Bispecific In Vivo Antibodies
Bispecific Antibodies
Anti-Mouse & Anti-Human In Vivo Antibodies
Assay Genie provides high-quality, low-endotoxin (<1 EU/mg) anti-mouse and anti-human bispecific antibodies designed for immune checkpoint modulation, signalling pathway targeting, and immune effector cell engagement. Example target combinations include PD-1/PD-L1, PD-1/TIGIT PD-1/VEGF-A, CD370/PD-L1 & more.

Bispecific antibody immune-checkpoint targets include PD-1/PD-L1, PD-1/CTLA-4, PD-1/TIGIT, and additional emerging combinations.
Bispecific antibodies for immune effector cell engagement include targets such as CD370/PD-L1, CD370/CD47, and CD3/CD3
Signalling-pathway bispecific antibodies targets include PD-1/VEGF-A, PD-L1/VEGF-A, PD-1/VEGFR-2, and PD-L1/VEGFR-2.
Design antibodies tailored to your targets and applications, with custom formats for both research and development.
Industry Leading Quality
High Purity & Low Endotoxin Antibodies
Low Endotoxin levels (≤ 1.0 EU/mg) and no detectable leachable protein A or aggregates.
The mutation significantly reduces Fc-mediated effector functions while keeping affinity and stability intact.
No preservatives, stabilisers or carrier protein. Sterile PBS free from K+ or Ca2+.
30+ functional-grade bispecific antibodies & isotype controls for all applications

A: Endotoxin Analysis
Endotoxin ≤ 0.5 EU/mg for all 8 lots.
C: Non-reducing SDS Page
Non-reducing SDS-PAGE analysis demonstrating consistently high purity for all lots.
B: Chromataography Analysis
Size exclusion chromatography visualized by superimposing chromatograms for nine lots.
D: Reducing SDS Page
Reducing SDS-PAGE analysis demonstrates consistently high purity for all lots.
Our Custom Bispecific Antibody service is built around your research goals. We design a tailored production strategy to generate high-quality antibodies optimized for in vivo use - whether for preclinical studies, therapeutic research, or animal models. Every step is guided by your targets, your timelines, and our expert scientific support.
Determine if the target antigen and project objectives are suitable for in vivo antibody generation
Develop a custom production strategy tailored to the target and research applications
Generate a robust antibody response or isolate antibody-producing cells using in vivo systems
Generate, purify, and deliver functional antibodies
Bispecific Antibody Targets
Designed to support your research
Product
Reactivity
Clone
Application
Anti-mouse PD-1 / PD-1 Bispecific Antibody [RMP1-14.1 / 29F.1A12.1] In Vivo - Low Endotoxin (IVMS002)
Mouse
RMP1-14.1 / 29F.1A12.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / PD-1 Bispecific Antibody [29F.1A12.1 / RMP1-14.1] In Vivo - Low Endotoxin (IVMS003)
Mouse
29F.1A12.1 / RMP1-14.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / PD-L1 Bispecific Antibody [RMP1-14.1 / 10F.9G2.1] In Vivo - Low Endotoxin (IVMS004)
Mouse
RMP1-14.1 / 10F.9G2.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / PD-1 Bispecific Antibody [10F.9G2.1 / RMP1-14.1] In Vivo - Low Endotoxin (IVMS005)
Mouse
10F.9G2.1 / RMP1-14.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / PD-1 Bispecific Antibody [10F.9G2.1 / RMP1-14.1] In Vivo - Low Endotoxin (IVMS006)
Mouse
10F.9G2.1 / RMP1-14.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / PD-1 Bispecific Antibody [10F.9G2.1 / 29F.1A12.1] In Vivo - Low Endotoxin (IVMS006)
Mouse
10F.9G2.1 / 29F.1A12.1
ELISA, WB, FC, IHC, ICC, animal model study
In Vivo Grade Recombinant Anti-mouse PD-L1 / CTLA-4 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone UC10-4F10-11 / 10F.9G2.1) (IVMS030)
Mouse
UC10-4F10-11 / 10F.9G2.1
ELISA, WB, FC, IHC, ICC, animal model study
In Vivo Grade Recombinant Anti-mouse PD-L1 / CTLA-4 Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone 10F.9G2.1 / UC10-4F10-11) (IVMS031)
Mouse
10F.9G2.1 / UC10-4F10-11
ELISA, WB, FC, IHC, ICC, animal model study
In Vivo Grade Recombinant Anti-mouse PD-1 / TIGIT Bispecific Antibody, Mouse IgG2c LALAPG Kappa (Clone 29F.1A12.1 / 1F4) (IVMS032)
Mouse
29F.1A12.1 / 1F4
ELISA, WB, FC, IHC, ICC, animal model study
Product
Reactivity
Clone
Application
Anti-mouse CD370 / PD-L1 Bispecific Antibody [10B4 / 10F.9G2.1] In Vivo - Low Endotoxin (IVMS008)
Mouse
10B4 / 10F.9G2.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse CD370 / CD47 Bispecific Antibody [10B4 / A4] In Vivo - Low Endotoxinn (IVMS009)
Mouse
10B4 / A4
ELISA, WB, FC, IHC, ICC, animal model study
Anti-Human CD3 / CD3 Bispecific Antibody [OKT3 / UCHT1] In Vivo - Low Endotoxin(IVMS027)
Human
OKT3 / UCHT1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-Human CD3 / CD3 Bispecific Antibody [OKT3 / SP34-2] In Vivo - Low Endotoxin(IVMS028)
Human
OKT3 / SP34-2
ELISA, WB, FC, IHC, ICC, animal model study
Product
Reactivity
Clone
Application
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [RMP1-14.1 / B20-4.1.1.1] In Vivo - Low Endotoxin (IVMS0010)
Mouse
RMP1-14.1 / B20-4.1.1.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [29F.1A12.1 / B20-4.1.1.1] In Vivo - Low Endotoxin (IVMS0010)
Mouse
29F.1A12.1 / B20-4.1.1.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [29F.1A12.1 / B20-4.1.1.1] In Vivo - Low Endotoxin (IVMS0011)
Mouse
29F.1A12.1 / B20-4.1.1.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / VEGF-A Bispecific Antibody [10F.9G2.1 / B20-4.1.1.1] In Vivo - Low Endotoxin (IVMS0012)
Mouse
29F.1A12.1 / B20-4.1.1.1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [RMP1-14.1 / G6-23] In Vivo - Low Endotoxin (IVMS0013)
Mouse
RMP1-14.1 / G6-23
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [29F.1A12.1 / G6-23] In Vivo - Low Endotoxin (IVMS0014)
Mouse
29F.1A12.1 / G6-23
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / VEGF-A Bispecific Antibody [10F.9G2.1 / G6-23] In Vivo - Low Endotoxin (IVMS0001)
Mouse
10F.9G2.1 / G6-23
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [RMP1-14.1 / G6-31] In Vivo - Low Endotoxin (IVMS0015)
Mouse
RMP1-14.1 / G6-31
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGF-A Bispecific Antibody [29F.1A12.1 / G6-31] In Vivo - Low Endotoxin (IVMS0016)
Mouse
29F.1A12.1 / G6-31
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / VEGF-A Bispecific Antibody [10F.9G2.1 / G6-31] In Vivo - Low Endotoxin (IVMS0017)
Mouse
10F.9G2.1 / G6-31
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody [RMP1-14.1 / DC101] In Vivo - Low Endotoxin (IVMS0018)
Mouse
RMP1-14.1 / DC101
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-1 / VEGFR-2 Bispecific Antibody [29F.1A12.1 / DC101] In Vivo - Low Endotoxin (IVMS0019)
Mouse
29F.1A12.1 / DC101
ELISA, WB, FC, IHC, ICC, animal model study
Anti-mouse PD-L1 / VEGFR-2 Bispecific Antibody [10F.9G2.1 / DC101] In Vivo - Low Endotoxin (IVMS0020)
Mouse
10F.9G2.1 / DC101
ELISA, WB, FC, IHC, ICC, animal model study
Product
Reactivity
Isotype
Application
Anti-HEL / HEL Mouse IgG1 Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0021)
Mouse
IgG1
ELISA, WB, FC, IHC, ICC, animal model study
Anti-HEL / HEL Mouse IgG2a Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0022)
Mouse
IgG2a
ELISA, WB, FC, IHC, ICC, animal model study
Anti-HEL / HEL Mouse IgG2c-LALAPG Kappa Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0023)
Mouse
IgG2c
ELISA, WB, FC, IHC, ICC, animal model study
Human IgG1 Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0024)
Human
IgG1
ELISA, WB, FC, IHC, ICC, animal model study
Human IgG4-S228P Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0025)
Human
IgG4-S228P
ELISA, WB, FC, IHC, ICC, animal model study
Human IgG4-S228P Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0025)
Human
IgG4-S228P
ELISA, WB, FC, IHC, ICC, animal model study
Anti-HEL / HEL VHH Mouse IgG2c-LALAPG Kappa Bispecific Isotype Control Antibody In Vivo - Low Endotoxin (IVMS0026)
Mouse
IgG2c-LALAPG Kappa
ELISA, WB, FC, IHC, ICC, animal model study
Contact Form
Send us a quick message with your project details, and a member of our team will follow up to assess feasibility and guide you through the next steps!
Popular In Vivo mAbs
Optimized to achieved the best results
Antibodies for the highest-purity needs in sensitive pre-clinical studies
Explore our In vivo grade mAbs engineered to replicate reference biologics.
Fast Delivery
7 - 10 Business Day Lead Time after Manufacture
Highly Cited
We develop high quality custom multiplex assays using the best technology
PhD Level Support
Our team are trained to a PhD level to support your multiplex assay problems
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