3767 results for 'veri plex heterodim'

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By Ciara Coleman PhD General Introduction Coeliac Disease (CD) is defined as a common, chronic inflammatory disease

Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (slo

Flow cytometry is a powerful analytical technology employed in cell biology, immunology, and oncology research. It enables the rapid measurement of physical and chemical characteristics of cells o

The Notch signaling pathway is a highly conserved cellular communication system that plays a crucial role in various biological processes, including embryonic development, tissue homeostasis, a

The immune system plays a critical role in defending the body against pathogens and maintaining tissue homeostasis. Within the intricate network of immune cells, CD11b, also known as integ

For decades, the brain has been considered an immune sanctuary, protected by the formidable blood-brain barrier. This intricate defense system, while vital for safeguarding our most complex organ, ha

Coronavirus Assays | SARS-CoV-2 ELISA, Multiplex, Rapid & PCR | Assay Genie

by Ryan Wallis, PhD student, QMUL, Blizard Institute The microscopic world of cell biology was first explored by Robert Hooke in the 17th century and published in his work, Microgra

Hypoxia-inducible factors (HIFs) are pivotal in the cellular response to oxygen deprivation. These transcription factors regulate various aspects of cellular and systemic homeostasis in response t

Techniques · Gene DeliveryTransduction vs Transfection: Understanding Gene Delivery TechniquesTransduction and transfection are the two main routes for introducing genetic material into cells. Transdu

For decades, cancer drug development has focused on blocking proteins—inhibiting enzymes, antagonizing receptors, disrupting signaling pathways. Yet this approach leaves a vast landscape of disease-d

Breakthrough Discovery: Epstein-Barr Virus Identified as Primary Trigger for Lupus A groundbreaking study published in November 2025 has provided the most definitive evidence to date that the common E

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3D Organoid Cell Viability Assay (AKES081) effectively measures BENO model viability across different storage conditions. AKES081 detects significant viability differences, particularly

What are Toll Like Receptors? Toll-like receptors (TLRs) are a class of proteins that play a crucial role in the immune system's defense against microbial invaders.

The human body is a complex and intricate system where various components work together to maintain health and combat potential threats. Among these essential players are the TNF cyt

Nod-like receptors Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a br

Quick Facts About FezakinumabWhat is Fezakinumab?Fezakinumab is a human IgG1-lambda monoclonal antibody that targets interleukin-22 (IL-22), a cytokine involved in inflammatory responses

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Introduction Microtubules are key components of the cytoskeleton and are composed of alpha and beta tubulin. These dimerise in a head to tail fashion to form 13 linear protofilaments.

Bone Morphogenetic Proteins (BMP) were first discovered in the 1960s by Dr.Marshall Urist, an orthopaedic surgeon at UCLA (Urist 1965). BMPs are classically associated with their roles in limb

At Assay Genie we have created a comprehensive guide outlining everything you need to know about apoptosis! Key Takeaways: Apoptosis is a programmed cell death process, vital for tissue

Background I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dunn

Science communication (Scicomm) is currently on the up. As rebellion against the increasing distrust of science stemmed from bigoted and ignorant leaders, scientists are turning to s

Cell Death · BiomarkersCleaved Caspase-3: Activation, Function and Detection in ApoptosisCaspase-3 sits at the point where apoptotic signalling becomes irreversible. It is made as an inactive proenzym

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ST2, a member of the IL-1R Subfamily ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromoso

Cell Biology · Programmed Cell DeathApoptosis: Your Complete Guide to Intrinsic & Extrinsic PathwaysApoptosis is programmed cell death — the controlled, non-inflammatory removal of damaged or unwanted

Imagine a future where cancer cells, once masters of disguise, are forced to reveal themselves and even train the body's immune system to fight back. This isn't science fiction; it's the groundbreaki

Shelly Pathak PhD candidate, University of Leeds SAIDs Systemic Auto-inflammatory diseases (SAIDs) have been defined as a group of mainly inherited disorder

Chemokines are highly conserved cytokines that control the movement of cells around the body. All 45 members of the chemokine family can be divided into 4 subfamilies depending on th

Ovarian cancer is the fourth most common cancer in women. Ovarian cancer is when the normal cells in the ovary change and grow to form a tumour. Because the ovaries are located deep

What is Xeroderma Pigmentosum? Xeroderma pigmentosum (XP) also known De Sanctis-Cacchione syndrome is a rare genetic disorder that affects the skin, eyes and central nervous system. It is ca

Writer’s block can be a big stumbling block when trying to write your PhD thesis, grant or a paper you are trying to get publish. During the early stages of writing my PhD thesis I suffered

by Ryan Wallis, PhD Aging and Disease Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely. This is the deva

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As a PhD student delving deep into the realm of cellular biology, there is one antagonist that consistently challenges my research: mycoplasma. This microscopic bacterium, with its a

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Microglia Astrocytes Oligodendrocytes Glial

Imagine an elite squad of soldiers sent to neutralize a hidden fortress, only to find themselves wandering aimlessly in a thick, disorienting fog just outside the gates. This is the current reality f

Gene Delivery · Viral VectorsLentiviral Vectors: Design, Production and Use in Gene DeliveryLentiviral vectors integrate their cargo into the host genome and transduce dividing and non-dividing cells

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Imagine a future where the devastating impact of a stroke could be significantly mitigated, not just by managing symptoms, but by directly repairing the cellular machinery damaged during the event. T

Written by Seán Mac Fhearraigh, PhD  •  Updated: 19 May 2026  •  ~10 min read Quick Answer A sandwich ELISA uses two antibodies — a capture ant

Molecular Biology · Techniques Guide Types of PCR – 7 Methods, Principles & Applications PCR stands as a cornerstone in molecular biology, ena

Immunology · Antigen PresentationDendritic Cells: Markers, Activation and SubtypesDendritic cells are the professional antigen-presenting cells that decide whether an immune response happens at all. T

Stress and anxiety are a normal part of our daily lives and impact everything we do from our relationships with loved ones to our performance in the laboratory. Like any scientist, I experienced s

Cancer immunotherapy has revolutionized oncology, offering powerful new ways to treat various malignancies by harnessing the body's own immune system. Central to this success are immune checkpoint inh

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Molecular Biology · ProtocolsTypical Workflow of CRISPR-Cas9 Genome EditingA CRISPR experiment is only as good as the steps around the cut. This guide walks the full workflow — designing and scoring a

The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative disea

The 3D Organoid Cell Viability Assay (AKES081) demonstrated high sensitivity and low cytotoxicity, making it ideal for long incubation studies (24-48 hours) and high-throughput applicati

Both Assay Genie MORV0010 and Promega E1910 effectively quenched Firefly luciferase before Renilla detection, minimizing signal overlap. E1910 achieved 99.95% quenching efficiency, while

Treponema pallidum, the causative agent of syphilis, triggers an immune response that produces antibodies detectable by laboratory tests. Diagnosing syphilis often involves detecting thes

PCR Detection of COVID-19 (SARS-CoV-2) Contents Background Assay Information Sample Types       Upp

The Brain's Sentinels: How Microglia Shape Neuroinflammation in Disease In the intricate landscape of the human brain, a silent, ever-watchful guardian stands ready to defend against injury and invas

Key Points Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a method of gene editing that uses t

I have been in the situation that I’m sure many of us have. I work on genes, which if you name to any right-minded individual, sound like a random string of nonsensical gibberish. So, maybe