7570 results for 'inflammation'

Immunology · Complement SystemThe Alternative Complement PathwayThe alternative pathway is one of three routes that activate complement — an antibody-independent, always-on surveillance system d

Our Cancer Research Club symposium series continued on Wednesday afternoon, at Royal College of Surgeons (RCSI), Dublin, Ireland. The Bouchier-Hayes lecture theatre was at maximum capacity w

Immunology · HaematopoiesisMyeloid Lineage: Pioneers of Immune Cell DevelopmentThe myeloid lineage is one of the two great branches of haematopoiesis, generating the innate immune and blood cells — mo

The STING (Stimulator of Interferon Genes) pathway plays a pivotal role in the innate immune system's response to cancerous cells and DNA viruses. Exploiting this pathway through STING activators

Double-stranded DNA in the cytosol is always a mistake. A virus has uncoated, a mitochondrion has ruptured, a micronucleus has burst, or a chromosome has been broken and left unrepaired. cGAS treats

Progression of the JAK STAT Signalling Pathway Cellular communication is a complex network of molecular interactions that govern various physiological processes. Among the many signal

Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating

Immunology · Cell BiologyCells of the Innate Immune System: Types, Functions and MarkersThe innate immune system responds within minutes, without prior exposure, using cells that recognise conserved m

Imagine a future where the devastating impact of a stroke could be significantly mitigated, not just by managing symptoms, but by directly repairing the cellular machinery damaged during the event. T

Cell Biology · PathologyNecrosis: Types, Causes, Mechanisms and How It Is MeasuredNecrosis is cell death accompanied by membrane rupture and release of intracellular contents — which is what makes it

By Charlotte O'Donnell PhD The genes of the IL-36 family members are located in a cluster on chromosome 2 [1]. All three activating ligands, IL-36α, IL-36β a

Research Pulse · Data study Where biology is heading: what PubMed and 300,000 researcher visits reveal We compared five years of PubMed publication counts with two years of researcher visits to Assa

Neuroscience · Myelin BiologyA Quick Guide to MyelinMyelin is the lipid-rich insulating sheath wrapped around nerve axons. Made by oligodendrocytes in the central nervous system and Schwann cells in t

CD16, also known as FcγRIII (Fc gamma receptor III), plays a crucial role in the immune system, serving as a receptor for the Fc region of immunoglobulin G (IgG). This receptor is a key player in

Antibodies are a special class of Y shaped proteins that help guard your body from invading viruses and bacteria. They do this by either neutralizing the dangerous substance

Cell Signalling · Kinase CascadesMAPK Signaling: The Pathway of Mitogen StimulationThe mitogen-activated protein kinase (MAPK) pathway is one of the most important signalling cascades in biology, conv

Quick Facts About GuselkumabWhat is Guselkumab?Guselkumab is a biologic therapy that selectively targets the p19 subunit of interleukin-23 (IL-23), playing a critical role in inflammator