The OR8U1, OR8U8, OR8U9 Antibody (PACO03654) is a highly specific polyclonal antibody designed for research involving the OR8U1, OR8U8, and OR8U9 odorant receptors. These receptors play a critical role in olfactory function, specifically in detecting and responding to specific odor molecules.Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in various applications such as immunofluorescence and flow cytometry. It binds specifically to the OR8U1, OR8U8, and OR8U9 proteins, enabling researchers to detect and analyze these receptors in different cell types and tissues.The role of OR8U1, OR8U8, and OR8U9 in olfactory perception makes them valuable targets for research into sensory processing and neurological disorders.
Understanding how these receptors function can provide insights into how the brain processes and interprets odors, and how dysfunction may contribute to conditions such as anosmia or altered perception of smell.Overall, the OR8U1, OR8U8, OR8U9 Antibody (PACO03654) is a valuable tool for researchers studying olfactory function, sensory processing, and neurobiology. Its specificity and reliability make it ideal for a wide range of studies exploring the complexities of the human sense of smell.
Antibody Name:
OR8U1/OR8U8/OR8U9 Antibody
Antibody SKU:
PACO03654
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Olfactory receptor 8U1/8/9.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
OR8U1: Odorant receptor (Potential). Belongs to the G-protein coupled receptor 1 family.Protein type: GPCR, family 1; Receptor, GPCR; Membrane protein, multi-pass; Membrane protein, integralChromosomal Location of Human Ortholog: 11q12.1Cellular Component: integral to membrane; plasma membraneMolecular Function: G-protein coupled receptor activity; olfactory receptor activityBiological Process: G-protein coupled receptor protein signaling pathway; detection of chemical stimulus involved in sensory perception of smell
UniProt Protein Details:
NCBI Summary:
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
