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FITC Anti-Rat CD161 Antibody [3.2.3] (AGEL3427)

Datasheet MSDS
SKU AGEL3427
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Rat
Host Species Mouse
Isotype Mouse IgG1, k
Clone 3.2.3
Conjugation FITC
€100 - €250

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Description

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FITC Anti-Rat CD161 Antibody [3.2.3]

The FITC Anti-Rat CD161 Antibody (3.2.3) is a powerful tool for researchers studying immune cells in rat models. CD161, also known as NKR-P1A, is a C-type lectin-like receptor expressed on natural killer cells and subsets of T cells. This antibody, conjugated with FITC for fluorescent detection, specifically targets CD161, enabling precise visualization and analysis of CD161-expressing cells in flow cytometry and immunofluorescence applications.With its high specificity and sensitivity, the FITC Anti-Rat CD161 Antibody (3.2.3) offers researchers a reliable method to investigate the function and distribution of CD161 in rat immune systems.

Understanding the role of CD161 in immune responses is crucial for unraveling the complexities of immune regulation and developing targeted therapies for conditions such as infectious diseases, inflammation, and autoimmune disorders.By incorporating the FITC Anti-Rat CD161 Antibody (3.2.3) into their experimental designs, researchers can gain valuable insights into the mechanisms underlying immune cell interactions and responses in rat models, paving the way for advancements in immunology research and therapeutic development.

Product Title:FITC Anti-Rat CD161 Antibody [3.2.3]
SKU:AGEL3427
Size:50 Tests, 100 Tests, 200 Tests
Clone No:3.2.3
Synonyms:NKR-P1; CD161a/CD161b; NKR-P1a/KLRB1a;
Host Species:Mouse
Reactivity:Rat
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:FITC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P27471 A4KWA1 Q5NKN4 Q5NKN2
Gene ID:362443
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD161 is a 30 kD type II transmembrane C-type lectin, expressed as a homodimer. Rat NKR-P1 receptors are primarily expressed on NK cells, a subset of T cells, dendritic cells, and activated monocytes. There are three different types of NKR-P in rat, namely NKR-P1a, NKR-P1b, and NKR-P1c. NKR-P1a does not contain an ITIM structure and is an activating receptor, while NKR-P1b contains an ITIM and displays inhibitory function. LLT-1 (ligand lectin like transcript 1) is the ligand, while KLR (killer cell lectin like) functions as a receptor.
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