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Human Cadherin-8/CDH8 Recombinant Protein (RPES3865)

SKU:
RPES3865
Product Type:
Recombinant Protein
Species:
Human
Research Area:
Cell Biology
€300
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Description

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Human Cadherin-8/CDH8 Recombinant Protein

Cadherin-8 (CDH8) is a type II classical cadherin from the cadherin superfamily. Member of the Cadherin superfamily are integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small highly conserved C-terminal cytoplasmic domain. Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells. The extracellular domain of CDH8 contains five cadherin domains. CDH8 is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance.