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    Tumour Inflammation & Signaling | Assay Genie(Post)

    By Charlotte O’Donnell PhD Inflammation and Cancer The link between inflammation and cancer is well established, with infl

    Polyclonal Vs Monoclonal antibodies: Key features (Post)

    Antibodies · Reagent GuideMonoclonal vs Polyclonal Antibodies: Key DifferencesMonoclonal and polyclonal antibodies are the two workhorse reagent types in research, diagnostics and therapy. Monoclonals

    Myeloid Lineage: Pioneers of Immune Cell Production(Post)

    Immunology · HaematopoiesisMyeloid Lineage: Pioneers of Immune Cell DevelopmentThe myeloid lineage is one of the two great branches of haematopoiesis, generating the innate immune and blood cells — mo

    Targeting IL-10R: Enhancing Immune Activation in Cancer(Post)

    Introduction to IL-10R and Immune Suppression in CancerThe interleukin-10 receptor (IL-10R) is a key player in regulating immune responses, particularly in suppressing inflammation and ma

    microbiota & immune system signaling | Assay Genie(Post)

    You are only part human. In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes! It is becoming

    T Cell Types, Activation, Polarization & Function(Post)

    T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells! Introduction T-cells, vital components of the immune system, encompass vari

    A Quick Guide to Myelin(Post)

    Neuroscience · Myelin BiologyA Quick Guide to MyelinMyelin is the lipid-rich insulating sheath wrapped around nerve axons. Made by oligodendrocytes in the central nervous system and Schwann cells in t

    Inflammation and the aging process(Post)

    by Ryan Wallis, PhD Aging and Disease Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely. This is the deva

    Filarial Infections - Tropical Diseases | Assay Genie(Post)

    By Juan Quintana, PhD student, University of Edinbrugh What are Neglected Tropical Diseases (NTDs)? The World Health Organ

    Exosomes - Discovery, Cargo, Biogenesis & Functions(Post)

    by Ryan Wallis, PhD student, QMUL, Blizard Institute The microscopic world of cell biology was first explored by Robert Hooke in the 17th century and published in his work, Microgra

    Galectin Therapeutics(Post)

    Idiopathic Pulmonary Fibrosis Idiopathic Pulmonary Fibrosis (IPF) is a chronic, irreversible and ultimately fatal disease characterized by prog

    IL-10 signalling and regulation(Post)

    Explore the complexities of Interleukin-10 (IL-10) signaling and regulation, a crucial aspect in immune response modulation and its dual roles in cancer development and therapy. Key Takeaways:

    Cleaved Caspase-3 and Apoptosis(Post)

    Cell Death · BiomarkersCleaved Caspase-3: Activation, Function and Detection in ApoptosisCaspase-3 sits at the point where apoptotic signalling becomes irreversible. It is made as an inactive proenzym

    Calculer et valider la limite de détection d'un ELISA en laboratoire(Post)

    Calculer et valider la limite de détection d’un ELISA en laboratoire La limite de détection (LOD) d’un ELISA se calcule classiquement comme la moyenne des blancs plus 3 fois leur écart-type, et cette

    Dendritic Cells - Markers, Activation & Subtypes(Post)

    Immunology · Antigen PresentationDendritic Cells: Markers, Activation and SubtypesDendritic cells are the professional antigen-presenting cells that decide whether an immune response happens at all. T

    HMGB1 in inflammation and cancer(Post)

    HMGB1 Functional Overview High mobility group box 1 ( HMGB1), a member of the high-mobility group (HMG) family, was first identified in the thymus in 1973 an

    ST2 and IL33(Post)

    ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromoso

    C-Reactive Protein (CRP): Function, Levels & What They Mean(Post)

    Biomarkers · InflammationC-Reactive Protein (CRP): Structure, Function and Clinical UseCRP is the most widely measured marker of inflammation in medicine — fast to rise, fast to fall, and entirely non

    Apoptosis Unveiled: Your Complete Guide to Intrinsic & Extrinsic Pathways(Post)

    Cell Biology · Programmed Cell DeathApoptosis: Your Complete Guide to Intrinsic & Extrinsic PathwaysApoptosis is programmed cell death — the controlled, non-inflammatory removal of damaged or unwanted

    TLX as a Novel Therapeutic Target(Post)

    Danka Kozareva PhD Candidate, University College Cork The generation of neurons from stem cells The process of generating