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AQP4 Antibody (PACO00414)

SKU:
PACO00414
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
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Description

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Antibody Name:AQP4 Antibody
Antibody SKU:PACO00414
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from the Internal region of human AQP4.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:AQP4; Aquaporin-4; AQP-4; Mercurial-insensitive water channel; MIWC; WCH4
UniProt Protein Function:AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described
UniProt Protein Details:

Protein type:Transporter, aquaporin family; Membrane protein, integral; Channel, misc.; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 18q11.2-q12.1

Cellular Component: basolateral plasma membrane; cytoplasm; external side of plasma membrane; integral to membrane; plasma membrane

Molecular Function:glycerol channel activity; water channel activity; water transporter activity

Biological Process: glycerol transport; multicellular organismal water homeostasis; renal water homeostasis; transmembrane transport; transport; water transport

NCBI Summary:This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]
UniProt Code:P55087
NCBI GenInfo Identifier:2506859
NCBI Gene ID:361
NCBI Accession:P55087.2
UniProt Secondary Accession:P55087,P78564,
UniProt Related Accession:P55087
Molecular Weight:32,300 Da
NCBI Full Name:Aquaporin-4
NCBI Synonym Full Names:aquaporin 4
NCBI Official Symbol:AQP4  
NCBI Official Synonym Symbols:MIWC; WCH4  
NCBI Protein Information:aquaporin-4
UniProt Protein Name:Aquaporin-4
UniProt Synonym Protein Names:Mercurial-insensitive water channel; MIWC; WCH4
Protein Family:Aquaporin
UniProt Gene Name:AQP4  
UniProt Entry Name:AQP4_HUMAN

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