The OR5B12 Monoclonal Antibody (PACO02862) is a powerful tool for researching OR5B12, a member of the olfactory receptor family implicated in the sense of smell. This antibody, developed for use in immunohistochemistry applications, is highly specific to human samples and has been validated for its reliability and sensitivity.OR5B12 is a sensory protein expressed in olfactory neurons, where it plays a key role in detecting specific odors and transmitting signals to the brain for interpretation. By targeting OR5B12 with this antibody, researchers can gain insights into the mechanisms of olfaction and sensory perception, as well as explore potential applications in areas such as fragrance development and neurobiology research.
The ability to accurately detect and analyze OR5B12 expression in various tissues and cell types makes this monoclonal antibody an indispensable tool for studies focusing on the sense of smell, sensory processing, and the molecular mechanisms underlying olfactory perception. Its specificity and reliability make it a valuable resource for investigators seeking to deepen our understanding of the complex processes involved in odor detection and interpretation.
Antibody Name:
OR5B12 Antibody
Antibody SKU:
PACO02862
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IF
Recommended Dilutions:
WB:1:500-1:2000, IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 5B12.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR5B12: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: Receptor, GPCR; Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integralChromosomal Location of Human Ortholog: 11q12.1Cellular Component: plasma membraneMolecular Function: odorant binding; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
