Carboxypeptidase B1 is an exopeptidase which specifically cleaves the C-terminal Arg and Lys residues with a preference for Arg. Expressed mainly in pancreas, CPB1 is a useful serum marker for acute pancreatitis and pancreatic graft rejection.Human CPB1 consists of a signal peptide, a pro region, and a mature chain. The purified rhCPB1 corresponds to the pro form, which can be activated by trypsin, the only pancreatic protease capable of generating active enzyme from the zymogen in vitro.
Product Name:
Carboxypeptidase B1/CPB1 Recombinant Protein (RPES4443)
Recombinant Human Carboxypeptidase B is produced by our Mammalian expression system and the target gene encoding His16-Tyr417 is expressed with a 6His tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
46.9 kDa
AP Mol Mass:
47 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of 20mM MES, 150mM NaCl, pH 5.5.
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
