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    Adipocytokines(Page)

    Adipocytokines or adipokines are bioactive molecules that are produced by adipose tissue. They comprise cytokines, chemokines coagulation factors and factors involved ...

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    Chemokines(Page)

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    Adaptive immune system molecules(Page)

    Co-stimulatory and Co-inhibitory Molecules in Adaptive Immunity The adaptive immune system is in part regulated by a vast array of co-stim ...

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