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Biotin Anti-Mouse CD120b Antibody [TR75-54.7] (AGEL0162)

SKU:
AGEL0162
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Mouse
Host Species:
Hamster
Isotype:
IgG
Clone:
TR75-54.7
Conjugation:
Biotin
Applications:
FC
€149 - €219
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Title:Biotin Anti-Mouse CD120b Antibody [TR75-54.7]
SKU:AGEL0162
Size:25µg, 100µg
Clone No:TR75-54.7
Synonyms:Tumor necrosis factor receptor superfamily member 1B;Tnfrsf1b;Tumor necrosis factor receptor 2;TNF-R2;TNF-RII;TNFR-II;p75;p80 TNF-alpha receptor;CD120b;
Host Species:Armenian Hamster
Reactivity:Mouse
Application:FCM
Isotype:Armenian Hamster IgG
Isotype Control:Biotin Armenian Hamster IgG Isotype Control[PIP]
Form:Liquid
Conjugation:Biotin
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Swissprot:P25119
Gene ID:21938
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD120b is a 75 kD type I transmembrane protein, also known as Tumor Necrosis Factor Receptor Type II (TNFRII) or p75. It is expressed on a variety of cells at low levels; the expression is upregulated upon activation. This receptor binds both TNF-α and LT-α (also known as TNF-β). In association with TRAF1 and TRAF2, the receptor crosslinking induced by TNF-α or LT-α trimers is critical for signal transduction, leading to apoptosis, NF-kB activation, increased expression of proinflammatory genes, tumor necrosis, and cell differentiation depending on cell type and differentiation state.

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