Description
Recombinant Human ABHD4 Protein
The Recombinant Human ABHD4 Protein is a biologically active recombinant protein that plays a significant role in various cellular processes and signaling pathways in human biology. This protein is widely employed in immunological research, cell biology studies, protein-protein interaction analyses, and therapeutic development, providing researchers with a reliable tool for investigating ABHD4 function and its implications in health and disease.
This product (SKU: RPCB2035) is produced using Baculovirus-Insect Cells and features a N-His tag for convenient detection and purification. The protein exhibits a calculated molecular weight of 40 kDa. with an observed molecular weight of - under denaturing conditions, achieving ≥ 80% as determined by SDS-PAGE., ensuring exceptional quality and consistency for research applications.
Key Features
| High Purity by Affinity Chromatography | |
| Mammalian & Bacterial Expression Systems | |
| High lot-to-lot consistency via strict QC |
| Product Name: | Recombinant Human ABHD4 Protein |
| SKU: | RPCB2035 |
| Size: | 20 μg , 100 μg |
| Reactivity: | Human |
| Synonyms: | ABHD4, (Lyso)-N-acylphosphatidylethanolamine lipase, 3.1.1.-, Alpha/beta hydrolase domain-containing protein 4, Abhydrolase domain-containing protein 4, Alpha/beta-hydrolase 4 |
| Tag: | N-His |
| Expression Host: | Baculovirus-Insect Cells |
| Calculated MW: | 40 kDa. |
| Gene ID: | 63874 |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Human ABHD4 Protein (RPCB2035), tested reactivity in Baculovirus-Insect Cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | < 1 EU/μg of the protein by LAL method. |
| Purity: | ≥ 80% as determined by SDS-PAGE. |
| Formulation: | Lyophilized from sterile 50mM Tris, 100mM NaCl, pH 8.0. |
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt. After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
Abhydrolase domain containing 4 (ABHD4), also known as alpha/beta-hydrolase 4 (ABH4), or lyso-N-acylphosphatidylethanolamine lipase, which belongs to the ABHD4/ABHD5 subfamily of peptidase S33 family. Abhydrolase domain containing (ABHD) gene was a small group belongs to alpha/beta hydrolase superfamily. Known members of this group are all found to be involved in important biochemical processes and related to various diseases. The alpha/beta-hydrolase 4 (ABH4) is a lysophospholipase/phospholipase B that selectively hydrolyzes N-acyl phosphatidylethanolamines (NAPEs) and lysoNAPEs. ABH4 accepts lysoNAPEs bearing both saturated and polyunsaturated N-acyl chains as substrates and displays a distribution that closely mirrors lysoNAPE-lipase activity in mouse tissues. The existence of an NAPE-PLD-independent route for NAE biosynthesis and suggest that ABH4 plays a role in this metabolic pathway by acting as a (lyso)NAPE-selective lipase.
