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Dendritic Cells - Markers, Activation & Subtypes(Post)
Immunology · Antigen PresentationDendritic Cells: Markers, Activation and SubtypesDendritic cells are the professional antigen-presenting cells that decide whether an immune response happens at all. T
T cell Immunophenotyping - A Guide(Post)Immunology · Flow CytometryT Cell Immunophenotyping: Markers, Subsets and Panel DesignImmunophenotyping identifies cell populations by the proteins on their surface. For T cells that means resolving n
Diabetic Retinopathy: premature cellular senescence and microvascular dysfunction(Post)By Pietro Maria Bertelli, PhD Candidate, Queens University Belfast Introduction Eye complications are very frequent in patients with diabetes, and thi
Gut Homing and Tissue-Resident Memory: How T Cells Stay Put(Post)A T cell does not choose which tissue to defend. The tissue chose it, during priming. A naive T cell has no tropism at all; it acquires one from the dendritic cell that activates it, and the instruct
Mononuclear Phagocytes in Health and Disease(Post)Mononuclear phagocytes, essential in immunity and homeostasis, perform diverse roles from phagocytosis to tissue repair, influencing health and disease. Key Takeaways: Mononuclear p
The Complement System - pathways & function in the immune system(Post)The Complement System Function Gone are the days when the complement system was considered solely a companion of its impressive adaptive immune system counte
Cómo eliminar endotoxinas de proteínas recombinantes sin perder actividad biológica(Post)Cómo eliminar endotoxinas de proteínas recombinantes sin perder actividad biológica La forma más fiable de obtener proteínas recombinantes con niveles seguros de endotoxina es combinar medidas upstre
PD-1 & PD-L1 Inhibitors(Post)PD-1 & PD-L1 interaction between T-cells and tumour cells. What are PD-1 and PD-L1? PD-1, also known as programmed cell death 1, is a receptor expressed on t
The role of IL-18 in health and disease(Post)Exploring IL-18: A key cytokine in inflammation and disease. Key Takeaways: IL-18, a pro-inflammatory cytokine, plays a pivotal role in immune responses, particularly in inducing Type II
T Cell Types, Activation, Polarization & Function(Post)T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! Introduction T-cells, vital components of the immune system, encompass vari
Adaptive immune system molecules(Page) IL-10 신호 및 규제(Page) CAR-T Cell Signalling Pathway: Costimulation, Output and Assays(Post)A chimeric antigen receptor is a synthetic protein wired into a real signalling pathway. The extracellular half is an antibody fragment; everything below the membrane is borrowed from the T-cell rece
High-Fidelity DNA Polymerase(Page) The common characteristics of cancer | Assay Genie(Post)By Shane Houston, PhD Candidate Queen’s University Belfast Cancer is an age old adversary of the human race. This out-of-control growth of abnormal cells has been a shadow over human health t
Trained Immunity: Reprogramming Innate Immune Memory for Future Health(Post)What if our first line of immune defense, the innate immune system, could learn from past encounters to fight future battles more effectively? For decades, we believed this was the exclusive domain of
Tertiary Lymphoid Structures: The Body's Hidden Arsenals in the Fight Against Cancer(Post)Tertiary Lymphoid Structures: The Body's Hidden Arsenals in the Fight Against Cancer Imagine a battlefield within the body, where the immune system stands as the last line of defense against the rele
EGF Family (Post)Epidermal Growth Factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor epidermal growth factor receptor (EGFR) which triggers ligand-induced d
Exploring the Frontier of Immunotherapy: T Cell Expansion(Post)In the realm of immunotherapy, T cell expansion has emerged as a pivotal strategy, holding promise in the treatment of various diseases, particularly cancer. T cells are a critical component of
Evita falsos positivos: isotipos y controles para investigadores(Post)Un isotipo es la clase de inmunoglobulina que define la región constante de su cadena pesada, y el organismo humano produce cinco: IgG, IgA, IgM, IgD e IgE. Cada uno tiene una forma distinta, apar