The EDG1/HEXIM1 Monoclonal Antibody (CAB3997) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards the EDG1 protein in human samples, making it ideal for use in Western blot applications.The EDG1 protein, also known as sphingosine-1-phosphate receptor 1 (S1PR1), is involved in signaling pathways that control diverse physiological processes such as immune response modulation, vascular development, and cell trafficking.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse, Rat samples.
Product Name:
EDG1/HEXIM1 Monoclonal Antibody
SKU:
CAB3997
Size:
20μL, 100μL
Reactivity:
Human, Mouse, Rat
Clone Number:
ARC0881
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Purification Method
Affinity purification
Gene ID
1901
RRID
AB_2863172
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using EDG1/HEXIM1 Rabbit mAb (CAB3997) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
