Human TGFB2 Recombinant Protein (hFc Tag) (HDPT0408)

SKU:
HDPT0408
€550

Description

Human TGFB2 Recombinant Protein (hFc Tag)

Description:This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. Disruption of the TGF-beta/SMAD pathway has been implicated in a variety of human cancers. A chromosomal translocation that includes this gene is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. Mutations in this gene may be associated with Loeys-Dietz syndrome. This gene encodes multiple isoforms that may undergo similar proteolytic processing. [provided by RefSeq, Aug 2016]
Product name:Human TGFB2 Recombinant Protein (hFc Tag)
Synonyms:G-TSF; LDS4; TGF-beta2
Type:protein
Size:50 µg
Name:TGFB2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:TGFB2 (Ala303-Ser414)+hFc (Glu99-Ala330)
Gene ID:
Uniprot:P61812
Molecular Weight:37.84 kDa
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Additional Information

Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
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