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Low Endotoxin Purified Anti-Human/Mouse IL-5 Antibody [TRFK5] (AGEL2062)

SKU:
AGEL2062
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Applications:
FC
€229 - €1,219
Frequently bought together:

Description

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Product Title:Low Endotoxin Purified Anti-Human/Mouse IL-5 Antibody [TRFK5]
SKU:AGEL2062
Size:50µg, 500µg, 1mg
Clone No:TRFK5
Synonyms:Interleukin-5;IL-5;B-cell differentiation factor I;T-cell replacing factor;TRF;
Host Species:Rat
Reactivity:Human;Mouse
Application:ICFCM;Depletion;Neut
Isotype:Rat IgG1, κ
Isotype Control:AF/LE Purified Rat IgG1, κ Isotype Control[HRPN]
Form:Liquid
Conjugation:None (AF/LE)
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P05113 P04401
Gene ID:3567,16191
Storage Buffer:0.2 μm filtered in PBS, pH 7.2. Azide Free (AF)/Low Endotoxin (LE): Contains no stabilizers or stabilizers. Endotoxin level is < 2 EU/mg as Determined by LAL gel clotting assay.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:IL-5 is a homodimeric, disulphide-linked protein produced by T-cells. Monomeric human IL-5 is a 126 amino acid protein with a reported molecular weight of 26 kD for the homodimeric protein. Mouse and human IL-5 are approximately 70% identical. IL-5 has been shown to promote the growth of immature hematopoietic BFU-E progenitors, stimulate the activation and differentiation of eosinophils, and promote the generation of cytotoxic lymphocytes. Mouse IL-5 induces the differentiation and proliferation of pre-activated B-cells and stimulates the production and secretion of IgM and IgA by B-cells stimulated with bacterial endotoxin. The TRFK5 antibody can neutralize the bioactivity of natural or recombinant IL-5.

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