Human MRP1 (Multidrug Resistance Associated Protein 1) CLIA Kit
The Human MRP1 (Multidrug Resistance-Associated Protein 1) CLIA Kit is specifically designed for the accurate measurement of MRP1 levels in human samples such as serum, plasma, and cell culture supernatants. With its high sensitivity and specificity, this kit provides reliable and reproducible results, making it suitable for a variety of research purposes.MRP1 is a vital protein involved in multidrug resistance, playing a key role in drug efflux and resistance to chemotherapy agents. Its overexpression has been linked to various diseases, including cancer, making it an important biomarker for studying drug resistance mechanisms and developing targeted therapies.Overall, the Human MRP1 CLIA Kit is an essential tool for researchers investigating drug resistance and exploring potential strategies to overcome this challenge in the treatment of various diseases.
Product Name:
Human MRP1 (Multidrug Resistance Associated Protein 1) CLIA Kit
SKU:
HUES01088
Size:
96 Assays
Detection Method:
Chemiluminescence
Assay type:
Sandwich-CLIA
Assay time:
3 h 30 min
Sensitivity:
37.5 pg/mL
Detection range:
62.5-4000 pg/mL
Reovery:
80%-120%
This kit uses a sandwich chemiluminescence immunoassay (CLIA) principle. The microplate is pre-coated with an antibody specific to the target protein. Standards or samples are added to the wells and bind to the immobilized antibody. A biotinylated detection antibody is then added, followed by HRP-conjugated streptavidin to form a sandwich complex. After washing to remove unbound components, a chemiluminescent substrate is added. The HRP enzyme catalyzes a light-emitting reaction. The intensity of the emitted light is directly proportional to the concentration of the target protein in the sample. The signal is measured using a luminometer, and the concentration of the analyte is calculated based on a standard curve.
