LYN contains one protein kinase domain, one SH2 domain, one SH3 domain, and the protein kinase domain plays an important role in its localization in the cell membrane. LYN is also thought to participate in signal transduction from cell surface receptors that lack intrinsic tyrosine kinase activity. In addition, LYN is associated with a number of cell surface receptors including the B cell antigen receptor and immunoglobulin E receptor (FceRI).
Product Name:
Cynomolgus OX40/TNFRSF4 Recombinant Protein (RPES2571)
Product Code:
RPES2571
Size:
10µg
Species:
Cynomolgus
Expressed Host:
Human Cells
Synonyms:
Tyrosine-protein kinase Lyn (LYN), Lck/Yes-related novel protein tyrosine kinase, V-yes-1 Yamaguchi sarcoma viral related oncogene homolog, p53Lyn, p56Lyn and JTK8,
Accession:
P07948
Sequence:
Gly2-Pro512
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
Recombinant Cynomolgus OX40L Receptor is produced by our Mammalian expression system and the target gene encoding Lys28-Ala214 is expressed with a 6His tag at the C-terminus.
Purity:
> 95% as determined by reducing SDS-PAGE.
Mol Mass:
21.3 kDa
AP Mol Mass:
35-50 kDa
Formulation:
Lyophilized from a 0.2 µm filtered solution of PBS,pH7.4.
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
