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10496 results for 'CD117/c-kit'

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    Sepsis and Immune Dysregulation(Post)

    Exploring sepsis: a critical imbalance in the immune response to infection. Key Takeaways: Sepsis is a severe, immune-driven response to infection causing systemic inflammation and poten ...

    Understanding Radial Glial Cells: Insights into Neurodevelopmental Processes(Post)

    Radial glial cells are essential in shaping the nervous system, serving dual roles in neurogenesis and structural support during the brain's developmental stages. Key Takeaways: Rad ...

    HERV-K group of endogenous retroviruses and cancer(Post)

    In 2006, upon completion of the Human Genome Project, it was discovered that nearly 8% of the human genome is made up of viral DNA. These viral remnants are composed of ancient germ ...

    Pyroptosis: A Promising Target for Immunotherapy(Post)

    Pyroptosis is an immunogenic form of cell death, meaning that it triggers an immune response. This makes pyroptosis a potentially promising target for immunotherapies that aim to bo ...

    The Exciting Field of Stem Cell Research(Post)

    What are Stem Cells? Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organism ...

    Interleukin 12 (IL-12) in COVID-19 Vaccines(Post)

    Interleukin 12 in COVID-19 Prophylactics Interleukin 12 is a cytokine with wide-reaching effects in the innate and adaptive immune system. O ...

    RNA Extraction for COVID-19 Testing(Post)

    Testing for COVID-19 Since the start of the COVID-19 pandemic, the World Health Organisation have emphasised the crucial impor ...

    The role of key Interleukins(Post)

    Interleukin signaling is involved in a number of biological processes, including cell growth and differentiation, inflammation and immunity. Interleukins are glycoproteins which act on hem ...

    Microglial Functions Explained: Immunity, Inflammation & Neurodegeneration(Post)

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    Biomarkers in sepsis: Their Role in Early Detection and Management (Post)

    Sepsis, a life-threatening condition, is characterized by a dysregulated immun ...

    How Furin and ACE2 Interact with the Spike on SARS-CoV-2(Post)

    What is the Coronavirus Spike Protein? COVID-19, the newest coronavirus to gain international attention, is caused by severe acute respirato ...

    Prevention and Risk Mitigation: Strategies to Reduce Hantavirus Exposure in a Changing World(Post)

    As hantavirus cases continue to rise globally, the question becomes not just how to detect infections, but how to prevent them in the first place. Recent epidemiological investigations across Califo ...

    What is an Antigen?(Post)

    Antigen's are foreign molecules recognised by the immune system. Antigens can be protein, carbohydrate, lipid or nucleic acid molecules. Examples include viruses and bacteria as well as f ...

    The role of IL-18 in health and disease(Post)

    Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II ...

    COVID-19 Antibody Testing(Post)

    COVID-19 Antibody Testing Antibody Production in COVID-19 COVID-19, the novel coronavirus disease ...

    Assay Genie launch SARS-CoV-2 qPCR assay(Post)

    SARS-CoV-2 qPCR assay from Assay Genie Assay Genie have just launched a qPCR assay for the detection of SARS-CoV-2. The SARS-CoV-2 One-Step RT-qPCR Kit for Cor ...

    Dendritic Cells - Markers, Activation & Subtypes(Post)

    Exploring the multifaceted role of dendritic cells in immune function and disease. Key Takeaways DCs are professional antigen-presenting cells that capture, process, and pres ...

    EGF Family (Post)

    Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced ...

    Anti-CTLA-4 Immunotherapy(Post)

    CD Markers Cluster of Differentiation (CD) markers play an important role in the differentiation of B cells, T cells and NK (natural killer) c ...

    Understanding the Gut-Brain Axis(Post)

    Neuroscience · MicrobiomeUnderstanding the Gut-Brain AxisThe gut-brain axis is the dynamic, bidirectional communication system that links the gastrointestinal tract with the central nervous system. T ...

    A Comprehensive Overview of Cell Death(Post)

    Cell death is an essential aspect of cellular biology that plays a crucial role in development, homeostasis, and disease. In this blog, we try to focus on mechanisms and various typ ...

    3D Respiratory Organoids Cell Viability in a High-throughput 384-well Plate Assay(Post)

    The Assay Genie 3D Organoid Cell Viability Assay (AKES081) provided superior results compared to ThermoScientific PrestoBlue, maintaining over 100% viability at all time points in untre ...

    CRISPR-Cas Screening for Cell Viability(Post)

    Key Points Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a method of gene editing that uses ...

    10 Steps of Glycolysis: Enzymes, Diagram & ATP Yield(Post)

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    ​TNF alpha & Inflammation(Post)

    Immunology · Cytokine SignallingTNF-alpha and Inflammation: Structure, Signalling & TherapyTumour necrosis factor alpha (TNF-α) is one of the most important pro-inflammatory cytokines in the body ...

    Histamine Receptors: Gatekeepers of Immunological and Neurological Responses(Post)

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    What are the stages of Parkinson's disease?(Post)

    What is Parkinson’s disease? Parkinson's disease can be seen as a neurodegenerative disease because it is associated with the loss of nerve ce ...

    CD31: A Comprehensive Look at an Essential Biomarker(Post)

    What is CD31? CD31, also known as PECAM-1, was originally described as a cell surface antigen present on platelets and megakaryocytes. CD31 is ...

    3D Cell Culture: Assay Guide(Post)

    References Key Points Three-dimensional (3D) cell cultures are artificially-created environments in which cells are permitted to grow or interact with their surroundings in a 3D f ...

    Boiling Proteins for Western Blotting: Optimal Conditions and Best Practices(Post)

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    Adhesion molecules in atherosclerosis – ICAM1(Post)

    Adhesion Molecules Direct cell-cell interactions are maintained and regulated by cell adhesion molecules. The expression of adhesion molecule ...

    Carbon Dioxide sensing in Immune Cells(Post)

    BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE Million years ago carbon dioxide (CO2) levels used to be consid ...

    What is CAR T-cell therapy?(Post)

    CAR T-cell therapy CAR (Chimeric Antigen Receptor) T-cell Therapy is a type of cancer treatment. CAR T-cells are made in the laboratory and they have an artificially created receptor on th ...

    Immuno-Biomaterial Development | Assay Genie(Post)

    Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dun ...

    Astrocyte Markers: A Guide(Post)

    Explore the world of astrocytes, crucial star-shaped cells in the brain, and understand how specific markers help study their roles in neural health and disorders. Key Takeaways: As ...

    Transformation Protocol – Sample Transformation Protocols(Post)

    Introduction Transformation of bacteria with plasmids is not only of note for bacterial studies but also can be used for gene expression studies in mammalian cells. Most plasmids are of bac ...

    ELISA vs Western Blot: Which Technique Should You Choose?(Post)

    Written by Seán Mac Fhearraigh, PhD  •  Updated: 19 May 2026  •  ~9 min read Quick Answer ELISA and Western Blot are both antibody-based protein detection methods. ELISA is f ...

    TNF cytokines and their Receptors(Post)

    The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cy ...

    An Overview of the glycoprotein GM-CSF(Post)

    This article breaks down the glycoprotein Granulocyte-macrophage colony-stimulating factor (GM-CSF) detailing its structure, function and therapeutic uses. It also describes its role in im ...

    PCR Detection of COVID-19 (SARS-CoV-2)(Post)

    PCR Detection of COVID-19 (SARS-CoV-2) Contents Background Assay Information Sample Types   & ...

    Immuno Oncology: If cancer was a pathogen, would a vaccine be able to destroy it?(Post)

    Thanks to the great intuitions of brilliant scientists like Louis Pasteur, Edward Jenner, Robert Koch, Emil von Behring, Gaston Leon Ramon, Albert Sabin, Jonas Salk in the past century, the ...

    Comparison of Assay Genie Dual Luciferase Reporter Assay (MORV0010) vs Promega (E1910): Performance Evaluation of Quenching Efficiency and Auto-luminescence(Post)

    Both Assay Genie MORV0010 and Promega E1910 effectively quenched Firefly luciferase before Renilla detection, minimizing signal overlap. E1910 achieved 99.95% quenching efficiency, whil ...

    Freezing Stimulated T Cells: A Detailed Guide(Post)

    Cryopreservation of stimulated T cells is a common technique in immunology research, allowing for long-term storage while maintaining their functional viability. Stimulated T cells—espec ...

    Exosomes - Discovery, Cargo, Biogenesis & Functions(Post)

    by Ryan Wallis, PhD student, QMUL, Blizard Institute The microscopic world of cell biology was first explored by Robert Hooke in the 17th century and published in his work, Microgr ...

    mRNA-1010 and Beyond: How Moderna's mRNA Platform is Revolutionizing Hantavirus Vaccine Development(Post)

    Hantavirus, a silent threat lurking in rodent populations, has long posed a significant public health challenge with its severe and often fatal outcomes. For decades, the quest for effective vaccine ...

    How we can target the underlying immune processes in pathological inflammation in obesity, cancer and liver disease.(Post)

    Dr. Melissa Conroy, TTMI I am an immunologist and senior research fellow in the Cancer Immunology and Immunotherapy Group, Department of Surgery at Trinit ...

    TUNEL staining : The method of choice for measuring cell death(Post)

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    Leukemia Inhibitory Factor (LIF)(Post)

    Leukemia Inhibitory Factor (LIF) is a cytokine that plays a crucial role in various physiological processes within the human body. It has gained significant attention in the field o ...

    Understanding the Bcl-2 Pathway in Cancer Therapy(Post)

    Understanding the Bcl-2 Pathway: Implications for Cancer Therapy The Bcl-2 family of proteins plays a pivotal role in regulating apoptosis, a crucial process for maintaining cellula ...

    Cellular Respiration: Stages, ATP Production & Pathway Guide(Post)

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    A Quick Guide to Myelin(Post)

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    What is RNAi? All You Need to Know(Post)

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    Pyruvate dehydrogenase (PDH)(Post)

    Pyruvate dehydrogenase is a complex enzyme involved in the conversion of pyruvate, a product of glycolysis, into acetyl-CoA, a crucial molecule in energy production and intermediary ...

    Personalized Vaccines in Cancer Treatment: The Future of Immunotherapy(Post)

    What Are Personalized Cancer Vaccines? Personalized cancer vaccines are a cutting-edge approach in cancer treatment that are designed to activate a patient's immune s ...

    Promising COVID-19 Therapeutics(Post)

    SARS-CoV-2, the causative viral agent of the novel coronavirus disease COVID-19, has sparked a global effort for creating prophylactic and therapeutic interventions. The following ...

    Alternative Complement Pathway: Activation, Regulation, and Significance(Post)

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    Transmission of SARS-CoV-2 (COVID-19) via Droplets and Aerosols (Post)

    Transmission of SARS-CoV-2 (COVID-19) via Droplets and Aerosols What is COVID-19? COVID-19, the dise ...

    Gut Inflammation and Inflammatory Diseases (Post)

    What is Gut Inflammation? The gut, or gastrointestinal (GI) tract is a long tube that starts from the mouth and extends to the anus. It includes various organs suc ...

    The Battle of Antibiotics: Penicillin vs. Streptomycin(Post)

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    Data Science for Immunologists | Assay Genie(Post)

    By Dr. Niclas Thomas “Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As f ...

    The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes(Post)

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    Autophagy in Focus: Molecular Mechanisms and Functional Insights(Post)

    Autophagy, a fundamental cellular process, plays an indispensable role in maintaining cellular homeostasis and ensuring the efficient recycling of cellular components. Through this ...

    Coeliac Disease Signaling – Review | Assay Genie(Post)

    By Ciara Coleman PhD General Introduction Coeliac Disease (CD) is defined as a common, chronic inflammatory di ...

    15 Minute Qualitative COVID-19 Test | Assay Genie(Post)

    COVID-19 Testing Results in 15 Minutes Accurate detection of IgM and IgG patient-generated antibodies with the rapid, poin ...

    Food Safety & Analysis Assays(Page)

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    Clinical Chemistry Assays(Page)

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    Plant & Environmental Stress Assays(Page)

    Plant & Environmental Stress Assays Explore our range of assays to measure reactive oxygen species, proline, secondary metabolites & more in plant tissues.

    Enzyme Activity Assays(Page)

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    Cation and Inorganic Ion Assays(Page)

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    Amino Acid and Protein Assays(Page)

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    Disease and Pathways Tools(Page)

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    PharmaGenie ELISA Range(Page)

    PharmaGenie ELISA Kits High Quality ISO certified and validated ELISA Kits Sensitive down to the picogram for many analyt ...

    TCA Cycle Assays(Page)

    TCA/Krebs Cycle Assays At Assay Genie we've developed a range of TCA assays for researchers to analyse key steps in the Krebs/TCA/Citric Acid cycle pathway. Different Products ...

    Citations(Page)

    Product CitationsMore than 1,000 cited products in scientific journalsWe're not just any scientific company; our products have made waves in the scientific community. From groundbreaking ...

    ELISA மதிப்பீடு, கொள்கை, நெறிமுறைகள், முறைகள் மற்றும் கருவிகள்(Page)

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    ELISA バッファーとレシピ(Page)

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    세포 용해를위한 소니케이션(초음파 처리 분해) 프로토콜 (Page)

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    Mycoplasma Troubleshooting Tips & FAQ(Page)

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    Ferroptosis Assays(Page)

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    Molecular Biology(Page)

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    ELISA 분석법, 원리, 프로토콜, 방법 및 키트(Page)

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    Annexin V Assays(Page)

    Annexin V Apoptosis Assay Kits | Flow Cytometry Detection | Assay Genie /* Hide BigCommerce's default page title + breadcrumb wrapped around this content */ .page-heading,.

    एलिसा परीक्षण, सिद्धांत, प्रोटोकॉल, विधियाँ & किट(Page)

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    ELISA プレートのクリーニングのヒント(Page)

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    101 Dicas para Solução de Problemas do ELISA(Page)

    101 Dicas de Resolução de Problemas em ELISA | Resolver Sinal de Fundo Elevado, Ausência de Sinal e Mais | Assay Genie .page-heading,.page-title,.breadcrumbs,.breadcrumb-list,nav.breadcrumbs{display: ...

    101 sugerencias para solucionar problemas de ELISA(Page)

    101 consejos para la resolución de problemas en ELISA | Solucione fondo alto, ausencia de señal y más | Assay Genie .page-heading,.page-title,.breadcrumbs,.breadcrumb-list,nav.breadcrumbs{display:non ...

    Urea Assays(Page)

    Urea Assay Kits | Urea Cycle, Ammonia & Amino Acid Assays | Assay Genie /* Hide BigCommerce's default page title + breadcrumb wrapped around this content */ .page-heading,.pa ...

    DNA Ligation(Page)

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    The NLRP3 inflammasome & pyroptosis(Page)

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    TIGIT/DNAM-1/CD155 (PVR) Checkpoint Axis(Page)

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    Lipid Metabolism Assays(Page)

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    IHC Antibodies(Page)

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    CD4+ T-helper cell differentiation(Page)

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    Brochures and Flyers(Page)

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    NK cell activation & innate cytotoxicity(Page)

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    Co-Immunoprecipitation (co-IP) Protocol(Page)

    Co-immunoprecipitation Protocol A detailed guide of how Co-IP works, a step by step Co-IP protocol and some hints & tips for your Co-IP workflow! Introductio ...

    Cytokine neutralisation network(Page)

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    Myeloid reprogramming in the tumour microenvironment(Page)

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    엘리사 버퍼 및 레시피(Page)

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    In Vivo depletion atlas(Page)

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