Peptidyl-prolyl cis-trans isomerase A (PPIase A/Rotamase A/Cyclophilin A/Cyclosporin A-binding protein/PPIA/CYPA) is a cytoplasm protein which belongs to the cyclophilin-type PPIase family and PPIase A subfamily. The Cyclophilins (CyPs) are a group of proteins present in prokaryotes, as well as humans. These compounds have peptidyl-prolyl isomerase activity, which indicates that they affect the structure of proteins in cells. Proteins are more readily folded if they contain PIPPA and / or Cyclophilin A. Proline imidic peptide bonds in oligopeptides are isomerized via cis-trans isomerization as a result of this enzyme's activity. PPIA / Cyclophilin A is secreted by vascular smooth muscle cells in response to inflammatory stimuli; and could thus contribute to atherosclerosis. It is not essential for mammalian cell viability. Cytosolic cyclophilin A may bind to several HIV proteins, including p55 gag; Vpr; and capsid protein, and is required for the formation of infectious HIV virions. ANXA5/Annexin A5 Recombinant Protein is a highly pure recombinant protein developed by Assay Genie for use in a range of applications.
Product Name:
ANXA5/Annexin A5 Recombinant Protein (RPES3078)
Product Code:
RPES3078
Size:
20 µg
Species:
Human
Expressed Host:
E.coli
Synonyms:
ANXA5,Annexin V,Unconjugated Annexin V,Annexin-5,Anchorin CII,Calphobindin I,Endonexin II,Lipocortin V,Placental anticoagulant protein 4,Placental anticoagulant protein I,Thromboplastin inhibitor,Vascular anticoagulant-alpha
Accession:
P08758
Sequence:
Met 1-Asp 320
Fusion tag:
Endotoxin:
Please contact us for more information.
Protein Construction:
A DNA sequence encoding the human ANXA5 (P08758) (Met 1-Asp 320) was expressed and purified.
Purity:
> 90 % as determined by reducing SDS-PAGE.
Mol Mass:
35.9 kDa
AP Mol Mass:
34 kDa
Formulation:
Lyophilized from sterile 50mM Tris; 240mM NaCl; pH 8.5
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
