The KRT35 Polyclonal Antibody (PACO40054) is a valuable tool for researchers studying keratin 35 (KRT35), a type I keratin protein primarily found in the hair follicle. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blot and immunohistochemistry.KRT35 is a key component of the hair structure and is involved in maintaining the integrity and strength of hair fibers. Research into KRT35 can provide insights into hair growth disorders, such as alopecia, as well as potential therapeutic targets for hair-related conditions.
The KRT35 Polyclonal Antibody enables precise detection and analysis of KRT35 protein expression in different cell types and tissues, making it an essential tool for studies in dermatology, hair biology, and regenerative medicine. By understanding the role of KRT35, researchers can advance our knowledge of hair biology and develop innovative strategies for hair loss prevention and treatment.
Western blot. All lanes: KRT35 antibody at 4µg/ml + PC-3 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 51 kDa. Observed band size: 51 kDa.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO40054 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human skin tissue using PACO40054 at dilution of 1:100.
Keratin, type I cuticular Ha5 (Hair keratin, type I Ha5) (Keratin-35) (K35), KRT35, HHA5 HKA5 KRTHA5
UniProt Protein Function:
KRTHA5: is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]Protein type: Motility/polarity/chemotaxis; CytoskeletalChromosomal Location of Human Ortholog: 17q21.2Cellular Component: extracellular space; intermediate filamentMolecular Function: structural molecule activityBiological Process: anatomical structure morphogenesis
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the keratin gene family. This type I hair keratin is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
