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By Shane Houston, PhD Candidate Queen’s University Belfast Cancer is an age old adversary of the human race. This out-of-control growth of abnormal cells has been a shadow over human health t

A depletion experiment is only as good as the depletion you can prove. Injecting a functional-grade antibody and assuming the population is gone is the most common failure mode in in vivo immunology.

V-domain Ig suppressor of T cell activation (VISTA) is an emerging immune checkpoint receptor that plays a key role in suppressing T cell activity within the tumor microenvironment (TME).

Tocilizumab reverses cytokine release syndrome within hours, and it never touches the cell that started it. That sentence contains the whole mechanism. The trigger is a T cell — engaged by a CAR, a b

Cell Signalling · Growth FactorsGrowth Factors: Families, Receptors and Signalling PathwaysGrowth factors are secreted proteins that instruct cells whether to divide, differentiate, migrate or survive

Microglia Astrocytes Oligodendrocytes Glial

The IgA test, also known as immunoglobulin A test, is a diagnostic tool used to measure the levels of IgA antibodies in the blood. Immunoglobulin A (IgA) is a type of antibody that plays a cruc

Immunology · HyperinflammationCytokine Storm and Cytokine Release Syndrome: Mechanisms, Triggers and MarkersA cytokine storm is a self-amplifying inflammatory response in which cytokine release drives

QuickStep ELISA Kits | 90-Minute 1-Wash Assays | Assay Genie

By Dr. Niclas Thomas “Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As far as

Quick answer A researcher preparing a Human IL-18 ELISA wasn't sure whether the protocol's “300-fold” HRP-Streptavidin step meant adding 40 µL of concentrat

Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hema

Quick Facts About CobolimabWhat is Cobolimab?Cobolimab is a monoclonal antibody that targets TIM-3, a checkpoint protein involved in immune regulation, especially in cancer and autoimmun

Metabolism · Biochemistry Guide Cellular Respiration: Stages, ATP Production & Pathway Guide How cells convert glucose and oxygen into ATP acr

If your knockout showed a type 2 phenotype and you attributed it to Th2 cells, there is a reasonable chance you were looking at something else. Innate lymphoid cells run T-bet, GATA3 and RORγt — not