Interleukin-20 receptor subunit beta?IL20RB? is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytokine receptors : cytokine receptors that bind type I and type II interferons; cytokine receptors that bind members of the interleukin-10 family (interleukin-10, interleukin-20 and interleukin-22). Type II cytokine receptors are similar to type I cytokine receptors except they do not possess the signature sequence WSXWS that is characteristic of type I receptors. They are expressed on the surface of certain cells, which bind and respond to a select group of cytokines. These receptors are related predominantly by sequence similarities in their extracellular portions that are composed of tandem Ig-like domains. The intracellular domain of type II cytokine receptors is typically associated with a tyrosine kinase belonging to the Janus kinase (JAK) family
Product Name:
Human IL-20RB Recombinant Protein (RPES1223)
Product Code:
RPES1223
Size:
10µg
Species:
Human
Expressed Host:
Human Cells
Synonyms:
Interleukin-20 receptor subunit beta,IL-20 receptor subunit beta,IL-20R-beta,IL-20RB,IL-20R2,DIRS1,hCG_2022374, FNDC6, MGC34923, fibronectin type III domain containing 6, interleukin-20 receptor II
Accession:
Q6UXL0
Sequence:
Asp30-Ala230
Fusion tag:
C-Fc
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Human Interleukin-20 receptor subunit beta/IL-20RB is produced by our Mammalian expression system and the target gene encoding Asp30-Ala230 is expressed with a Fc tag at the C-terminus.
Purity:
> 95 % as determined by reducing SDS-PAGE.
Mol Mass:
49.6 kDa
AP Mol Mass:
70 kDa
Formulation:
Supplied as a 0.2 µm filtered solution of PBS, pH 7.4 .
Shipping:
This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs.Upon receipt, store it immediately at<-20°C.
Stability and Storage:
Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
