Human TLR2 Recombinant Protein (hFc Tag) (HDPT0412)

SKU:
HDPT0412
€550

Description

Human TLR2 Recombinant Protein (hFc Tag)

Description:The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the host's inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Product name:Human TLR2 Recombinant Protein (hFc Tag)
Synonyms:CD282; TIL4
Type:protein
Size:50 µg
Name:TLR2
Origin:Human
Source:HEK293
Protein Type:Recombinant
Application:Contact Technical Support
Purity:Contact Technical Support
Purification:affinity purification
Format:Lyophilized
Conjugate:C-Human Fc
Storage:Store at -80°C for 12 months (Avoid repeated freezing and thawing)
Usage:Research use only
Buffer:Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
Reconstitution:Reconstitute with deionized water
Sequence:TLR2 (Glu21-Thr588)+hFc (Glu99-Ala330)
Gene ID:
Uniprot:O60603
Molecular Weight:88 kDa
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Additional Information

Product Type:
Recombinant Protein
Host Species:
HEK293
Reactivity:
Human
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