PRPS1 Monoclonal Antibody [PAT1E11AT] (CPAB0184)
- SKU:
- CPAB0184
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2a
- Clone:
- PAT1E11AT
- Applications:
- WB
- ELISA
Frequently bought together:
Description
system_update_alt Datasheet
Product Name: | PRPS1 Antibody |
Product Sku: | CPAB0184 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human PRPS1 mAb, clone PAT1E11AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PRPS1 protein 1-318 amino acids purified from Ecoli. |
Clone: | PAT1E11AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | PRPS1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2a |
Background: | PRPS1 catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS1 catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is essential for purine metabolism and nucleotide biosynthesis. Defects in PRPS1 result in phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. |
Synonyms: | ARTS, CMTX5, PPRibP, PRSI, DFN2, Ribose-phosphate pyrophosphokinase 1, DFNX1, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1, KIAA0967. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |