Anti-BDKRB2 Antibody (CAB4756)
- SKU:
- CAB4756
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- B2R
- BK-2
- BK2
- BKR2
- BRB2
- Research Area:
- Cell Biology
Description
| Product Name: | BDKRB2 Rabbit mAb |
| Product Code: | CAB4756 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | B2R, BK-2, BK2, BKR2, BRB2 |
| Applications: | WB |
| Reactivity: | Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human BDKRB2 |
| Applications: | WB |
| Recommended Dilutions: | WB 1:500 - 1:2000 |
| Reactivity: | Rat |
| Positive Samples: | Rat kidney |
| Immunogen: | A synthesized peptide derived from human BDKRB2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 624 |
| Uniprot: | P30411 |
| Cellular Location: | Cell membrane, Multi-pass membrane protein |
| Calculated MW: | 78kDa |
| Observed MW: | 48KDa |
| UniProt Protein Function: | BKR2: a receptor for bradykinin. Bradykinin elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. |
| UniProt Protein Details: | Protein type:Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 1; Membrane protein, integral Chromosomal Location of Human Ortholog: 14q32.1-q32.2 Cellular Component: integral to plasma membrane; plasma membrane; endosome Molecular Function:bradykinin receptor activity; protein binding; protease binding; protein heterodimerization activity; type 1 angiotensin receptor binding; phosphoinositide phospholipase C activity Biological Process: vasoconstriction; metabolic process; blood circulation; negative regulation of peptidyl-serine phosphorylation; arachidonic acid secretion; vasodilation; response to salt stress; G-protein coupled receptor protein signaling pathway; elevation of cytosolic calcium ion concentration; cell surface receptor linked signal transduction; smooth muscle contraction; regulation of vasoconstriction; regulation of vascular permeability; inflammatory response; transmembrane receptor protein tyrosine kinase signaling pathway |
| NCBI Summary: | This gene encodes a receptor for bradykinin. The 9 aa bradykinin peptide elicits many responses including vasodilation, edema, smooth muscle spasm and pain fiber stimulation. This receptor associates with G proteins that stimulate a phosphatidylinositol-calcium second messenger system. Alternate start codons result in two isoforms of the protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P30411 |
| NCBI GenInfo Identifier: | 2506481 |
| NCBI Gene ID: | 624 |
| NCBI Accession: | P30411.2 |
| UniProt Related Accession: | P30411 |
| Molecular Weight: | |
| NCBI Full Name: | B2 bradykinin receptor |
| NCBI Synonym Full Names: | bradykinin receptor B2 |
| NCBI Official Symbol: | BDKRB2Â Â |
| NCBI Official Synonym Symbols: | B2R; BK2; BK-2; BKR2; BRB2Â Â |
| NCBI Protein Information: | B2 bradykinin receptor |
| UniProt Protein Name: | B2 bradykinin receptor |
| UniProt Gene Name: | BDKRB2Â Â |
| UniProt Entry Name: | BKRB2_HUMAN |
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