Anti-MAOA Antibody (PACO06624)

Antibody Name:	MAOA Antibody (PACO06624)
Antibody SKU:	PACO06624
Size:	50ug
Host Species:	Rabbit
Tested Applications:	ELISA, WB, IHC
Recommended Dilutions:	ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:	Human, Mouse, Rat
Immunogen:	Synthesized peptide derived from the Internal region of human MAO-A.

Form:	Liquid
Storage Buffer:	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:	Polyclonal
Isotype:	IgG
Conjugate:	Non-conjugated

	Western Blot analysis of 22RV1 MCF7 cells using MAO-A Polyclonal Antibody.
	Western Blot analysis of HeLa cells using MAO-A Polyclonal Antibody.

Synonyms:

MAOA; Amine oxidase [flavin-containing] A; Monoamine oxidase type A; MAO-A

UniProt Protein Function:	MAOA: Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine. Defects in MAOA are the cause of Brunner syndrome (BRUNS). Brunner syndrome is a form of X-linked non- dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. Belongs to the flavin monoamine oxidase family.
UniProt Protein Details:	Protein type:EC 1.4.3.4; Membrane protein, integral; Amino Acid Metabolism - tryptophan; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Amino Acid Metabolism - histidine; Amino Acid Metabolism - arginine and proline; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - glycine, serine and threonine; Oxidoreductase; Amino Acid Metabolism - tyrosine Chromosomal Location of Human Ortholog: Xp11.3 Cellular Component: mitochondrial outer membrane; mitochondrion; integral to membrane Molecular Function:amine oxidase activity Biological Process: synaptic transmission; biogenic amine metabolic process; neurotransmitter catabolic process; dopamine catabolic process; xenobiotic metabolic process; neurotransmitter secretion; neurotransmitter biosynthetic process Disease: Brunner Syndrome
NCBI Summary:	This gene is one of two neighboring gene family members that encode mitochondrial enzymes which catalyze the oxidative deamination of amines, such as dopamine, norepinephrine, and serotonin. Mutation of this gene results in Brunner syndrome. This gene has also been associated with a variety of other psychiatric disorders, including antisocial behavior. Alternatively spliced transcript variants encoding multiple isoforms have been observed. [provided by RefSeq, Jul 2012]
UniProt Code:	P21397
NCBI GenInfo Identifier:	113978
NCBI Gene ID:	4128
NCBI Accession:	P21397.1
UniProt Secondary Accession:	P21397,Q16426, B4DF46,
UniProt Related Accession:	P21397
Molecular Weight:	527
NCBI Full Name:	Amine oxidase
NCBI Synonym Full Names:	monoamine oxidase A
NCBI Official Symbol:	MAOA
NCBI Official Synonym Symbols:	MAO-A
NCBI Protein Information:	amine oxidase [flavin-containing] A; amine oxidase [flavin-containing] A; monoamine oxidase type A
UniProt Protein Name:	Amine oxidase [flavin-containing] A
UniProt Synonym Protein Names:	Monoamine oxidase type A; MAO-A
Protein Family:	Amine oxidase
UniProt Gene Name:	MAOA
UniProt Entry Name:	AOFA_HUMAN

Antibodies	ELISA Kits
Anti-MAOA Antibody (CAB1354)	Human MAO-A / Monoamine Oxidase A ELISA Kit
Anti-MAOA Antibody (CAB14024)	Human Amine oxidase [flavin-containing] A (MAOA) ELISA Kit
Anti-Monoamine Oxidase A Antibody (CAB4105)
MAOA Antibody (PACO10356)

Secondary Antibody

Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)